On February 24, 2021, Cheng, Qiuli; Asha, Anika Benozir; Liu, Yang; Peng, Yi-Yang; Diaz-Dussan, Diana; Shi, Zuosen; Cui, Zhanchen; Narain, Ravin published an article.Product Details of 5098-14-6 The title of the article was Antifouling and Antibacterial Polymer-Coated Surfaces Based on the Combined Effect of Zwitterions and the Natural Borneol. And the article contained the following:
The development and application of natural antibacterial materials have always been the focus of biomedical research. Borneol as a natural antibacterial compound has received extensive attention. However, the hydrophobicity caused by its unique structure limits its application range to a certain extent. In this study, we combine zwitterionic 2-methacryloyloxyethyl phosphorylcholine (MPC) with a complex bicyclic monoterpene structure borneol compound and prepare an excellent antifouling and antibacterial surface via the Schiff-base bond. The prepared coating has excellent hydrophilicity verified by the contact angle (CA), and its polymer layer is confirmed by XPS. The zwitterion MPC and borneol moieties in the copolymer play a coordinating role, relying on super hydration and the special stereochem. structure to prevent protein adsorption and inhibit bacterial adhesion, resp., which are demonstrated by bovine serum albumin (BSA) adsorption and antibacterial activity test. Moreover, the water-soluble borneol derivative as the antibacterial surfaces we designed here was biocompatible toward MRC-5 (lung fibroblasts), as showed by in vitro cytotoxicity assays. Such results indicate the potential application of the as-prepared hydrophilic surfaces in the biomedical materials. The experimental process involved the reaction of 2-Aminomalononitrile 4-methylbenzenesulfonate(cas: 5098-14-6).Product Details of 5098-14-6
The Article related to antifouling antibacterial polymer surface coating zwitterion borneol biocompatibility, antibacterial, antifouling, biocompatibility, hydrophilic, zwitterion, Pharmaceuticals: Prosthetics and Medical Goods and other aspects.Product Details of 5098-14-6
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts