Category: 484-47-9

Reference of 2,4,5-Triphenylimidazole. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 2,4,5-Triphenylimidazole, is researched, Molecular C21H16N2, CAS is 484-47-9, about One-Pot Synthesis of Polysubstituted Imidazoles Based on Pd(OAc)2/Ce(SO4)2/Bi(NO3)3 Trimetallic Cascade of Decarboxylation/Wacker-Type Oxidation/Debus-Radziszewski Reaction.

A novel and highly efficient one-pot synthesis of polysubstituted imidazoles I (R1 = H, 2-NO2, 4-Me, etc.; R2 = H, benzyl, 4-methylphenyl, etc.) from α-hydroxyphenylacetic acids R1C6H4CH(OH)CO2H, diphenylacetylene, and amines R2NH2 has been achieved by Pd(OAc)2/Ce(SO4)2/Bi(NO3)3 trimetallic catalytic system. A series of control experiments showed that this overall reaction occurs through a one-pot cascade process combining the steps of decarboxylation of α-hydroxyphenylacetic acids, Wacker-type oxidation of diphenylacetylene, and Debus-Radziszewski annulation of aryl aldehydes and benzil generated in situ, as well as amines.

Although many compounds look similar to this compound(484-47-9)Reference of 2,4,5-Triphenylimidazole, numerous studies have shown that this compound(SMILES:C1(C2=CC=CC=C2)=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

SDS of cas: 484-47-9. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 2,4,5-Triphenylimidazole, is researched, Molecular C21H16N2, CAS is 484-47-9, about One-Pot, Two-Step Metal and Acid-Free Synthesis of Trisubstituted Imidazole Derivatives via Oxidation of Internal Alkynes Using an Iodine/DMSO System. Author is Naidoo, Shivani; Jeena, Vineet.

Diaryl alkynes underwent oxidative cyclocondensation reactions with aryl aldehydes and cyclohexanecarboxaldehyde mediated by I2 and DMSO followed by with NH4OAc in EtOH to yield diaryl- and triarylimidazoles. Benzyl alc. and cyclohexanemethanol underwent oxidative cyclocondensation with diphenylacetylene using I2 and DMSO to yield a tri-Ph and a diphenylimidazole in 81% and 20% yields, resp. A mechanism for the reaction is suggested and potential intermediates prepared and reacted further.

Compounds in my other articles are similar to this one(2,4,5-Triphenylimidazole)SDS of cas: 484-47-9, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

SDS of cas: 484-47-9. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 2,4,5-Triphenylimidazole, is researched, Molecular C21H16N2, CAS is 484-47-9, about Electrical and hysteric properties of organic compound-based humidity sensor and its dualistic interactive approach to H2O molecules. Author is ur Rahman, Muneeb; Gul, Hina; ur Rahman, Zia; Zulfiqar, Syed; Khan, Rajwali; Ullah, Burhan; Ahmad, Iftikhar; Saeed, Aamer; Alamgir, Khalid; Ullah, Mateen; Fan, Jiandong.

The compound lophine, 2, 4, 5-triphenyl-1 H-imidazole, has been used to fabricate humidity sensors. The sensors were tested in different humidity environments, and at various applied frequencies. The SEM images showed inter-woven spiky needles, pores, pore-channels of diverse shapes and sizes. The H2O mols. interacted with N and NH sites in the aromatic ring of the compound and thus altered the elec. properties due to the imidazole scaffold’s electron acceptor and trifling donating nature. The conduction mechanism is based on Grotthuss hydroxide transfer and prototropic mobility. The calculated dielec. constant of the material was 1.69. In 45-95%RH limit, the device’s capacitance was increased from 11 pF to 460 pF and 7.29 pF to 18.9 pF at applied frequencies 1 kHz and 10 kHz, resp. The response/recovery time was 39/20 s, resp. The maximum hysteresis was 0.44% (at 1 kHz) and 1.09% (at 10 kHz). The R2 values (goodness of fit) 0.98 and 0.99 for chemisorbed and multi-layered physisorbed layers are close to unity and thus considered the best linear-fit. The sensors showed a strong affinity to moisture at ambient conditions with low hysteresis. Fabulous improvement in the device’s sensitivity has been noted over the reported sensitivity of devices based on ceramic materials.

Compounds in my other articles are similar to this one(2,4,5-Triphenylimidazole)SDS of cas: 484-47-9, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kumari, Mitlesh; Jain, Yachana; Yadav, Priya; Laddha, Harshita; Gupta, Ragini published the article 《Synthesis of Fe3O4-DOPA-Cu Magnetically Separable Nanocatalyst: A Versatile and Robust Catalyst for an Array of Sustainable Multicomponent Reactions under Microwave Irradiation》. Keywords: DOPA functionalized magnetite supported copper multicomponent reaction nanocatalyst microwave.They researched the compound: 2,4,5-Triphenylimidazole( cas:484-47-9 ).Computed Properties of C21H16N2. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:484-47-9) here.

Herein, we are reporting a facile route to synthesize magnetically separable copper loaded L-DOPA functionalized magnetite nanoparticles (Fe3O4-DOPA-CuNPs), which are well characterized by FT-IR, PXRD, SEM, EDAX, HRTEM, XPS, TGA and VSM techniques. This single catalyst exhibits excellent catalytic activity towards (i) synthesis of DHPMs via Biginelli reaction (ii) synthesis of imidazoles (iii) synthesis of 2-amino-4H-chromenes (iv) 1,2,3-triazole derivatives by ‘Click reaction’ under microwave irradiation (MWI). Interestingly it can be easily recovered and reused for subsequent cycles for above mentioned four important multicomponent reactions without any significant decrease in its catalytic activity.

Compounds in my other articles are similar to this one(2,4,5-Triphenylimidazole)Computed Properties of C21H16N2, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 484-47-9, is researched, Molecular C21H16N2, about Room temperature ionic liquid promoted improved and rapid synthesis of highly functionalized imidazole and evaluation of their inhibitory activity against human cancer cells, the main research direction is trisubstituted imidazole green preparation antitumor human docking SAR; tetrasubstituted imidazole green preparation antitumor human docking SAR.HPLC of Formula: 484-47-9.

In this study, the use of a 1,8-diazabicyclo [5.4.0]-undec-7-en-8-ium imidazolate ionic liquid as a catalyst as well as a green solvent for the expeditious multicomponent transformation of trisubstituted imidazoles I [Ar = Ph, 4-MeOC6H4; R = n-Bu, Ph, 2-furyl, etc.] and tetrasubstituted imidazoles II [R1 = Ph, 4-ClC6H4, 2-thienyl, etc.; R2 = n-Bu, Ph, 4-FC6H4, etc.; R3 = Ph, 4-MeOC6H4] via pseudo-four- and four-component reactions with short reaction time, excellent yield and purity of products was reported. The ionic liquid was cheap, biodegradable and could be recovered and reused for more than five consecutive cycles. The advantage of this protocol for gram-scale synthesis added to its practical applicability. Selected synthesized tetra- and trisubstituted imidazole scaffolds were screened for their in vitro antiproliferative properties against the human cancer cell lines EC-109, MCF-7, HGC-27, and PC-3. Compounds I [R = 2,6-di-ClC6H3, Ar = Ph], II [R1 = 4-ClC6H4, R2 = 4-MeC6H4, R3 = Ph] and II [R1 = 4-ClC6H4, R2 = Ph, R3 = 4-MeOC6H4] showed potent cytotoxic activity against the human breast cancer cell line PC-3, MCF-7 and HGC-27, resp.

When you point to this article, it is believed that you are also very interested in this compound(484-47-9)HPLC of Formula: 484-47-9 and due to space limitations, I can only present the most important information.

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Process Safety and Environmental Protection called Thermal hazards of benzaldehyde oxime: Based on decomposition products and kinetics analysis by adiabatic calorimeter, Author is Zhao, Xiao-Qiao; Wu, Wen-Qian; Li, Hua-bo; Guo, Zi-Chao; Chen, Wang-Hua; Chen, Li-Ping, which mentions a compound: 484-47-9, SMILESS is C1(C2=CC=CC=C2)=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N1, Molecular C21H16N2, Quality Control of 2,4,5-Triphenylimidazole.

As a self-reactive substance, benzaldehyde oxime (BO) is prone to a highly exothermic runaway reaction and thermal hazard anal. and the reaction kinetics calculation of BO have great significance. In this work, the decomposition products of BO in nitrogen atm. were identified by GC-MS and HPLC techniques. The impact of the decomposition products on the decomposition behaviors of BO were analyzed by comparison of the ARC test results of pure BO and mixture of BO and decomposition products. It was found that N-benzylidene benzylamine was the intermediate decomposition product and benzoic acid, benzamide, N-benzyl benzamide, and 2,4,5-triphenylimidazole were the final products of BO. A two-step continuous autocatalytic reaction model was established to depict the decomposition process of BO. The kinetic parameters of the model were calculated by applying the nonlinear optimization method. Finally, thermal behaviors under different process temperature were predicted based on the kinetic model, and the time to maximum rate (TMRad) was predicted as 112.04°C under 24 h, and 122.19°C of 8 h, which offer crucial safety information to optimize the safety conditions of BO during usage, storage and transportation, which minimizes the industrial disasters.

When you point to this article, it is believed that you are also very interested in this compound(484-47-9)Quality Control of 2,4,5-Triphenylimidazole and due to space limitations, I can only present the most important information.

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 484-47-9, is researched, SMILESS is C1(C2=CC=CC=C2)=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N1, Molecular C21H16N2Journal, RSC Advances called Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C-C bond cleavage, Author is Huang, Jiangkun; Luo, Lan; Xing, Naiguo; Gu, Linghui; Li, Chen; Han, Qiao; Zheng, Shilong; He, Ling, the main research direction is aryl imidazole preparation; ketone amination oxidative bond cleavage copper catalyst; aldehyde ketone amination oxidative bond cleavage copper catalyst.Formula: C21H16N2.

A one-pot synthesis, initiated by a copper salt with inorganic (NH4)2CO3 as the nitrogen source, forms divergent aryl imidazole derivatives I [R = H, Et, thiophen-2-yl, naphthalen-1-yl, 2H-1,3-benzodioxol-5-yl, etc.; R1 = Me, Et, n-Pr, Ph; Ar = 4-bromophenyl, thiophen-2-yl, 2,3-dihydro-1,4-benzodioxin-6-yl, etc.] and II [Ar1 = 1H-indol-3-yl, 2-phenyl-1H-indol-3-yl, 5-bromo-1H-indol-3-yl, etc.; Ar2 = Ph, 4-methylphenyl; R2 = Me, 4-methylphenyl; R3 = Me, Et] from ketones ArC(O)CH2R/Ar1C(O)CH2Ar2/R2C(O)(R3) via α-amination and oxidative C-C bond cleavage reactions. The approach provides a simple and rapid synthesis of imidazole derivatives I and II and has certain versatility.

As far as I know, this compound(484-47-9)Formula: C21H16N2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2,4,5-Triphenylimidazole, is researched, Molecular C21H16N2, CAS is 484-47-9, about Imidazo-Fused Isoindoles by Pd(II)/Ag(I)-Promoted Intramolecular Dehydrogenative Coupling, the main research direction is imidazoisoindoles preparation; benzylimidazole preparation palladium silver promoter intramol dehydrogenative coupling.Name: 2,4,5-Triphenylimidazole.

An effective Pd(II)/Ag(I)-promoted intramol. cross-dehydrogenative coupling (CDC) of substituted 1-benzylimidazoles under air provides, for the first time, a simple access to several functionalized imidazo[2,1-a]isoindoles, an interesting class of polycyclic heteroaromatic compounds The direct involvement of two unactivated carbon-hydrogen bonds, without any directing group, grants an elevated atom economy of the whole process.

As far as I know, this compound(484-47-9)Name: 2,4,5-Triphenylimidazole can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Product Details of 484-47-9. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 2,4,5-Triphenylimidazole, is researched, Molecular C21H16N2, CAS is 484-47-9, about Base-promoted annulation of amidoximes with alkynes: simple access to 2,4-disubstituted imidazoles.

An efficient construction of imidazole ring by Cs2CO3-promoted annulation of amidoximes RC(NH2)=NOH (R = Me, Ph, 4-methylphenyl, 4-(trifluoromethyl)phenyl, thiophen-2-yl) with terminal alkynes R1CCR2 (R1 = H, Ph, 3-methylphenyl, trimethylsilyl; R2 = H, Ph, naphthalen-2-yl, thiophen-2-yl, etc.) in DMSO has been developed. This protocol provides a simple synthetic route with high atom-utilization for the synthesis of 2,4-disubstituted imidazoles I in good yields under transition-metal-free and ligand-free conditions. Internal alkynes can also undergo the annulation to give 2,4,5-trisubstituted imidazoles I.

In addition to the literature in the link below, there is a lot of literature about this compound(2,4,5-Triphenylimidazole)Product Details of 484-47-9, illustrating the importance and wide applicability of this compound(484-47-9).

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Computed Properties of C21H16N2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 2,4,5-Triphenylimidazole, is researched, Molecular C21H16N2, CAS is 484-47-9, about NiO nanocomposites/rGO as a heterogeneous catalyst for imidazole scaffolds with applications in inhibiting the DNA binding activity. Author is Kumar, Gyanendra; Mogha, Navin Kumar; Kumar, Manish; Subodh; Masram, Dhanraj T..

Herein, we report a facile approach to synthesize a new highly versatile heterogeneous catalyst by spontaneous aerial oxidation based on nickel oxide nanocomposites immobilized on surface-functionalized reduced graphene oxide sheets. NiO nanocomposite/reduced graphene oxide (rGO-NiO-NC) is a highly efficient, cost-effective, reusable, selective, and eco-friendly nano-catalyst that does not lose any activity even after five reaction cycles. Nickel loading on the rGO-NiO nanocomposite was found to be 3.3 at%, which contributes to the effective and efficient use of rGO-NiO-NCs as a nano-catalyst for the synthesis of imidazole derivatives Consequently, a series of imidazole derivatives were synthesized, catalyzed by rGO-NiO-NCs, in 60 min with high yields (86% to 96%) under green conditions. Furthermore, the present synthetic methodol. was used for the synthesis of highly aromatic imidazole derivatives (B1-B3) whose calf thymus-DNA binding affinities suggest their superior inhibition ability to displace ethidium bromide (EB), which was further confirmed by mol. docking studies. Addnl., the green chem. matrix of the synthesis reaction was found to be very close to ideal values, such as carbon efficiency (82.32%), E-factor (0.51), atom economy (77.86%), process mass intensity (1.51), and reaction mass efficiency (66.14%).

In addition to the literature in the link below, there is a lot of literature about this compound(2,4,5-Triphenylimidazole)Computed Properties of C21H16N2, illustrating the importance and wide applicability of this compound(484-47-9).

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts