Yang, Li published the artcileElectrochemically induced synthesis of quinazolinones via cathode hydration of o-aminobenzonitriles in aqueous solutions, Formula: C7H6N2, the main research area is quinazolinone green preparation; aldehyde aminobenzonitrile electrochem hydrolysis.
An efficient and practical electrochem. catalyzed transition metal-free process for the synthesis of substituted quinazolinones I [R1 = H, 8-Me, 6-OMe, etc.; R2 = Ph, Bn, 2-thienyl, etc.] from simple and readily available o-aminobenzonitriles and aldehydes in water has been accomplished. I2/base and water played an unprecedented and vital role in the reaction. By electrochem. catalyzed hydrolysis of o-aminobenzonitriles, the synthesis of quinazolinones with benzaldehyde was first proposed. The synthetic utility of this method was demonstrated by gram-scale operation, as well as the preparation of bioactive N-(2,5-dichlorophenyl)-6-(2,2,2-trifluoroethoxy) pteridin-4-amine, which enabled straightforward, practical and environmentally benign quinazolinone formation.
Organic & Biomolecular Chemistry published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Formula: C7H6N2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts