Category: 1194-02-1

《Efficient Co-Catalyzed Double Hydroboration of Nitriles: Application to One-Pot Conversion of Nitriles to Aldimines》 was written by Gudun, Kristina A.; Slamova, Ainur; Hayrapetyan, Davit; Khalimon, Andrey Y.. Product Details of 1194-02-1 And the article was included in Chemistry – A European Journal in 2020. The article conveys some information:

The com. available and bench-stable Co(acac)2/dpephos system was employed as a precatalyst for selective and efficient room temperature hydroboration of organic nitriles with HBPin to produce a series of N,N-diborylamines [RN(BPin)2], which reacted in-situ with aldehydes to give aldimines. Formation of aldimines from N,N-diborylamines does not require a dehydrating agent, is applicable to a wide range of N,N-diborylamine and aldehyde substrates and is highly chemoselective, being unaffected by various common functional groups, such as alkenes, alkynes, secondary amines, ketones, esters, amides, carboxylic acids, pyridines, nitriles, and nitro compounds The overall transformation represents a synthetically valuable approach to aldimines from nitriles and can be performed in a sequential one-pot manner, tolerating ester, lactone, carboxamide and unactivated alkene functionalities. In the part of experimental materials, we found many familiar compounds, such as 4-Fluorobenzonitrile(cas: 1194-02-1Product Details of 1194-02-1)

4-Fluorobenzonitrile(cas: 1194-02-1) is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.Product Details of 1194-02-1

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

The author of 《A Transition-Metal-Free One-Pot Cascade Process for Transformation of Primary Alcohols (RCH2OH) to Nitriles (RCN) Mediated by SO2F2》 were Jiang, Ying; Sun, Bing; Fang, Wan-Yin; Qin, Hua-Li. And the article was published in European Journal of Organic Chemistry in 2019. SDS of cas: 1194-02-1 The author mentioned the following in the article:

Primary (benzylic) alcs. underwent transition-metal-free one-pot cascade process with SO2F2, K2CO3, and NH2OH·HCl in DMSO to yield nitriles without introducing an addnl. carbon atom. In the part of experimental materials, we found many familiar compounds, such as 4-Fluorobenzonitrile(cas: 1194-02-1SDS of cas: 1194-02-1)

4-Fluorobenzonitrile(cas: 1194-02-1) is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.SDS of cas: 1194-02-1

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

COA of Formula: C7H4FNIn 2019 ,《Selective synthesis of secondary amines from nitriles by a user-friendly cobalt catalyst》 was published in Advanced Synthesis & Catalysis. The article was written by Sharma, Dipesh M.; Punji, Benudhar. The article contains the following contents:

A simple, inexpensive and user-friendly cobalt-catalyzed method for the selective and practical synthesis of sym. and unsym. secondary amines RCH2NR1R2 [R = Pr, Ph, Bn, etc.; R1 = H, Me, Et; R2 = N-morpholinyl, Ph, 4-pyridyl, etc.] was developed via reductive amination of nitriles. The use of (xantphos)CoCl2 and ammonia borane (NH3-BH3) combination afforded the selective reduction of nitriles to sym. secondary amines, whereas the employment of (xantphos)CoCl2 and dimethylamine borane along with external amines produced unsym. secondary amines and tertiary amines. The reaction tolerated diverse functionalities, such as alkyl, alkyl ether, halides and heteroarenes. The results came from multiple reactions, including the reaction of 4-Fluorobenzonitrile(cas: 1194-02-1COA of Formula: C7H4FN)

4-Fluorobenzonitrile(cas: 1194-02-1) is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.COA of Formula: C7H4FN

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

《Lewis acid promoted dehydration of amides to nitriles catalyzed by [PSiP]-pincer iron hydrides》 was written by Chang, Guoliang; Li, Xiaoyan; Zhang, Peng; Yang, Wenjing; Li, Kai; Wang, Yajie; Sun, Hongjian; Fuhr, Olaf; Fenske, Dieter. HPLC of Formula: 1194-02-1 And the article was included in Applied Organometallic Chemistry in 2020. The article conveys some information:

The dehydration of primary amides to their corresponding nitriles using four [PSiP]-pincer hydrido iron complexes [(2-Ph2PC6H4)2MeSiFe(H)(PMe3)2, (2-Ph2PC6H4)2HSiFe(H)(PMe3)2, (2-(iPr)2PC6H4)2HSiFe(H)(PMe3)2 and (2-(iPr)2PC6H4)2MeSiFe(H)(PMe3)2] as catalysts in the presence of (EtO)3SiH as dehydrating reagent was explored in the good to excellent yields. It was proved for the first time that Lewis acid could significantly promote this catalytic system under milder reaction conditions than other Lewis acid-promoted system, such as shorter reaction time or lower reaction temperature This was also the first example that dehydration of primary amides to nitriles RCN [R = 4-ClC6H4, 2-thienyl, Bn, etc.] was catalyzed by silyl hydrido iron complexes bearing [PSiP]-pincer ligands with Lewis acid as additive. This catalytic system had good tolerance for many substituents. Among the four iron hydrides (2-Ph2PC6H4)2MeSiFe(H)(PMe3)2 was the best catalyst. The effects of substituents of the [PSiP]-pincer ligands on the catalytic activity of the iron hydrides were discussed. A catalytic reaction mechanism was proposed. Complex (2-(iPr)2PC6H4)2MeSiFe(H)(PMe3)2 was a new iron complex and was fully characterized. The mol. structure of complex (2-(iPr)2PC6H4)2MeSiFe(H)(PMe3)2 was determined by single crystal X-ray diffraction.4-Fluorobenzonitrile(cas: 1194-02-1HPLC of Formula: 1194-02-1) was used in this study.

4-Fluorobenzonitrile(cas: 1194-02-1) is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.HPLC of Formula: 1194-02-1

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

《Synergetic Covalent and Spatial Confinement of Sulfur Species by Phthalazinone-Containing Covalent Triazine Frameworks for Ultrahigh Performance of Li-S Batteries》 was written by Guan, Ruiteng; Zhong, Lei; Wang, Shuanjin; Han, Dongmei; Xiao, Min; Sun, Luyi; Meng, Yuezhong. Recommanded Product: 1194-02-1 And the article was included in ACS Applied Materials & Interfaces in 2020. The article conveys some information:

Lithium-sulfur (Li-S) batteries severely suffer from the shuttling of soluble polysulfides intermediates, insulation of sulfur and lithium sulfides, and volumetric expansion of sulfur electrodes, which result in the fast capacity decay and low utilization of active materials. To overcome these issues, a new type of porous phthalazinone-based covalent triazine frameworks (P-CTFs) with inherent N and O atoms has been in situ grown onto conductive reduced graphene oxide (rGO) by the sulfur-mediated cyclization of dinitrile monomers to afford the S/P-CTF@rGO hybrids. The well-designed structure endows the S/P-CTF@rGO composites with several features for enhanced Li-S batteries: (i) the nanoporous structure can spatially trap the sulfur species within the P-CTFs; (ii) the covalent binding of sulfur and polar groups of phthalazinone and triazine in P-CTFs exhibits strong chem. attachment and adsorption with polysulfides and further limits the diffusion of polysulfides; (iii) the conductive rGO and semiconductive P-CTFs help faster electronic transportation and accelerate the electrochem. process. Therefore, the S/P-CTF@rGO cathodes show greatly enhanced electrochem. performances with a high initial specific capacity of 1130 mAh g-1 at 0.5C and a good capacity retention of 81.4% after 500 cycles, indicating only 0.04% degradation per cycle. In the experimental materials used by the author, we found 4-Fluorobenzonitrile(cas: 1194-02-1Recommanded Product: 1194-02-1)

4-Fluorobenzonitrile(cas: 1194-02-1) is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.Recommanded Product: 1194-02-1

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

In 2019,Journal of Organic Chemistry included an article by Timelthaler, Daniel; Topf, Christoph. SDS of cas: 1194-02-1. The article was titled 《Liquid-Phase Hydrogenation of Nitriles to Amines Facilitated by a Co(II)/Zn(0) Pair: A Ligand-Free Catalytic Protocol》. The information in the text is summarized as follows:

The given report introduces a simple and user-friendly in situ method for the production of catalytically active cobalt particles. The approach circumvents the use of air- and moisture-sensitive reductants as well as the application of anhydrous Co-precursor salts. Accordingly, the described catalytic system is readily assembled under open-flask conditions by simply combining the components in the reaction vessel. Therefore, the arduous charging procedure of the reaction autoclave in a glovebox under an inert gas atm. is no longer necessary. In fact, the catalytically active material is obtained upon treatment of readily available Co(OAc)2·4 H2O with benign com. Zn powder. The catalytic performance of the resultant material was tested in the heterogeneous hydrogenation of nitriles to the corresponding primary amines. Both activity and selectivity of the cobalt catalyst are significantly enhanced if a triflate-based Lewis acid and ammonia is added to the reaction mixture The results came from multiple reactions, including the reaction of 4-Fluorobenzonitrile(cas: 1194-02-1SDS of cas: 1194-02-1)

4-Fluorobenzonitrile(cas: 1194-02-1) is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.SDS of cas: 1194-02-1

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

In 2022,Nishida, Yoshihide; Sato, Katsutoshi; Chaudhari, Chandan; Yamada, Hiroshi; Toriyama, Takaaki; Yamamoto, Tomokazu; Matsumura, Syo; Aspera, Susan Menez; Nakanishi, Hiroshi; Haneda, Masaaki; Nagaoka, Katsutoshi published an article in Catalysis Science & Technology. The title of the article was 《Nitrile hydrogenation to secondary amines under ambient conditions over palladium-platinum random alloy nanoparticles》.Synthetic Route of C7H4FN The author mentioned the following in the article:

Bimetalization between palladium (Pd) and platinum (Pt) nanoparticles, which resulted in a catalyst that showed high yield of secondary amines. Although Pd and Pt were thermodynamically immiscible, successfully alloyed the two metals by means of rapid chem. reduction assisted by microwave heating. X-ray absorption spectroscopy suggested the formation of heteroat. Pdδ+Ptδ- sites via charge transfer between neighboring Pd and Pt atoms in the alloy structure. Moreover, Fourier transform IR spectroscopy and scanning transmission electron microscopy-energy-dispersive X-ray spectroscopy indicated that decreasing the size of the PdPt (50 : 50) nanoparticles improved the degree of alloying and facilitated the formation of electron-enriched Ptδ- species. On the basis of kinetics studies and d. functional theory calculations, that cyano group activation, which was the rate-determining step over monometallic Pd and Pt catalysts, was accelerated over the heteroat. Pdδ+Ptδ- sites because of strong back-donation from electron-enriched Ptδ- species to the carbon atom of the cyano groups. The PdPt random alloy nanoparticles catalyzed the reactions of various aromatic and heterocyclic nitriles, and the corresponding secondary amines were selectively obtained in just a few hours. In addition to this study using 4-Fluorobenzonitrile, there are many other studies that have used 4-Fluorobenzonitrile(cas: 1194-02-1Synthetic Route of C7H4FN) was used in this study.

4-Fluorobenzonitrile(cas: 1194-02-1) is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.Synthetic Route of C7H4FN

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

In 2022,Luo, Yan; Li, Min; Tang, Jiaqi; Zang, Jianyang; Wang, Yonggang; Liu, Taihong; Fang, Yu published an article in Journal of Colloid and Interface Science. The title of the article was 《Interfacially confined preparation of fumaronitrile-based nanofilms exhibiting broadband saturable absorption properties》.Formula: C7H4FN The author mentioned the following in the article:

Interfacial nanofilms with nonlinear optical (NLO) properties were prepared via confined dynamic condensation of 4,4′-methylenedianiline (MDA) with the synthesized 2,3-bis(4-(bis(4-formylphenyl)amino)phenyl)fumaronitrile (BTFA). Investigated using the open-aperture Z-scan technique, BTFA showed reverse saturable absorption ascribed to the synergetic mechanisms of two-photon and excited-state absorption. In contrast, the as-prepared nanofilms demonstrated broadband saturable absorption within the spectral range of 720-1700 nm. The characteristics of nonlinear absorption coefficient (β) decreased along with increasing the incident pulse intensity. Taking advantage of the flexibility and post-machinability properties, the folding layers of the nanofilms offered the feasibility to fine-tune the specific NLO responses. The optimal β value was found to be -10.1 cm/MW for eight-layer nanofilm as well as the normalized transmittance increased up to 35-fold at 800 nm. Utilized as a conceptual saturable absorber, the representative modulation depth and saturation intensity were observed to be around 2.4% and 7.37 GW/cm2 at 800 nm, resp., comparable to traditional two-dimensional (2D) materials. Aiming to clarify the possible underlying phys. processes, a four-level model was employed to illustrate the fast relaxation of the excited states. Present work demonstrates that proper design of building blocks combined with interfacially confined dynamic condensation enables rational development of high-performance NLO materials. In the experiment, the researchers used many compounds, for example, 4-Fluorobenzonitrile(cas: 1194-02-1Formula: C7H4FN)

4-Fluorobenzonitrile(cas: 1194-02-1) is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.Formula: C7H4FN

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

In 2022,Zeynizadeh, Behzad; Mousavi, Hossein; Mohammad Aminzadeh, Farkhondeh published an article in Journal of Molecular Structure. The title of the article was 《A hassle-free and cost-effective transfer hydrogenation strategy for the chemoselective reduction of arylnitriles to primary amines through in situ-generated nickel (II) dihydride intermediate in water》.Application In Synthesis of 4-Fluorobenzonitrile The author mentioned the following in the article:

A new, simple, efficient, inexpensive, and chemoselective transfer hydrogenation strategy was introduced for the straightforward reduction of arylnitriles to corresponding primary amines using sodium borohydride (NaBH4) and nickel acetate tetrahydrate (Ni(OAc)2•4H2O) through in situ-generated nickel (II) dihydride intermediate in the water medium at 50°. The presented methodol. featured moderate reaction conditions, nickel boride (Ni2B)-free trajectory, good-to-excellent yields of the products, relatively short reaction times, satisfactory chemoselectivity, and did not involve the use of toxic organic solvent and also any base or ligand. In the experiment, the researchers used 4-Fluorobenzonitrile(cas: 1194-02-1Application In Synthesis of 4-Fluorobenzonitrile)

4-Fluorobenzonitrile(cas: 1194-02-1) is used in the synthesis of flurenones, pharmaceutical prerequisites, as well as opiod receptor antagonists.Application In Synthesis of 4-Fluorobenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

《High-Performance Ultraviolet Organic Light-Emitting Diode Enabled by High-Lying Reverse Intersystem Crossing》 was written by Zhang, Han; Li, Ganggang; Guo, Xiaomin; Zhang, Kai; Zhang, Bing; Guo, Xuecheng; Li, Yuxuan; Fan, Jianzhong; Wang, Zhiming; Ma, Dongge; Tang, Ben Zhong. Formula: C7H4FNThis research focused onUV organic emitter light emitting diode color purity; OLEDs; UV emission; hybridized local and charge-transfer state; record-high EQE; reverse intersystem crossing. The article conveys some information:

UV organic emitters that can open up applications for future organic light-emitting diodes (OLEDs) are of great value but rarely developed. Here, we report a high-quality UV emitter with hybridized local and charge-transfer (HLCT) excited state and its application in UV OLEDs. The UV emitter, 2BuCz-CNCz, shows the features of low-lying locally excited (LE) emissive state and high-lying reverse intersystem crossing (hRISC) process, which helps to balance the color purity and exciton utilization of UV OLED. Consequently, the OLED based on 2BuCz-CNCz exhibits not only a desired narrowband UV electroluminescent (EL) at 396 nm with satisfactory color purity (CIEx, y=0.161, 0.031), but also a record-high maximum external quantum efficiency (EQE) of 10.79 % with small efficiency roll-off. The state-of-the-art device performance can inspire the design of UV emitters, and pave a way for the further development of high-performance UV OLEDs. In the part of experimental materials, we found many familiar compounds, such as 4-Fluorobenzonitrile(cas: 1194-02-1Formula: C7H4FN)

4-Fluorobenzonitrile(cas: 1194-02-1) is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.Formula: C7H4FN

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts