Freeman, Fillmore; Kim, Darrick S. H. L. published an article in 1989, the title of the article was Preparation of 2-alkyl- and 2-aryl-5-amino-4-cyano-1,3-oxazoles.Application In Synthesis of 2-Aminomalononitrile 4-methylbenzenesulfonate And the article contains the following content:
Aminopropanedinitrile p-toluenesulfonate reacts with acid chlorides to give 5-amino-4-cyano-1,3-oxazoles I (R = Me, Et, CHMe2, Ph, 4-MeOC6H4, 4-O2NC6H4, 2-furyl) in 51-95% yields. The experimental process involved the reaction of 2-Aminomalononitrile 4-methylbenzenesulfonate(cas: 5098-14-6).Application In Synthesis of 2-Aminomalononitrile 4-methylbenzenesulfonate
The Article related to acid chloride cyclocondensation aminomalonitrile tosylate, oxazole amino cyano aryl alkyl, Heterocyclic Compounds (More Than One Hetero Atom): Oxazoles, Isoxazoles and other aspects.Application In Synthesis of 2-Aminomalononitrile 4-methylbenzenesulfonate
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts