Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Synthetic Route of 31643-49-9.
Wang, Minghua;Zhu, Lei;Zhang, Shuai;Lou, Yafei;Zhao, Shuangrun;Tan, Quan;He, Linghao;Du, Miao research published 《 A copper(II) phthalocyanine-based metallo-covalent organic framework decorated with silver nanoparticle for sensitively detecting nitric oxide released from cancer cells》, the research content is summarized as follows. A novel metallo-copper phthalocyanine-based covalent-organic framework (CuTAPc-MCOF) doped with silver nanoparticles (denoted as CuTAPc-MCOF@AgNPs) was developed. CuTAPc-MCOF was synthesized using Cu(II) 4′,4′′,4′′′,4′′′′-tetra-amine phthalocyanine (CuTAPc) and 2,9-bis[p-(formyl)phenyl]-1,10-phenanthroline as building blocks through the Schiff base condensation reaction. The basic characterizations revealed that CuTAPc-MCOF demonstrated extended π-system and possessed the phenanthroline group, which can be coordinated with Ag. Consequently, it endowed the CuTAPc-MCOF@AgNPs nanohybrid with good biol. compatibility, boosted electron transfer, and produced abundant catalytic active sites. As such, the CuTAPc-MCOF@AgNPs nanohybrid illustrated superior biocompatibility and excellent electrocatalytic activity, thereby showing remarkable electrocatalytic performance for electro-oxidizing nitric oxide (NO) released from living cancer cells. The sensing properties of the CuTAPc-MCOF@AgNPs-based sensor were measured by cyclic voltammetry and amperometry techniques. The CuTAPc-MCOF@AgNPs-based electrochem. sensor showed a high sensitivity of 29.1 ΜA ΜM-1 cm-2 and a low detection limit of 12.6 nM within the concentration range of 0.18 ΜM to 17.1 ΜM toward NO, together with excellent selectivity, high reproducibility and repeatability, and good stability. Overall, our sensing strategy showed potential application in detecting NO released from living cancer cells and diagnosing biol. processes.
Synthetic Route of 31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts