Reidl, Tyler W. published the artcileLewis Basic Salt-Promoted Organosilane Coupling Reactions with Aromatic Electrophiles, Application of Phthalonitrile, the main research area is arylalkane preparation; organosilane aromatic electrophile coupling Lewis basic salt promoted.
Lewis basic salts promoted organotrimethylsilane coupling with (hetero)aryl nitriles, sulfones and chlorides as a new route to 1,1-diarylalkanes. This method combined the substrate modularity and selectivity characteristic of cross-coupling with the practicality of a base-promoted protocol. In addition, a Lewis base strategy enabled a complementary scope to existing methods, employed stable and easily prepared organosilanes and achieved selective arylation in the presence of acidic functional groups. The utility of this method was demonstrated by the synthesis of pharmaceutical analogs and its use in multicomponent reactions.
Journal of the American Chemical Society published new progress about Alkanes Role: SPN (Synthetic Preparation), PREP (Preparation) (aryl). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Application of Phthalonitrile.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts