Moore, Jared T. published the artcileCatalytic alkene cyclization reactions for the stereoselective synthesis of complex “”terpenoid-like”” heterocycles, Formula: C9H9NO2, the main research area is terpenoid like heterocyclic compound preparation stereoselective synthesis.
A new catalytic synthesis of densely substituted tetrahydroquinoline derivatives is described. This reaction forms up to two rings, three bonds and three stereogenic centers with excellent stereocontrol and regiocontrol in a single step. Although control experiments demonstrate that the active catalyst is protic acid, Sc(OTf)3 serves as an effective and practical pre-catalyst. The scope of this reaction is demonstrated with cyclization reactions and bicyclization reactions. The synthesis of the target compounds (terpenoid derivatives) was achieved using geraniol derivatives as intermediates. The title compounds thus formed included a quinoline thioether derivative (I) and an isoquinoline derivative (II) and related substances, such as selenium ether derivatives
Chemical Science published new progress about Bicyclic compounds Role: SPN (Synthetic Preparation), PREP (Preparation). 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Formula: C9H9NO2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts