Muthukumar, Alagesan published the artcileZn(OTf)2-catalyzed access to symmetrical and unsymmetrical bisindoles from α-keto amides, Name: 2-Aminobenzonitrile(Flakes or Chunks), the main research area is phenyl oxoamide preparation indole zirconium triflate catalyst chemoselective arylation; indolyl phenyl hydroxyamide indole zirconium triflate catalyst chemoselective arylation; bisindolyl phenyl acetamide preparation.
Zn(OTf)2-catalyzed synthesis of 3,3′-bisindolyl acetamides from α-keto amides was developed. Both aromatic α-keto amides substituted with electron-donating as well as -withdrawing groups and aliphatic α-keto amides were well tolerated to provide sym. bisindoles in moderate to excellent yields. The chemoselective bisindolylation of the keto group of α-keto amides in the presence of a simple keto functionality was successfully achieved in good yields. The transformation was further extended to the synthesis of challenging unsym. bisindoles by treating indolyl α-hydroxy amides with substituted indoles. The unsym. bisindoles were isolated in good to excellent yields.
Organic & Biomolecular Chemistry published new progress about Amides, hydroxy Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Name: 2-Aminobenzonitrile(Flakes or Chunks).
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts