Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Safety of 4-Nitrophthalonitrile.
Wierzchowski, Marcin;Ziental, Daniel;Lazewski, Dawid;Korzanski, Artur;Gielara-Korzanska, Agnieszka;Tykarska, Ewa;Dlugaszewska, Jolanta;Sobotta, Lukasz research published 《 New Metallophthalocyanines Bearing 2-Methylimidazole Moieties-Potential Photosensitizers against Staphylococcus aureus》, the research content is summarized as follows. Newly developed tetra- and octasubstituted methimazole-phthalocyanine conjugates as potential photosensitizers have been obtained. Synthesized intermediates and final products were characterized by the MALD-TOF technique and various NMR techniques, including 2D methods. Single-crystal X-ray diffraction was used to determine the crystal structures of dinitriles. The studied phthalocyanines revealed two typical absorption bands-the Soret band and the Q band. The most intense fluorescence was observed for octasubstituted magnesium(II) phthalocyanine in DMF (ΦFL = 0.022). The best singlet oxygen generators were octasubstituted magnesium(II) and zinc(II) phthalocyanines (ΦΔ 0.56 and 0.81, resp.). The studied compounds presented quantum yields of photodegradation at the level between 10-5 and 10-6. Due to their low solubility in a water environment, the liposomal formulations were prepared Within the studied group, octasubstituted zinc(II) phthalocyanine at the concentration of 100 μM activated with red light showed the highest antibacterial activity against S. aureus equal to a 5.68 log reduction of bacterial growth.
Safety of 4-Nitrophthalonitrile, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts