Thirukovela, Narasimha Swamy published the artcileActivation of nitriles by silver(I) N-heterocyclic carbenes: An efficient on-water synthesis of primary amides, Synthetic Route of 100-70-9, the main research area is silver NHC catalyst preparation; nitrile silver NHC catalyst hydration; primary amide preparation.
A first example of silver(I) N-heterocyclic carbene (Ag(I)-NHC) catalyzed on-water synthesis of primary amides by hydration of nitriles under mild reaction conditions was described. This organometallic catalytic system has excellent tolerance for various homo-aromatic, hetero-aromatic and aliphatic nitriles to afford primary amides in good yields in neat water.
Tetrahedron published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Synthetic Route of 100-70-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts