Category: 1885-29-6

Hazarika, Shikharani published the artcileSilica supported spinel structured cobalt ferrite multifunctional nanocatalyst for hydration of nitriles and oxidative decarboxylation of phenylacetic acids, Application In Synthesis of 1885-29-6, the main research area is aryl aldehyde preparation green chem; phenyl acetic acid oxidative decarboxylation silica support ferrite nanocatalyst; amide preparation green chem; nitrile hydration silica support cobalt ferrite nanocatalyst.

The silica-supported cobalt ferrite spinel nanocatalyst has been successfully synthesized by the coprecipitation method and extensively characterized by FTIR, XRD, SEM-EDX, TEM, BET, VSM, XPS, TGA, and ICP-AES anal. The bands observed at 3435 cm-1 (μOH of Si-OH) and 1637 cm-1 (γOH of Si-OH) in the FTIR spectrum of the as-synthesized nanocatalyst unambiguously tell the presence of silica support. Moreover, a very weak intensity and a medium intensity peak at 683 cm-1 and 463 cm-1 suggested intrinsic stretching vibrations of Fe-O and Co-O of cobalt ferrite, resp. The XRD pattern confirms the formation of CoFe2O4 spinel. The average crystallite size was found to be 5.4 nm as calculated by using the Debye-Scherrer equation based on the (220) plane while the average particle size was found to be 5.08 nm from TEM anal. The crystalline nature of the nanocomposite was confirmed by the SAED pattern. The successful incorporation of CoFe2O4 on the surface of silica was established by the BET surface area measurements. The silica-supported cobalt ferrite nanocatalyst has been explored as a heterogeneous multifunctional catalyst for hydration of nitriles RCN (R = Ph, pyridin-3-yl, 4-cyanobutyl, etc.) and oxidative decarboxylation of phenylacetic acids R1CH2C(O)OH (R1 = Ph, 2-hydroxynaphthalen-1-yl, 2,5-dimethoxyphenyl, etc.) as well under mild reaction conditions with moderate to excellent isolated yield of the desired products (60-99%). The catalyst was magnetically recoverable within a time frame of ~90 s and reusable up to the fifth catalytic cycle without profound loss of activity. A magnetic hysteresis study was performed to elucidate the magnetic behavior of the catalyst. The saturation magnetization value of 39.785 emu/g with a coercivity value of 110.87 Oe and saturation remanence value of 5.185 emu/g clearly indicated the presence of a ferromagnetic component in the material.

Applied Organometallic Chemistry published new progress about Aromatic amides Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Application In Synthesis of 1885-29-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Du, Jialei published the artcileCommercially Available CuO Catalyzed Hydrogenation of Nitroarenes Using Ammonia Borane as a Hydrogen Source, Product Details of C7H6N2, the main research area is nitroarene ammonia borane copper oxide catalyst hydrogenation; arylamine preparation.

The com. available CuO powder was demonstrated as robust catalyst for hydrogenation of nitroarenes using ammonia borane as a hydrogen source under mild conditions. Numerous amines (even sterically hindered, halogenated, and diamines) were obtained through this method. This monometallic catalyst is characteristic of support-free, excellent chemoselectivity, low-cost, and high recyclability, which will favor its future utilization in preparative reduction chem. Mechanistic studies were also carried out to clarify that diazene and azoxybenzene are key intermediates of this heterogeneous reduction

ChemCatChem published new progress about Aromatic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Product Details of C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Shuai, Qi published the artcileMetal-free chemoselective reduction of nitroaromatics to anilines via hydrogen transfer strategy, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks), the main research area is aromatic amine preparation chemoselective green chem; nitro aromatic reduction.

A novel protocol for chemoselective reduction of aromatic nitro compounds ArNO2 (Ar = Ph, 1,3-benzothiazol-6-yl, quinolin-8-yl, 4-NCC6H4, etc.) to aromatic amines ArNH2 has been established. The metal-free reduction goes through a hydrogen transfer process. Various easily reducible functional groups can be well tolerated under the optimized reaction conditions.

Chemical Papers published new progress about Aromatic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Goksu, Haydar published the artcileA Novel Hydrogenation of Nitroarene Compounds with Multi Wall Carbon Nanotube Supported Palladium/Copper Nanoparticles (PdCu@MWCNT NPs) in Aqueous Medium, Safety of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is multi wall carbon nanotube supported palladium copper nanocatalyst; aryl amine preparation; nitroarene hydrogenation palladium copper nanocatalyst.

A novel nanocatalyst, multi-wall carbon nanotube supported palladium/copper (PdCu@MWCNT) nanoparticles, was synthesized for the reduction of nitroarene compds to afford aryl amines ArNH2 [Ar = 4-MeC6H4, 3-HOC6H4, 1-naphthyl, etc.]. Characterization of the nanocatalyst was achieved by XRD, XPS, TEM, and Raman spectroscopy anal. In this study, the hydrogenation of nitroarenes to primary amine compounds was achieved in aqueous medium at room temperature The aniline derivatives were synthesized with high yields at mild conditions via novel PdCu@MWCNT nanocatalyst. The conversion of nitroarenes to amine derivatives was accomplished at 99% efficiency. In addition to its high activity, the PdCu@MWCNT catalyst was determined to be stable and reusable after the 3rd consecutive use for the reaction and provided 99% conversion of various compounds in the reduction reaction.

Scientific Reports published new progress about Aromatic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Safety of 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Moghaddam, Firouz Matloubi published the artcileAn advancement in the synthesis of nano Pd@magnetic amine-Functionalized UiO-66-NH2 catalyst for cyanation and O-arylation reactions, Safety of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is palladium magnetic amine MOF UiO66 NH2 preparation thermal stability; benzonitrile preparation; phenyl aryl ether preparation.

The magnetic MOF-based catalytic system has been reported here to be an efficient catalyst for synthesis of benzonitriles and diarylethers of aryl halides under optimal conditions. The MOF catalyst was built based on magnetic nanoparticles and UiO-66-NH2 which further modified with 2,4,6-trichloro-1,3,5-triazine and 5-Ph tetrazole at the same time and the catalyst structure was confirmed by various techniques. This new modification has been applied to increase anchoring palladium into the support. Furthermore, the products’ yields were obtained in good to excellent for all reactions under mild conditions which result from superior activity of the synthesized heterogeneous catalyst containing palladium. Also, the magnetic property of the MOF-based catalyst makes it easy to sep. from reaction mediums and reuse in the next runs.

Scientific Reports published new progress about Aromatic ethers Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Safety of 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Vishwakarma, Niraj K. published the artcileConverting CO2 into heterocyclic compounds under accelerated performance through Fe3O4-grafted ionic liquid catalysts, Safety of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is heterocyclic compound preparation ferric oxide grafted ionic liquid catalyst.

Solid supported catalysts such as amines are in high demand for the chem. fixation of CO2 into commodity chems. Here, we demonstrate an accelerated platform for 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU)-ionic liquid (IL) catalyzed CO2 fixation via the grafting of DBU-ILs over magnetically separable Fe3O4 nanoparticles (MNPs). The DBU-ILs were covalently immobilized over Fe3O4 MNPs utilizing the thio-ene reaction of allyl-DBU with -SH modified Fe3O4 MNPs. The DBU-IL-grafted Fe3O4 (Fe3O4@DBU-ILs) materials were characterized by Fourier-transform IR spectroscopy, field-emission SEM, transmission electron microscopy, XPS, thermogravimetric anal. and vibrating-sample magnetometry. TEM revealed that the MNPs have a spherical structure with a particle size of 12-20 nm. VSM showed the gradual decrease in magnetization after stepwise grafting from Fe3O4 to Fe3O4@DBU-ILs. The efficacy of the two different Fe3O4@DBU-ILs, Fe3O4@[HDBU+][TFE-] and Fe3O4@[HDBU+][AcO-] prepared by neutralization of Fe3O4@DBU with 2,2,2-trifluoroethanol (TFE) and acetic acid (AcOH), was investigated by simultaneous fixation of CO2 into the important heterocyclic compounds quinazoline-2,4(1H,3H)-dione and benzimidazolone. This approach shows excellent recyclability with a nominal decrease (2-3%) in product yields after each cycle. In particular, the energy-dispersive X-ray spectroscopy mapping of Fe3O4@[HDBU+][TFE-] used for five cycles demonstrated significant leaching of TFE. Interestingly, after retreatment with TFE, Fe3O4@[HDBU+][TFE-] showed a similar yield to that of a fresh catalyst.

New Journal of Chemistry published new progress about Benzimidazoles Role: IMF (Industrial Manufacture), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Safety of 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Hu, Pengfei published the artcileQuaternary-centre-guided synthesis of complex polycyclic terpenes, Safety of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is terpene polycyclic synthesis quaternary center guided; conidiogenone synthesis quaternary center guided.

The presence of a quaternary center-a carbon with four other carbons bonded to it-in any given mol. can have a substantial chem. and biol. impact. In many cases, it can enable otherwise challenging chem. For example, quaternary centers induce large rate enhancements in cyclization reactions-known as the Thorpe-Ingold effect-which has application in drug delivery for mols. with modest bioavailability. Similarly, the addition of quaternary centers to a drug candidate can enhance both its activity and its metabolic stability. When present in chiral ligands, catalysts and auxiliaries, quaternary centers can guide reactions toward both improved and unique regio-, stereo- and/or enantioselectivity. However, owing to their distinct steric congestion and conformational restriction, the formation of quaternary centers can be achieved reliably by only a few chem. transformations. For particularly challenging cases-for example, the vicinal all-carbon8, oxa- and aza-quaternary centers9 in mols. such as azadirachtin, scopadulcic acid A and acutumine-the development of target-specific approaches as well as multiple functional-group and redox manipulations is often necessary. It is therefore desirable to establish alternative ways in which quaternary centers can pos. affect and guide synthetic planning. Here we show that if a synthesis is designed such that each quaternary center is deliberately leveraged to simplify the construction of the next-either through rate acceleration or blocking effects-then highly efficient, scalable and modular syntheses can result. This approach is illustrated using the conidiogenone family of terpenes as a representative case; however, this framework provides a distinct planning logic that is applicable to other targets of similar synthetic complexity that contain multiple quaternary centers.

Nature (London, United Kingdom) published new progress about Cyclic terpenes Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Safety of 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Wang, Menglan published the artcileIron-promoted construction of indoles via intramolecular oxidative C-N coupling of 2-alkenylanilines using persulfate, COA of Formula: C7H6N2, the main research area is indole preparation; alkenylaniline intramol oxidative coupling iron catalyst.

Without N-protection, readily prepared 2-alkenylanilines were transformed into indoles I [R1 = H, Me, 3-MeC6H4, etc.; R2 = H, Me, Et; R3 = H, 5-Me, 5-Cl] in good yields via intramol. oxidative C-N coupling using K2S2O8 as oxidant in the presence of catalytic amounts of FeF2. The K2S2O8/FeF2 system offered direct and benign synthetic route to compounds I and it is applicable to wide range of substituted indoles including drug intermediates. The advantages of this protocol were cheap reagents, no N-protection, mild conditions and good group tolerance.

Synthesis published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent) (alkenyl-). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, COA of Formula: C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Schneekoenig, Jacob published the artcileCobalt pincer complexes for catalytic reduction of nitriles to primary amines, Safety of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is nitrile cobalt pincer complex catalyst reduction; alkylamine preparation.

Various cobalt pincer type complexes I [R = iPr, Cy, Ph; X = Cl, Br] and II [X = Cl, Br] were applied for the catalytic hydrogenation of nitriles to amines. Among these, catalyst I [R = Ph, X = Cl] was the most efficient, allowing the reduction of aromatic as well as aliphatic nitriles in moderate to excellent yields.

Catalysis Science & Technology published new progress about Aralkyl amines Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Safety of 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Xiong, Hao published the artcileThe Reaction of o-Aminoacetophenone N-Tosylhydrazone and CO2 toward 1,4-Dihydro-2H-3,1-benzoxazin-2-ones, Product Details of C7H6N2, the main research area is aminoacetophenone tosylhydrazone carbon dioxide fixation carbene insertion reaction; dihydrobenzoxazinone preparation.

A transition-metal-free reaction of o-aminoacetophenone N-tosylhydrazone and CO2 has been developed, leading to a series of 1,4-dihydro-2H-3,1-benzoxazin-2-ones in moderate to good yields. This procedure proceeds with the sequential fixation of CO2 by amino leading to carbamic acid and the intra- mol. insertion of hydroxyl to carbene.

Advanced Synthesis & Catalysis published new progress about Benzoxazinones Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Product Details of C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts