Category: 1885-29-6

Kooijman, Pieter C. published the artcileA novel dual ionization modality source for infrared laser ablation post-ionization mass spectrometry imaging to study fungicide metabolism and transport, Computed Properties of 1885-29-6, the main research area is ionization modality IR laser ablation postionization MSI fungicide metabolism.

We present a novel probe design for ambient laser-based mass spectrometry imaging combining electrospray ionization (ESI) and atm. pressure chem. ionization (APCI) in a single probe, compatible with a com. laser ablation electrospray ionization (LAESI) instrument. Here we describe the probe design considerations and features, as well as an inhouse developed data processing routine designed to extract accurate mass spectrometry imaging data from ambient laser ablation post-ionization experiments We characterize the probe performance in both APCI and ESI mode on a selection of compounds and show improved pixel-to-pixel repeatability for LA-APCI as compared to LAESI. We apply the dual ionization probe in APCI mode in a time series experiment to monitor agrochems. on tomato plants. We investigate the translocation of fungicide isotianil and one of its metabolites, anthranilonitrile, by mass spectrometry imaging over a period of two weeks after application on a leaf surface. LA-APCI-MSI shows translocation of anthranilonitrile from treated leaves towards non-treated leaves. In summary, we demonstrate that LA-APCI imaging is a valuable addition to the ambient mass spectrometry toolbox, with particular advantages for imaging experiments across a variety of compounds

International Journal of Mass Spectrometry published new progress about Atmospheric pressure chemical ionization mass spectrometry. 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Computed Properties of 1885-29-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nasibipour, Mina published the artcileTuning of the redox potential and catalytic activity of a new Cu(II) complex by o-iminobenzosemiquinone as an electron-reservoir ligand, Application of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is preparation crystal mol structure copper iminobenzosemiquinone complex; EPR spectra magnetic property copper iminobenzosemiquinone complex; cyclic voltammetry copper iminobenzosemiquinone complex; alc oxidation catalyst copper iminobenzosemiquinone complex; homocoupling catalyst copper iminobenzosemiquinone complex.

The synthesis and characterization of a new Cu(II) complex, LNIS2CuII (LNIS = o-iminobenzosemiquinone), are reported. X-ray crystallog. studies showed that two o-iminobenzosemiquinone radicals form a distorted square-planar geometry around the Cu(II) center of LNIS2CuII. Magnetic measurements revealed the paramagnetic character of the complex caused by the presence of three unpaired electrons located on the o-iminobenzosemiquinonate ligands and the CuII center. Magnetochem. experiments, and EPR and DFT studies prove that the ground state of the complex is a doublet, which is consistent with the ferromagnetic coupling between Cu(II) and o-iminobenzosemiquinone centers and stronger antiferromagnetic coupling between the iminobenzosemiquinone moieties. The ligand-centered redox reactions of the complex were studied by cyclic voltammetry. Aerobic oxidation of alcs. to aldehydes with TEMPO was studied in the presence of LNIS2CuII. Furthermore, LNIS2CuII is an efficient catalyst in homo-coupling of terminal alkynes.

New Journal of Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Application of 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Zhang, Xinyu published the artcileUse of trifluoroacetaldehyde N-tfsylhydrazone as a trifluorodiazoethane surrogate and its synthetic applications, Formula: C7H6N2, the main research area is thiol trifluorodiazoethane iron porphyrin catalyst difluoroalkenylation; alc trifluorodiazoethane iron porphyrin catalyst difluoroalkenylation; amine trifluorodiazoethane iron porphyrin catalyst difluoroalkenylation; unsaturated compound trifluorodiazoethane iron porphyrin catalyst Doyle Kirmse reaction; alkene trifluorodiazoethane iron porphyrin catalyst diastereoselective cyclopropanation.

The development of trifluoroacetaldehyde N-tfsylhydrazone (TFHZ-Tfs) as a CF3CHN2 surrogate, which was capable of generating CF3CHN2 in-situ under basic conditions was reported. The reaction conditions employed in this chem. enabled a difluoroalkenylation of X-H bonds (X = N, O, S, Se), affording a wide range of heteroatom-substituted gem-difluoroalkenes, along with Doyle-Kirmse rearrangements and trifluoromethylcyclopropanation reactions, with superior outcomes to approaches using pre-formed CF3CHN2. Given the importance of generally applicable fluorination methodologies, the use of TFHZ-Tfs thus creates opportunities across organic and medicinal chem., by enabling the wider exploration of the reactivity of trifluorodiazoethane.

Nature Communications published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Formula: C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Yamaguchi, Eiji published the artcileOlefin Bifunctionalization: A Visible-light Photoredox-catalyzed Aryl Alkoxylation of Olefins, Product Details of C7H6N2, the main research area is diarylethyl ether photochem preparation; ruthenium photoredox catalyst arylalkoxylation aryl alkene diazonium salt alc; photochem arylalkoxylation aryl alkene diazonium salt alc; alkoxylation; bifunctionalization; olefins; photoredox catalyst; visible light.

Aryl alkenes such as RCH:CH2 (R = Ph, 4-MeCOC6H4, 4-MeO2CC6H4, 4-BrC6H4, 4-ClC6H4, 4-MeC6H4, 3-MeC6H4, 2-MeC6H4, 4-MeC6H4, 1-naphthyl, 2-naphthyl) underwent photoredox arylalkoxylation under visible light with aryldiazonium tetrafluoroborates such as R1N2+BF4- (R1 = 4-O2NC6H4, 3-O2NC6H4, 4-MeCOC6H4, 4-MeO2CC6H4, 4-NCC6H4, 3-NCC6H4, 2-NCC6H4, 4-F3CC6H4, 3-BrC6H4, 2-BrC6H4, 4-ClC6H4, 4-FC6H4) and methanol, ethanol, or 1-propanol in acetonitrile/alc. mixtures in the presence of Ru(bpy)3Cl2 to yield diarylethyl ethers such as R1CH2CH(OMe)R (R = Ph, 4-MeCOC6H4, 4-MeO2CC6H4, 4-BrC6H4, 4-ClC6H4, 4-MeC6H4, 3-MeC6H4, 2-MeC6H4, 4-MeC6H4, 1-naphthyl, 2-naphthyl; R1 = 4-O2NC6H4, 3-O2NC6H4, 4-MeCOC6H4, 4-MeO2CC6H4, 4-NCC6H4, 3-NCC6H4, 2-NCC6H4, 4-F3CC6H4, 3-BrC6H4, 2-BrC6H4, 4-ClC6H4, 4-FC6H4).

Chemistry – An Asian Journal published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Product Details of C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Yamaguchi, Eiji published the artcileRuthenium polypyridyl complex-catalyzed aryl alkoxylation of styrenes: improving reactivity using a continuous flow photo-microreactor, Related Products of nitriles-buliding-blocks, the main research area is diarylethyl ether preparation photochem; styrene aryldiazonium tetrafluoroborate alc alkoxylation ruthenium polypyridyl complex catalyst.

In this report, an improved protocol for the synthesis of diarylethyl ethers R1C6H4CH2CH(R2)C6H4R3 [R1 = H, 4-Me, 2-CN, etc.; R2 = OMe, OEt, OiPr, OBn, OC(O)H; R3 = 2-Me, 4-MeO, 4-tBu, etc.] via ruthenium polypyridyl complex catalyzed aryl alkoxylation of styrenes with aryldiazonium tetrafluoroborates and alcs. using continuous flow photo-microreactor was described.

Reaction Chemistry & Engineering published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Related Products of nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Liu, Qingjie published the artcileH2O2-Promoted Inter- and Intramolecular C-N Bond Formation: Synthesis of Quinazoline Derivatives, Product Details of C7H6N2, the main research area is quinazoline preparation one pot; aminobenzylamine aldehyde benzyl bromide toluene nucleophilic amination.

Hydrogen peroxide, a cheap and easily available green oxidant, can not only produce oxygen, but also produce hydroxyl radical by homogenization under the catalysis of metal. Toluene and benzyl halide can be oxidized to benzaldehyde by hydrogen peroxide and participate in the reaction with 2-aminobenzylamine. Through the construction of C-N bond, a series of quinazoline derivatives were synthesized. This reaction allows a broad range of substrates as well as good functional group compatibility.

ChemistrySelect published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Product Details of C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Liu, Lin published the artcileCopper-Catalyzed Intermolecular Enantioselective Radical Oxidative C(sp3)-H/C(sp)-H Cross-Coupling with Rationally Designed Oxazoline-Derived N,N,P(O)-Ligands, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks), the main research area is cycloalkene alkyne copper catalyst regioselective enantioselective oxidative cross coupling; cycloalkenyl alkyne preparation; alkyne aryl alkene copper catalyst enantioselective oxidative cross coupling; aryl alkyne preparation regioselective; alkynylation; anionic N,N,P(O)-ligands; copper catalysis; oxidative cross-coupling; radical asymmetric chemistry.

Here, a copper-catalyzed asym. C(sp3)-C(sp) cross-coupling of (hetero)benzylic and (cyclic)allylic C-H bonds with terminal alkynes that occurs with high to excellent enantioselectivity was reported. Critical to the success is the rational design of chiral oxazoline-derived N,N,P(O)-ligands that not only tolerate the strong oxidative conditions which were requisite for intermol. hydrogen atom abstraction (HAA) processes but also induce the challenging enantiocontrol. Direct access to a range of synthetically useful chiral benzylic alkynes and 1,4-enynes, high site-selectivity among similar C(sp3)-H bonds, and facile synthesis of enantioenriched medicinally relevant compounds make this approach very attractive.

Angewandte Chemie, International Edition published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Fan, Pei published the artcileNickel/Photo-Cocatalyzed Asymmetric Acyl-Carbamoylation of Alkenes, Safety of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is nickel photo cocatalyst asym acylcarbamoylation alkene carbamic chloride; stereoselective indolinone preparation.

An unprecedented asym. acyl-carbamoylation of pendant alkenes tethered on aryl carbamic chlorides with both aliphatic and aromatic aldehydes has been developed via the cooperative catalysis of a chiral nickel-PHOX complex and tetrabutylammonium decatungstate. This reaction represents the first example of merging hydrogen-atom-transfer photochem. and asym. transition metal catalysis in difunctionalization of alkenes. Using this protocol, a variety of oxindoles bearing a challenging quaternary stereogenic center are furnished under mild conditions in highly enantioselective manner.

Journal of the American Chemical Society published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Safety of 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Chandra, Devesh published the artcileMicrowave-Assisted Metal-Free Rapid Synthesis of C4-Arylated Quinolines via Povarov Type Multicomponent Reaction, Application of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is aniline aldehyde alkyne camphor sulfonic acid Povarov multicomponent microwave; quinoline metal free preparation.

A rapid microwave assisted, (±) camphor-10-sulfonic acid (CSA)promoted, Povarov type multicomponent synthesis of 4-arylated quinolines fromanilines, alkynes, and paraformaldehyde is described. This reaction proceeds through[4+2] cycloaddition of imine (formed in situ from aniline and paraformaldehyde) andalkynes in the presence of CSA, without any metal catalyst. Mechanistic study revealedthat CSA inhibit the synthesis of Troger’s base and assist the cycloaddition ofimines with alkynes by activating the imine.

European Journal of Organic Chemistry published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Application of 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Gatera, Tharcisse published the artcileOne-Pot, Catalyst-Free Synthesis of Nitriles from Aldehydes Using Aminating Reagent MsONH3OTf, Related Products of nitriles-buliding-blocks, the main research area is nitrile preparation green chem; aldehyde amination.

An eco-friendly protocol to synthesize nitriles RCN (R = naphthalen-2-yl, n-hexyl, 4-bromophenyl, etc.) from their corresponding aromatic and aliphatic aldehydes RCHO in excellent yields has been developed. This is a catalyst-free protocol which employs an aminating reagent (MsONH3OTf) under mild conditions. The hydroxylamine triflic acid salts (MsONH3OTf) acted as the N source for this protocol. The protocol proved to be easy to perform and presented good functional group tolerance.

Synlett published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Related Products of nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts