Grytsai, Oleksandr published the artcileArylbiamidines: synthesis and structural studies en route to anticancer applications, Product Details of C6H4N2, the main research area is thiazolyl bromophenyl biamidine synthesis anticancer.
Biamidines are a unique and poorly studied class of nitrogenous compounds prone to tautomerization and H-bonding. Four series of heteroaryl diarylbiamidines were synthesized and the antimelanoma activity and physicochem. properties of the resulting 37 new compounds were evaluated. The dimethylthiazolyl 3-bromophenyl biamidine derivative B6 (I) inhibits the growth of six different melanoma cell lines, having higher activity than the pos. control drug, the B-RAF inhibitor PLX4032. This study introduces diarylbiamidines as promising frameworks for drug discovery.
New Journal of Chemistry published new progress about Addition reaction (addition reaction of thiazolylguanidines onto aryl nitriles). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Product Details of C6H4N2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts