Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Quality Control of 31643-49-9.
Wang, Chongchong;Li, Yanqing;Yang, Weijie;Zhou, Lin;Wei, Shaohua research published 《 Nanozyme with Robust Catalase Activity by Multiple Mechanisms and Its Application for Hypoxic Tumor Treatment》, the research content is summarized as follows. Utilizing catalase-mimicking nanozymes to produce O2 is an effective method to overcome tumor hypoxia. However, it is challenging to fabricate nanozymes with ultrahigh catalytic activity. Palladium nanosheet (Pd NS), a photothermal agent for photothermal therapy (PTT), has superior catalase-mimicking activity. Here, titanium dioxide (TiO2) is used to modify Pd NS (denoted Pd@TiO2) by a simple one-step method to improve its catalytic activity about 8 times. The enhancement mechanism′s fundamental insights are discussed through experiments and d. functional theory calculations Next, zinc phthalocyanine is loaded on Pd@TiO2 to form a nanomotor (denoted PTZCs) with the synergistic activities of photodynamic therapy and PTT. PTZCs inherit the catalase activity of Pd@TiO2 to facilitate the decomposition of endogenous H2O2 to O2, which can relieve tumor hypoxia and propel PTZC migration to expand the reach of PTZCs, further enhancing its synergistic treatment outcome both in vitro and in vivo. It is proposed that this work can provide a simple and effective strategy for catalytic activity enhancement and bring a critical new perspective to studying and guiding the nanozyme design.
Quality Control of 31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts