Bao, Wen published the artcileCopper-catalyzed cyclization of 2-cyanobenzaldehydes and 2-isocyanoacetates: an efficient strategy for the synthesis of substituted 1-aminoisoquinolines, HPLC of Formula: 1013112-48-5, the main research area is cyanobenzaldehyde formylbenzonitrile cyclization isocyanoacetate copper catalyst; aminoisoquinoline isoquinolinamine preparation.
A Cu(acac)2-catalyzed cyclization reaction of 2-cyanobenzaldehydes with 2-isocyanoacetates was successfully developed providing an efficient strategy for the synthesis of substituted 1-aminoisoquinolines I (R1 = H, 6-Cl, 7-F, 8-MeO, etc.; R2 = CO2Et, CO2Me, CO2Bu-t). The reaction proceeded smoothly under mild conditions with high efficiency, and provides an alternative strategy for the synthesis of 1-aminoisoquinoline containing mols.
Chemical Communications (Cambridge, United Kingdom) published new progress about Aromatic nitriles Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 1013112-48-5 belongs to class nitriles-buliding-blocks, name is 2-Formyl-4,5-dimethoxybenzonitrile, and the molecular formula is C10H9NO3, HPLC of Formula: 1013112-48-5.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts