Xiong, Biquan published the artcileSilver-catalyzed regioselective 1,6-hydroarylation of para-quinone methides with anilines and phenols, Related Products of nitriles-buliding-blocks, the main research area is alpha diarylmethyl aniline phenol preparation regioselective; para quinone methide aniline phenol hydroarylation silver catalyst.
A simple and efficient method for the silver-catalyzed regioselective 1,6-hydroarylation of para-quinone methides (p-QMs) with anilines and phenols has been established. Without the need for pre-protection, a broad range of anilines (primary amine, secondary amine and tertiary amine), phenols and para-quinone methides are well tolerated under mild conditions, giving the corresponding 1,6-hydroarylation products with moderate to good yields. Moreover, a series of modified natural products can be synthesized via this simple method. Control experiments were also performed to gain insights into the plausible reaction mechanism. This protocol has high atom economy, and may have significant implications for the formation of C(sp3)-C(sp2) bonds in organic synthesis.
Organic Chemistry Frontiers published new progress about Hydroarylation. 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Related Products of nitriles-buliding-blocks.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts