Category: 20099-89-2

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Application In Synthesis of 20099-89-2.

Liu, Xiang;Song, Dan;Zhang, Zemin;Lin, Jiatong;Zhuang, Canzhan;Zhan, Haiying;Cao, Hua research published 《 Regioselective C-H dithiocarbamation of indolizines with tetraalkylthiuram disulfide under metal-free conditions》, the research content is summarized as follows. An efficient and straightforward metal-free regioselective C-H dithiocarbamation of indolizines with tetraalkylthiuram disulfide has been described. A series of indolizine-dithiocarbamate derivatives, e.g., I (R¹ = H, 8-Br, 6-Et, 7-MeO, etc., R² = Ph, 3,4-Cl₂C₆H₃, 2-furyl, etc.), were easily accessed in moderate to good yields with a broad scope. In addition, imidazo[1,2-a]pyridines II (R¹ = H, 7-Me, R² = Ph, 3-FC₆H₄, 3-MeOC₆H₄) were also well tolerated to afford diverse imidazoheterocycle-dithiocarbamate products, which are expected to be utilized for drug discovery. Of note, the reaction could be readily scaled up, and shows its practical value in organic synthesis.

Application In Synthesis of 20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Recommanded Product: 4-(2-Bromoacetyl)benzonitrile.

Kang, Xiaokang;Liang, Xiayu;Zeng, Qingle research published ã€?Water-Mediated Intramolecular Cyclization/Oxidation of α-Carbonyl Sulfur Ylides: Synthesis of Corey-Chaykovsky Reagent Type Heterocyclesã€? the research content is summarized as follows. A new class of Corey-Chaykovsky reagent type five-membered heterocycles with an oxosulfonium ylide moiety has been synthesized by the water-mediated intramol. cyclization/oxidation of α-carbonyl sulfur ylides generated in situ from sulfonium salts under mild conditions.

Recommanded Product: 4-(2-Bromoacetyl)benzonitrile, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Recommanded Product: 4-(2-Bromoacetyl)benzonitrile.

Khonde, Nilesh S.;Said, Madhukar S.;Sabane, Jagjivan K.;Gajbhiye, Jayant M.;Kumar, Pradeep research published ã€?Metal-free, Tf₂NH-catalyzed 1,6-conjugate addition of imidazopyridine to para-quinone methides: Easy access to C3-functionalized triarylmethane imidazopyridineã€? the research content is summarized as follows. An inexpensive and com. available Tf₂NH-catalyzed 1,6-conjugate addition of imidazopyridine (IMPY) heterocycles to para-quinone methides (p-QMs) were reported. The present transformation provided a diverse class of C3-functionalized triarylmethanes heterocyclic derivatives of imidazopyridine. These metal-free transformations provided a very broad substrate scope of conjugate addition product with a high yield up to 97% within a short duration.

Recommanded Product: 4-(2-Bromoacetyl)benzonitrile, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Related Products of 20099-89-2.

Kim, Beomsoo;Ahn, Seunghyun;Lee, Youngshim;Koh, Dongsoo;Lim, Yoongho research published ã€?¹H and ¹³C NMR spectral assignments of nineteen 5-(3,5-dimethoxyphenyl)-3-(2-methoxyphenyl)-2-pyrazoline derivativesã€? the research content is summarized as follows. Nineteen novel derivatives containing a pyrazolinyl-thiazole or pyrazolinyl-thiazol-4-one moiety were designed and synthesized in this study. The NMR and HR/MS data reported herein can aid in identifying similar compounds in the future.

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., Related Products of 20099-89-2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Safety of 4-(2-Bromoacetyl)benzonitrile.

Kim, Wansoo;Kim, Hun Young;Oh, Kyungsoo research published �Oxidation Potential-Guided Electrochemical Radical-Radical Cross-Coupling Approaches to 3-Sulfonylated Imidazopyridines and Indolizines� the research content is summarized as follows. Oxidation potential-guided electrochem. radical-radical cross-coupling reactions between N-heteroarenes and sodium sulfinates have been established. Thus, simple cyclic voltammetry measurement of substrates predicts the likelihood of successful radical-radical coupling reactions, allowing the simple and direct synthetic access to 3-sulfonylated imidazopyridines and indolizines. The developed electrochem. radical-radical cross-coupling reactions to sulfonylated N-heteroarenes boast the green synthetic nature of the reactions that are oxidant- and metal-free.

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., Safety of 4-(2-Bromoacetyl)benzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. COA of Formula: C9H6BrNO.

Klintworth, Robin;Morgans, Garreth L.;Scalzullo, Stefania M.;de Koning, Charles B.;van Otterlo, Willem A. L.;Michael, Joseph P. research published ã€?Silica gel and microwave-promoted synthesis of dihydropyrrolizines and tetrahydroindolizines from enaminonesã€? the research content is summarized as follows. A wide range of N-(ethoxycarbonylmethyl)enaminones I (R = 4-O₂NC₆H₄, thiophen-2-yl, tert-Bu, etc.), prepared by the Eschenmoser sulfide contraction between N-(ethoxycarbonylmethyl)pyrrolidine-2-thione and various bromomethyl aryl and heteroaryl ketones RC(O)CH₂Br, underwent cyclization in the presence of silica gel to give Et 6-(hetero)aryl-2,3-dihydro-1H-pyrrolizine-5-carboxylates II within minutes upon microwave heating in xylene at 150°C. Instead of functioning as a nucleophile, the enaminone acted as an electrophile at its carbonyl group during the cyclization. Yields of the bicyclic products II were generally above 75%. The analogous microwave-assisted reaction to produce Et 2-aryl-5,6,7,8-tetrahydroindolizine-3-carboxylates III [R¹ = Ph, 4-MeOC₆H₄,4-O₂NC₆H₄] from Et 2-[2-(2-oxo-2-arylethylidene)piperidin-1-yl]acetates IV failed in nonpolar solvents, but occurred in ethanol at lower temperature and microwave power, although requiring much longer time. A possible mechanism for the cyclization is presented, and further functionalization of the newly created pyrrole ring in the dihydropyrrolizine core was described.

COA of Formula: C9H6BrNO, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Synthetic Route of 20099-89-2.

Kokuev, Aleksandr O.;Ioffe, Sema L.;Sukhorukov, Alexey Yu. research published ã€?Addition of malonic esters to azoalkenes generated in situ from α-bromo- and α-chlorohydrazonesã€? the research content is summarized as follows. Michael addition of malonic esters to azoalkenes, generated in situ from α-bromo- and α-chlorohydrazones, has been accomplished. Both aliphatic and aromatic substrates bearing different functional groups were tolerated. The use of a strong base (sodium hydride) for generation of azoalkenes and deprotonation of malonate was found to be essential for a successful coupling. Synthetic potential of the obtained β-hydrazonoalkylmalonates RNHN:C(R¹)CH₂CH(CO₂R²)₂ [R = Ac, Boc, Cbz, 2,4-(O₂N)₂C₆H₃; R¹ = t-Bu, EtO₂C, Ph, 2-naphthyl, 2-thienyl, etc.; R² = Me, PhCH₂] was demonstrated by their smooth conversion into five- and six-membered N-heterocycles, functionalized hydrazides, 2-(2-oxo-2-arylethyl)malonates and 2-arylethylmalonates.

Synthetic Route of 20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. SDS of cas: 20099-89-2.

Jivani, A. J.;Kapadiya, K. M.;Khunt, R. C. research published ã€?Polar Solvent-Mediated Synthesis of Terminal Alkyne Derivatives of Thiazoles and Evaluation of Their Antidiabetic Activityã€? the research content is summarized as follows. Two new pharmacol. active series of N-alkyne-substituted indole-thiazoles, I [R = H, 4-NC, 4-Cl, etc.] and C-alkyne-substituted benzylidene-thiazoles, II [R¹ = 4-Me, 4-F, 4-NC, etc.] were synthesized by a two-step procedure involving initial reactions of thiosemicarbazide with, resp., [1-(prop-2-yne-1-yloxy)-1H-indol-3-yl]formaldehyde and 2-(prop-2-yne-1-yloxy)benzaldehyde, followed by the reactions of the resulting hydrazine-1-carbothioamides with a variety of substituted phenacyl bromides. In-vitro antidiabetic activity screening by the α-amylase inhibition assay with Acarbose as a reference drug revealed an excellent antidiabetic potency in four-terminal alkyne-substituted benzylidene-and indole-thiazoles derived from dichloro- and bromophenacyl bromides.

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., SDS of cas: 20099-89-2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion. Name: 4-(2-Bromoacetyl)benzonitrile.

Kang, Lei;Wang, Fang;Zhang, Jinlong;Yang, Huameng;Xia, Chungu;Qian, Jinlong;Jiang, Gaoxi research published ã€?High Chemo-/Stereoselectivity for Synthesis of Polysubstituted Monofluorinated Pyrimidyl Enol Ether Derivativesã€? the research content is summarized as follows. A novel intramol. Smiles rearrangement of α-fluoro-β-keto-pyrimidylsulfones (usually used as a carbon nucleophile) was developed, providing a versatile avenue for synthesis of tri/tetra-substituted monofluorinated pyrimidyl enol ethers. Among these, diverse (Z)-monofluorovinylsulfones and sulfinates were efficiently assembled by adding extra electrophile and fine-tuning reaction conditions. The process was triggered by a keto-enol tautomerism from enol oxyanion to pyrimidine 2-carbon, completely different from the classical carbon nucleophilic addition reaction approach.

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., Name: 4-(2-Bromoacetyl)benzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. SDS of cas: 20099-89-2.

Kang, Lei;Zhang, Jinlong;Yang, Huameng;Qian, Jinlong;Jiang, Gaoxi research published ã€?Base-Catalyzed Defluorination/O-Arylation Reaction for the Synthesis of 3-Fluoro-1,4-oxathiine 4,4-Dioxideã€? the research content is summarized as follows. A novel process involving base-catalyzed intramol. defluorination/O-arylation of readily available α-fluoro-β-one-sulfones was realized and provided a series of 3-fluoro-1,4-oxathiine 4,4-dioxide derivatives, e.g., I, in good to excellent yields. Unlike traditional defluorination reactions with stoichiometric base as the deacid reagent, this process is triggered by a catalytic amount of base (TMG: tetramethylguanidine) and mol. sieves serve as both an adsorbent to remove HF acid and an activator to assist C-F bond cleavage.

SDS of cas: 20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts