On November 6, 2003, Moeller, Hinrich; Oberkobusch, Doris; Hoeffkes, Horst published a patent.HPLC of Formula: 2510-01-2 The title of the patent was Hair dyes containing isatin derivatives. And the patent contained the following:
The invention concerns hair dyes that contain isatin derivatives and that can be used with or without oxidation agents to color hair; the derivatives are bis-isatin compounds and mols. including isatin coupled to 1H-pyrrol-2,3-dione via an aromatic group. The hair dye compositions can further include dyes that are primary or secondary amines, hydroxydes of aromatic and N-heterocyclic compounds, amino acids and carboxylic acids. Direct dyes can be added; hydrogen peroxide is the used oxidation agent; anionic, zwitterionic and nonionic surfactants are included. Thus 5 mmol (1H,6H)-2,3,7,8-Tetrahydropyrrolo[2’3′: 1,2]-naphtho[5,6-b]pyrrolo-2,3,7,8-tetrone and 5 mmol 3-amino-2-methylamino-6-methyoxypyridine were each suspended in 25 mL water at 50°C. After cooling to 30°C the suspensions were mixed; 5 mmol sodium acetate, one drop of 25 % fatty ether sulfate solution were added and pH 9 was adjusted with diluted sodium hydroxide. The dye mixture was applied to hair; a dark brown color was obtained. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).HPLC of Formula: 2510-01-2
The Article related to hair dye isatin derivative aromatic n heterocyclic amine hydroxide, Essential Oils and Cosmetics: Hair Preparations and other aspects.HPLC of Formula: 2510-01-2
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts