Liu, Qingjie’s team published research in ChemistrySelect in 2022-06-13 | CAS: 1885-29-6

ChemistrySelect published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Product Details of C7H6N2.

Liu, Qingjie published the artcileH2O2-Promoted Inter- and Intramolecular C-N Bond Formation: Synthesis of Quinazoline Derivatives, Product Details of C7H6N2, the main research area is quinazoline preparation one pot; aminobenzylamine aldehyde benzyl bromide toluene nucleophilic amination.

Hydrogen peroxide, a cheap and easily available green oxidant, can not only produce oxygen, but also produce hydroxyl radical by homogenization under the catalysis of metal. Toluene and benzyl halide can be oxidized to benzaldehyde by hydrogen peroxide and participate in the reaction with 2-aminobenzylamine. Through the construction of C-N bond, a series of quinazoline derivatives were synthesized. This reaction allows a broad range of substrates as well as good functional group compatibility.

ChemistrySelect published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Product Details of C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts