Wang, Zijuan published the artcilePalladium(II)-Catalyzed Three-Component Tandem Cyclization Reaction for the One-Pot Assembly of 4-Arylquinazolines, SDS of cas: 1885-29-6, the main research area is quinazoline aryl preparation; aminobenzonitrile boronic acid triethyl orthocarboxylate tandem heterocyclization palladium catalyst.
A one-pot method for joining three sep. components leading to an assortment of 4-arylquinazolines I (R1 = H, 6-Cl, 7-Cl, 8-Cl, 6-Me, 6-Br; R2 = H, Me, Ph; R3 = C6H5, 4-ClC6H4, 4-CH3C6H4, etc.) in good to excellent yields is described. The method consists of a palladium(II)-catalyzed cascade reaction involving C(sp)-C(sp2) coupling followed by intramol. C-N bond formation. The reaction was readily scaled up to gram quantity and successfully applied to the synthesis of a translocator protein (TSPO) ligand II.
Synthesis published new progress about Boronic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, SDS of cas: 1885-29-6.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts