Coskun, Necdet published the artcileDirect conversion of aldehydes to nitriles via O-phenylcarbamoylated aldoximes, Synthetic Route of 5653-62-3, the main research area is aldehyde conversion nitrile; phenylcarbamoylated aldoxime preparation conversion nitrile; nitrile preparation.
O-arylcarbamoylated hydroxylamine tosylate reacts with aldehydes at room temperature to give the corresponding O-carbamoylated oximes. The reaction of carbamoylated hydroxylamine with aromatic aldehydes in THF or in toluene at reflux affords the corresponding nitriles and anilinium tosylate in high yield. Attempts to cyclize the O-carbamoylated oximes in the presence of AcCl lead again to the formation of nitriles.
Tetrahedron published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Synthetic Route of 5653-62-3.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts