Gao, Liuzhou published the artcile1,2-Silylpyridylation Reaction of Aryl Alkenes with Silylboronate, Application of Picolinonitrile, the main research area is silylboronate silylpyridylation reaction of aryl alkene cyanopyridine DFT; silylalkylated pyridine preparation.
A metal-free silyl-pyridylation of alkenes using silyl boronates and B2pin2 through a pyridine-mediated B-interelement activation was demonstrated, which provides a practical strategy for a variety of C4-silylalkylated pyridines. DFT calculations and control experiments show that the reaction proceeds through a silyl radical addition/radical-radical coupling sequence. This protocol features a broad substrate scope and excellent functional group compatibility, and thus it showcases great potential in the late-stage modification of bioactive mols.
Organic Letters published new progress about Amination (1,2-silylpyridylation reaction). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Application of Picolinonitrile.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts