Category: 91-15-6

Ishizaki, Toshiharu published the artcileSynthesis of a Neutral Mononuclear Four-Coordinate Co(II) Complex Having Two Halved Phthalocyanine Ligands That Shows Slow Magnetic Relaxations under Zero Static Magnetic Field, SDS of cas: 91-15-6, the main research area is pseudotetrahedral four coordinate mononuclear Cobalt complex.

Syntheses of a novel pseudotetrahedral four-coordinate mononuclear Co(II) complex that has two halved phthalocyanine moieties as the ligands, [Co(half-Pc)2] (1), and its magnetic properties as a single mol. magnet (SMM) are reported. A one pot reaction of phthalonitrile and lithium methoxide followed by the coordination to a Co(II) ion gave 1 as an orange solid in a moderate yield. X-ray crystallog. on 1 reveals tetragonally distorted coordination geometry around the Co(II) ion. The M-HT-1 plots suggest that 1 has large axial magnetic anisotropy. The ac magnetic susceptibility data of the magnetically diluted 1 (dilute1) clearly show that the complex acts as an SMM even in the absence of the external static magnetic field (Hdc). The influence of intermol. and intramol. interactions for the magnetic relaxation behaviors has been discussed by comparison of the magnetic data of 1 and dilute1. The Orbach process is suggested as the predominant mechanism of magnetic relaxations in the high-temperature range, and the Arrhenius plots provide the effective relaxation energy barrier and pre-exponential factor of Ueff = 54.0 cm-1 and τ0 = 3.17 × 10-10 s, resp. The direct estimation of the axial anisotropic parameter of 1 was successfully performed by high-field, multifrequency ESR measurements up to 55 T and 2.5 THz. The evaluated axial zero-field splitting (ZFS) energy of 57.0 cm-1 is comparable to the Ueff energy, confirming that the magnetic relaxations are initiated by the thermal excitation from the ground |MS〉 = |±3/2〉 states to the |±1/2〉 states in the high-temperature range. The results of the ab initio calculations based on the CAS(7,5) SCF wave functions indicate that the ground states of 1 consist mainly of |MS〉 = |±3/2〉 states, while the first excited states are the mixture of |MS〉 = |+1/2〉 and |-1/2〉.

Inorganic Chemistry published new progress about Ground state, magnetic. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, SDS of cas: 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Yuan, Gankun published the artcileNovel Targeted Photosensitizer as an Immunomodulator for Highly Efficient Therapy of T-Cell Acute Lymphoblastic Leukemia, Computed Properties of 91-15-6, the main research area is dasatinib zinc phthalocyanine PDT photosensitizer preparation acute lymphoblastic leukemia.

Dasatinib is a kinase-targeted drug used in the treatment of leukemia. Regrettably, it remains far from optimal medicine due to insurmountable drug resistance and side effects. Photodynamic therapy (PDT) has proven that it can induce systemic immune responses. However, conventional photosensitizers as immunomodulators produce anticancer immunities, which are inadequate to eliminate residual cancer cells. Herein, a novel compound 4 was synthesized and investigated, which introduces dasatinib and zinc(II) phthalocyanine as the targeting and photodynamic moiety, resp. Compound 4 exhibits a high affinity to CCRF-CEM cells/tumor tissues, which overexpress lymphocyte-specific protein tyrosine kinase (LCK), and preferential elimination from the body. Meanwhile, compound 4 shows excellent photocytotoxicity and tumor regression. Significantly, compound 4-induced PDT can obviously enhance immune responses, resulting in the production of more immune cells. We believe that the proposed manner is a potential strategy for the treatment of T-cell acute lymphoblastic leukemia.

Journal of Medicinal Chemistry published new progress about Acute T-cell leukemia. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Computed Properties of 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Moradi, Parisa published the artcileMagnetization of biochar nanoparticles as a novel support for fabrication of organo nickel as a selective, reusable and magnetic nanocatalyst in organic reactions, Recommanded Product: Phthalonitrile, the main research area is organo nickel magnetic nanocatalyst biochar nanoparticle magnetization organic reaction.

Catalyst species are an important class of materials in chem., industry, medicine and biotechnol. Also, waste recycling is an important process in green chem. and economic efficiency. Therefore, in order to recycle waste, biochar nanoparticles were prepared from chicken manure. Then, the biochar nanoparticles were magnetized under a green and environmentally friendly method. Finally, the surface of the magnetic biochar nanoparticles was modified and further they were applied as a novel support for fabrication of nickel as a homoselective and reusable catalyst in organic reactions. The structure of this organic-inorganic catalyst has been characterized by N2 adsorption-desorption isotherms, and the SEM, EDS, WDX, XRD, TGA, AAS, FT-IR and VSM techniques. This magnetically recyclable catalyst was used in the homoselective synthesis of tetrazole and pyranopyrazole derivatives This catalyst can be reused several times without significant loss of its catalytic efficiency. The heterogeneity and stability of this nanocatalyst were studied by hot filtration and the AAS technique. Also, the reused catalyst was characterized by the SEM, EDS, AAS and BET techniques.

New Journal of Chemistry published new progress about Anti-inflammatory agents. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Recommanded Product: Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Dolensky, Bohumil published the artcileMethodology of deconvolution of total solute retention on chemically modified stationary phases to structure specific contributions of bound compounds, Application of Phthalonitrile, the main research area is methodol deconvolution retention modified stationary phase structure bound compound; binding constant; bound receptor; retention factor; retention mechanism; tweezer effect; weak affinity chromatography.

The total solute retention by a chem. modified stationary phase (CMSP) has been shown several times to be a potential tool for studying the binding abilities of the bound compound In this article, we present a methodol. for the deconvolution of the total retention into structure-specific contributions. Three complementary silica-based CMSPs were prepared: (1) non-modified silica,(2) silica modified by syn-bis-Troger’s base (a mol. tweezer) and (3) silica modified by anti-bis-Troger’s base (a non-tweezer mol.). These were characterized by elemental anal. and Raman spectroscopy, and used to assemble liquid chromatog. (LC) columns. The total retention factors were estimated for electron-deficient nitro- and cyano-derivatives of benzene in both normal and reverse elution modes. The total retention factor was considered to be the sum of structure-specific retention factors, each related to the affinity (the binding constant) of a specific structure (the binding site), and its content in the modified silica, as defined for weak-affinity chromatog. (WAC). The obtained structure-specific contributions are in line with the binding studies of ligands in solution They reveal details of the retention mechanism, suggesting a more suitable attachment of ligands, and expose the shortcomings of evaluations based solely on the total retentions.

Journal of Chromatography A published new progress about Affinity chromatography. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Application of Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Chanmungkalakul, Supphachok published the artcileA Descriptor for Accurate Predictions of Host Molecules Enabling Ultralong Room-Temperature Phosphorescence in Guest Emitters, Recommanded Product: Phthalonitrile, the main research area is guest emitter host mol room temperature phosphorescence; Afterglow Emission; Charge-Transfer State; Excited States; Intersystem Crossing; Room-Temperature Phosphorescence.

Although doping can induce room-temperature phosphorescence (RTP) in heavy-atom free organic systems, it is often challenging to match the host and guest components to achieve efficient intersystem crossing for activating RTP. In this work, we developed a simple descriptor ΔE to predict host mols. for matching the guest RTP emitters, based on the intersystem crossing via higher excited states (ISCHES) mechanism. This descriptor successfully predicted five com. available host components to pair with naphthalimide (NA) and naphtho[2,3-c]furan-1,3-dione (2,3-NA) emitters with a high accuracy of 83%. The yielded pairs exhibited bright yellow and green RTP with the quantum efficiency up to 0.4 and lifetime up to 1.67 s, resp. Using these RTP pairs, we successfully achieved multi-layer message encryption. The ΔE descriptor could provide an efficient way for developing doping-induced RTP materials.

Angewandte Chemie, International Edition published new progress about Energy level excitation. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Recommanded Product: Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Bhuse, Darpan Vijaykumar published the artcileVisible-Light Aided C-H activation: Metal/Base-Free Generation of C-C bonds using Porphyrin Photocatalyst, Category: nitriles-buliding-blocks, the main research area is porphyrin photocatalyst preparation green photochem arylation.

Herein, we report the application of a meso-substituted porphyrin dyad entangled with carboxyl functionalized benzimidazolium moieties (CPDCFBM) as a heterogeneous photocatalyst for C-H activation of various electron-donating and withdrawing aromatic compounds with highly inactivated aryl fluoride, chlorides, and other aryl bromides. A simple methodol. adopted to synthesize the corresponding product has received an outstanding yield from (69-88 %) under 5 W illumination using a homemade photoreactor assembly. CPDCFBM tolerated various functional groups with recyclability up to five runs without much decline in photocatalytic activity. Photogenerated excitons vitality in the reaction was analyzed using K2S2O8 and KI. CPDCFBM was shown a Hammett acidity value of 0.77. The reaction conditions were optimized as; time (18 h), catalyst (15 mg), and light illumination (5 W) from an LED source using ethanol as an eco-friendly solvent. The products obtained were crystalline and therefore need no further purification The electroanal. study revealed HOMO and LUMO energy of -5.841 and -4.066 resp. accounting for an energy gap of, 1.7 eV.

ChemistrySelect published new progress about Acidity function, Hammett. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Category: nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Deshmukh, Shubham Avinash published the artcileMetal Free Porphyrin Photocatalyst Comprising Ionic Liquid with Electron Donor Acceptor Moiety for Visible Light Assisted Oxidative Amination, Formula: C8H4N2, the main research area is porphyrin photocatalyst ionic liquid electron visible light oxidative amination.

Metal leaching and stability of heterogeneous catalysts is the main concern in pharmaceutical, fine chem. industries, enhancing metal contamination of the product. In this protocol, we report design and characterizations of a metal free porphyrin (MFPc) photocatalyst with electron donor acceptor (dicyano) moiety, for oxidative amination of benzyl amine under irradiation of 5 W LED light in a home-made photoreactor. Contrasted with the poor photocatalytic property of different derivatives of porphyrins, MFPc presents a significant improvement in imine formation (83%). The influence of various factors including quantity of catalyst, duration, and intensity of light (512 W), for oxidative amination were explored. MFPc with favorable properties like Hammett acidity (1.11), band gap (1.37 eV), explored for the synthesis of pharmaceutically important benzimidazole, from o-phenylene diamine. Moreover, MFPc displayed good reusability for 6 consecutive runs with negligible decrease in yield of imine at ambient reaction conditions. Addnl., a probable mechanism for imine formation was proposed.

ChemistrySelect published new progress about Acidity function, Hammett. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Formula: C8H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Schneider, Christian published the artcileRetrofitting metal-organic frameworks, Related Products of nitriles-buliding-blocks, the main research area is computational retrofitting metal organic framework density functional theory.

The post-synthetic installation of linker mols. between open-metal sites (OMSs) and undercoordinated metal-nodes in a metal-organic framework (MOF) – retrofitting – has recently been discovered as a powerful tool to manipulate macroscopic properties such as the mech. robustness and the thermal expansion behavior. So far, the choice of cross linkers (CLs) that are used in retrofitting experiments is based on qual. considerations. Here, we present a low-cost computational framework that provides experimentalists with a tool for evaluating various CLs for retrofitting a given MOF system with OMSs. After applying our approach to the prototypical system CL@Cu3BTC2 (BTC = 1,3,5-benzentricarboxylate) the methodol. was expanded to NOTT-100 and NOTT-101 MOFs, identifying several promising CLs for future CL@NOTT-100 and CL@NOTT-101 retrofitting experiments The developed model is easily adaptable to other MOFs with OMSs and is set-up to be used by experimentalists, providing a guideline for the synthesis of new retrofitted MOFs with modified physicochem. properties.

Nature Communications published new progress about Density functional theory. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Related Products of nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Thimiopoulos, A. published the artcileAsymmetric phthalocyanines (A3B type) containing aminophenoxy and hydroxyphenyl-diazenyl-phenoxy substituents, Recommanded Product: Phthalonitrile, the main research area is transition metal phthalocyanine complex preparation fluorescence electrochem; DFT mol structure transition metal phthalocyanine complex.

In this research new asym. metal-phthalocyanine complexes (A3B-type), with Zn2+, Co2+ and Ru2+, bearing aminophenoxy and hydroxyphenyl-diazenyl-phenoxy substituents, were synthesized. The synthetic route to asym. Pcs (A3B-type), based on ring expansion method is refined. The photophys. and electrochem. properties of the new phthalocyanines were investigated. In addition to this investigation, a comparative study took place on the effect of the expansion of conjunction on properties of the MPc compound Also, the effect of pH to the ground state electronic absorption spectra of compounds bearing hydroxyphenyl-diazenyl-phenoxy substituents was also studied. Theor. studies (DFT) were also carried out to support the corresponding exptl. results.

Inorganica Chimica Acta published new progress about Electrochemical oxidation. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Recommanded Product: Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Flores, Soraya Y. published the artcileFluorinated Iron and Cobalt Phthalocyanine Nanowire Chemiresistors for Environmental Gas Monitoring at Parts-per-Billion Levels, Application of Phthalonitrile, the main research area is fluorinated iron cobalt phthalocyanine nanowire gas sensor environmental monitoring.

Herein, a single-step production for the development of gas sensing devices from unsubstituted and hexadecafluorinated metal phthalocyanines (MPc, M = Fe2+ and Co2+) is explained. The preparation of sensor devices by the direct growth of nanowires on interdigitated electrodes by the vapor transport of the synthesized MPc precursors is discussed, emphasizing a single-step approach. Results using as-prepared devices for the detection of NH3 and NO2 in the ppb range are shown. In agreement with similar MPc sensing materials, response and recovery times fitted using a double-exponential model gave two rate constants: a short one, on the order of minutes for concentrations above 500 ppb, and a long one, on the order of hours. These rate constants are suitable for environmental monitoring of gases in recovery zones, where longer exposure times are critical in the sampling process. Our F16FePc-NW sensor prototypes show a ~10% normalized response toward NH3 at 40 ppb for a measuring time of ~2.5 h at room temperature and measurable responses to concentrations as low as 5 ppb, rendering them applicable to environmental studies.

ACS Applied Nano Materials published new progress about Air pollution monitoring. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Application of Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts