Category: 91-15-6

Moradi, Parisa published the artcileFabricated copper catalyst on biochar nanoparticles for the synthesis of tetrazoles as antimicrobial agents, Computed Properties of 91-15-6, the main research area is copper catalyst biochar nanoparticle tetrazole synthesis antimicrobial activity.

Biochar is a carbon-rich solid which its surface was covered by high d. of carbonyl, hydroxyl and carboxylic acid functional groups. In this work, biochar nanoparticles were prepared from pyrolysis of chicken manure and further a new copper catalyst was supported on its surface (Cu-TBA@biochar) as reusable and environmental biocatalyst. The structure of this catalyst has been characterized by SEM, EDS, WDX, XRD, TGA, N2 adsorption-desorption isotherms, FT-IR and AAS techniques. SEM images of this catalyst demonstrate that particle size is less than 100 nm in diameter The catalytic activity of this nanocatalyst was studied in the synthesis of tetrazole derivatives Tetrazole products were obtained in high TOF and TON values in the presence of Cu-ABA@biochar, which indicate the high efficiency of this catalyst. The biol. activity of obtained tetrazoles was screened against several Gram-pos. & Gram-neg. bacteria strains which these compounds were found to possess promising activity. This catalyst was reused for several runs without significant loss of its catalytic activity or copper leaching. Also, recovered catalyst was characterized by SEM, FT-IR, AAS and N2 adsorption-desorption isotherms. Heterogeneity and stability of this nanocatalyst was confirmed by hot filtration test and reusing of catalyst.

Polyhedron published new progress about Antimicrobial agents. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Computed Properties of 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Fernando Gomollon-Bel published the artcileShaking up industrial chemistry, Formula: C8H4N2, the main research area is review mechanochem industrial chem.

Grinding stuff is probably one of the oldest ways to run a chem. reaction. For example, in the fourth century BCE, people extracted mercury from cinnabar by grinding the mineral with vinegar in copper bowls. Later, as the chem. industry developed in the 19th century, the German chem. company, BASF, used giant mills called muhlenbetriebe to grind materials into synthetic organic dyes. Factory workers would load a ball mill′s large cylindrical drum with starting material and metal balls. The balls would grind the materials as the drum spun. One of the dyes made in these mills was Heliogen blue, an intense sapphire dye made by crumbling copper chloride and phthalonitrile. “”It is a really old example of a mechanochem. reaction, run without a solvent in a ball mill kiln,”” Martin Viertelhaus, a principal scientist at BASF, said at the “”Mechanochem. Meets Industry”” online workshop in Feb. 2021. In recent decades, Mechanochem. offers a greener way to make mols., but chemists need to scale it up for industry. Researchers at MOF Technologies work with extruders to use mechanochem. to develop new materials.

Chemical & Engineering News published new progress about Grinding (machining). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Formula: C8H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Liu, Limin published the artcileThe excited state behavior of Group IA alkaline-metal phthalocyanines revealed by photoluminescence and singlet oxygen formation, Application of Phthalonitrile, the main research area is metallophthalocyanine fluorescence excited state singlet oxygen formation; Fluorescence lifetime; Fluorescence spectra; Group IA metal phthalocyanine; Singlet oxygen formation; UV–Vis absorption.

Group IA alk.-metal phthalocyanine (Pc) complexes (Li2Pc, Na2Pc, K2Pc, Rb2Pc, Cs2Pc) have been synthesized and purified to study their excited state behavior. Their UV-Vis electronic absorption spectra, fluorescence emission and excitation spectra, fluorescence quantum yields and lifetimes, as well as singlet oxygen formation quantum yields have been measured in DMF. These photophys. properties are compared with that of H2Pc. The fluorescence and singlet oxygen formation properties reveal that alk. metal Pcs show weak heavy atom effect. The results also reveal that alk.-metal Pcs (Na2Pc, K2Pc, Rb2Pc, and Cs2Pc) show very different excited singlet state (S1) behavior from that of Li2PC and H2Pc. While S1 decay of Li2PC is mainly via intersystem crossing and fluorescence, the S1 decay of M2Pc (M = Na, K, Rb, Cs) is mainly metal ion dissociation: M2Pc(S1) → 2 M+ + [Pc]2-(S1), in addition to the intersystem crossing.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about Excited singlet state. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Application of Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Feskov, Serguei V. published the artcileShort-Time Dynamics of Radical-Ion Pairs Produced by Photoinduced Electron Transfer in Solution: The Magnetic Field Effect, Category: nitriles-buliding-blocks, the main research area is dimethylanthracene phthalonitrile electron transfer magnetic field effect.

Kinetics of radical-ion pairs (RIPs) formed by photoinduced electron transfer in solution, as well as triplet and singlet products of their recombination, are studied within a general theory of spin-selective charge transfer assisted by diffusion of reactants in solution The RIPs are assumed to be created in the singlet state, and their coherent singlet-triplet evolution is described in terms of isotropic hyperfine interaction (HFI) and Δg mechanisms. A set of quantum-classical model equations is solved numerically using the time propagator splitting technique. Numerical simulations are carried out on a prototype photochem. reaction involving bimol. electron transfer between 9,10-dimethylanthracene (DMeA) and phthalonitrile (PN) in acetonitrile (ACN) solution Time-dependent populations of all electronic and spin states, as well as spatial distributions of reactants in the course of forward and backward charge transfer are calculated and analyzed. Particularly, spatial profiles of charge recombination (CR) in singlet and triplet RIPs are shown to differ significantly, with a significant part of the singlet RIPs undergoing distant (non-contact) recombination. The effect of a strong (saturating) magnetic field on the triplet CR product yield in these reactions is studied. For the HFI-induced coherent spin transitions, the time-dependent magnetic field effect is shown to decrease with time. A phenomenon of suppressing the triplet CR product yield in RIPs with the HFI- and Δg-induced coherent spin transitions in moderate magnetic fields is investigated and its phys. origins are discussed.

Applied Magnetic Resonance published new progress about Excited singlet state. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Category: nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kuznetsova, Aleksandra S. published the artcileMicrowave-assisted synthesis and sublimation enthalpies of hemiporphyrazines, HPLC of Formula: 91-15-6, the main research area is hemiporphyrazine preparation microwave irradiation.

It was established that microwave irradiation solvent-free processing of 2,6-diaminopyridine or 1,3-phenylenediamine with phthalonitrile or 4-tert-butylphthalonitrile led to corresponding hemiporphyrazines I (X = N, CH; Y = H, t-Bu; X = CH, Y = t-Bu, Z = H; X = CH, Y = H, Z = t-Bu) with sufficiently high yields and a huge reduction in the time required for synthesis, from 8-12 h to 20 min. The Knudsen effusion method with mass spectrometric control of vapor composition was applied. The mass spectrometric investigations established that the macrocyclic compounds I give a stable stream of particles and their enthalpies of sublimation were estimated by the second law of thermodn.

Journal of Porphyrins and Phthalocyanines published new progress about Microwave irradiation. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, HPLC of Formula: 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Zheng, Bing-De published the artcileA non-aggregated zinc(II) phthalocyanine with hexadeca cations for antitumor and antibacterial photodynamic therapies, Application of Phthalonitrile, the main research area is nonaggregated zinc phthalocyanine hexadeca cation antitumor antibacterial photodynamic therapy; Antibacterial; Anticancer; Cationic zinc(II) phthalocyanine; Non-aggregation; Photodynamic therapy.

With a view to developing highly efficient photosensitizers for both antitumor and antimicrobial photodynamic therapies, herein, we reported a super cationic zinc(II) phthalocyanine (Pc4), which was prepared through the quaternization of the N, N-dimethyl-3-aminophenoxyl-hexadeca-substituted precursor Pc3. Meanwhile, two disubstituted analogs (Pc1 and Pc2) were also prepared as controls. The cationic Pc2 and Pc4 had higher photoactivities including fluorescence and singlet oxygen than the neutral counterparts Pc1 and Pc3, probably because of the inhibition of intramol. charge transfer (ICT) effect of the amino groups. With the bulky steric effect and high hydrophilicity, Pc4 presented non-aggregated behavior in aqueous solutions Therefore, it exhibited the highest in vitro photodynamic activity toward HepG2 cancer cells with an IC50 value as low as 0.04 μM. Furthermore, Pc4 showed a highly efficient in vivo PDT effect on H22 tumor-bearing mice with 98.7% tumor growth inhibition. In addition, Pc4 also exhibited an excellent in vitro and in vivo photodynamic inactivation against S. aureus. The results indicate that the non-aggregated hexadeca-cationic Pc4 could serve as a promising photosensitizer for both antitumor and antimicrobial photodynamic therapies.

Journal of Photochemistry and Photobiology, B: Biology published new progress about Antibacterial agents. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Application of Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Wang, Xinying published the artcileDoxorubicin and Zinc phthalocyanine loaded pH-responsive FA-BSP-SA/TPGS micelles for synergistic chemo-photodynamic therapy against tumors, Product Details of C8H4N2, the main research area is zinc phthalocyanine folate Bletilla striata polysaccharide stearic acid micelle; micelle TPGS doxorubicin synergistic chemophotodynamic therapy tumor.

The present study was to evaluate the chemo-photodynamic synergistic antitumor effect of FA-BSP-SA/TPGS micelles loaded with doxorubicin (Dox) and Zinc phthalocyanine (ZnPc). Multiple evaluation parameters involving quality index (particle size, zeta potential, loading capacity, and encapsulation efficiency, etc), biocompatibility, in vitro drug release, and in vitro antitumor assays were performed to explore the optimal mass ratio in FA-BSP-SA/TPGS mixed micelles. The results showed that FA-BSP-SA/TPGS25 micelles were more ideal carriers. The synergistic antitumor effect of Dox and ZnPc was also investigated and proved to be better. Moreover, the current study revealed that TPGS, Dox, and ZnPc decreased mitochondrial membrane potential and increased ROS level in breast 4T1 cancer cells. Meanwhile, in vivo antitumor assay certified that Dox@FA-BSP-SA/TPGS25+ ZnPc@FA-BSP-SA/TPGS25 micelles showed the most superior antitumor effect. In conclusion, Dox@FA-BSP-SA/TPGS25+ZnPc@FA-BSP-SA/TPGS25 micelles are promising drug-loaded nanomaterials with synergistic chemo-photodynamic effects against cancer.

Journal of Drug Delivery Science and Technology published new progress about Agitation (mechanical). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Product Details of C8H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Ribeiro, Viviane G. P. published the artcileNanomaterials based on Fe3O4 and phthalocyanines derived from cashew nut shell liquid, Quality Control of 91-15-6, the main research area is iron oxide phthalocyanine Anacardium shell liquid nanomaterial; cashew nut shell liquid (CNSL); nanomaterials; phthalocyanines; superparamagnetic.

In this work we report the synthesis of new hybrid nanomaterials in the core/shell/shell morphol., consisting of a magnetite core (Fe3O4) and two consecutive layers of oleic acid (OA) and phthalocyanine mols., the latter derived from cashew nut shell liquid (CNSL). The synthesis of Fe3O4 nanoparticle was performed via co-precipitation procedure, followed by the nanoparticle coating with OA by hydrothermal method. The phthalocyanines anchorage on the Fe3O4/OA core/shell nanomaterial was performed by facile and effective sonication method. The as obtained Fe3O4/OA/phthalocyanine hybrids were investigated by Fourier transform IR spectroscopy, X-ray diffraction, UV-visible spectroscopy, transmission electron microscopy (TEM), thermogravimetric anal. and magnetic measurements. TEM showed round-shaped nanomaterials with sizes in the range of 12-15 nm. Nanomaterials presented saturation magnetization (Ms) in the 1-16 emu/g and superparamagnetic behavior. Furthermore, it was observed that the thermal stability of the samples was directly affected by the insertion of different transition metals in the ring cavity of the phthalocyanine mol.

Molecules published new progress about Anacardium occidentale. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Quality Control of 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Zhou, Tao published the artcileStudy on pyrolysis behaviors of L-tyrosine-based phthalonitrile resin, Synthetic Route of 91-15-6, the main research area is preparation tyrosine based phthalonitrile resin pyrolysis behavior property.

The pyrolysis behaviors of L-tyrosine-based phthalonitrile(TPN) resin were investigated by thermogravimetric-Fourier transform IR spectrometry-mass spectrometry and pyrolysis-gas chromatog./mass spectrometry. The small mols. produced during pyrolysis process of TPN resin were tracked in real time by TG-FTIR-MS. The larger mols. (m/z > 40) from fast pyrolysis at 900°C of the TPN resin using Py-GC/MS were identified. From TG-FTIR-MS and Py-GC/MS results, the production pathways of pyrolysis products such as CO2, CO, NH3, benzonitrile and phenol were analyzed. The possible pyrolysis mechanism of TPN resin under non-oxidizing gaseous environment was proposed. The results of this study provide the useful information for designing the mol. structure of L-tyrosine-based polymers which possessing high thermal stability.

Polymer Testing published new progress about Complex modulus, tan δ. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Synthetic Route of 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Yeganeh, Ardeshir Dadgar published the artcileIn situ synthesis and encapsulation of copper phthalocyanine into MIL-101(Cr) and MIL-100(Fe) pores and investigation of their catalytic performance in the epoxidation of styrene, Synthetic Route of 91-15-6, the main research area is copper phthalocyanine encapsulated MOF catalyst styrene epoxidation textural property.

In this work, copper phthalocyanine (CuPc) was encapsulated into mesocages of MIL-101(Cr) and MIL-100(Fe) by assembling CuPc’s constitutional fractions using a deep eutectic solvent. The prepared materials, CuPc@MIL-101(Cr) and CuPc@MIL-100(Fe), were characterized by powder X-ray diffraction (PXRD), FT-IR, UV-vis and diffuse reflectance UV (DR-UV) spectroscopies, SEM (SEM), transmission electron microscopy (TEM), and ICP-OES spectrometry. The prepared materials were used as heterogeneous catalysts for catalytic epoxidation of styrene with mol. oxygen and also tert-Bu hydroperoxide (TBHP) as oxidants in acetonitrile as a solvent. The impact of MOFs and the role of the CuPc complex as the active species in the MOFs’ cages in the epoxidation of styrene were investigated. Among the prepared catalysts, CuPc@MIL-101(Cr) showed the best performance. The heterogeneity of the catalysts was examined by a hot filtration test and ICP-OES of the filtrates after the reaction. Spent catalysts were analyzed by PXRD, FT-IR, UV-DRS, and TEM for reusability investigation and also to further explore the heterogeneous nature of the hybrid materials. Results showed that the prepared catalysts could be recycled and used for several concoctive times without a considerable drop in activity.

Journal of Porphyrins and Phthalocyanines published new progress about Deep eutectic solvents. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Synthetic Route of 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts