Category: 91-15-6

Ma, Yueyue published the artcileDirect Arylation of α-Amino C(sp3)-H Bonds by Convergent Paired Electrolysis, Category: nitriles-buliding-blocks, the main research area is tertiary amine benzonitrile TEMPO catalyst electrochem arylation; benzylic amine preparation regioselective; C−H activation; arylation; cross-coupling; electrocatalysis; tertiary amines.

A metal-free convergent paired electrolysis strategy to synthesize benzylic amines through direct arylation of tertiary amines and benzonitrile derivatives at room temperature was developed. This TEMPO-mediated electrocatalytic reaction made full use of both anodic oxidation and cathodic reduction without metals or stoichiometric oxidants, thus showing great potential and advantages for practical synthesis. This convergent paired electrolysis method provided a straightforward and powerful means to activate C-H bonds and realize cross-coupling with cathodically generated species.

Angewandte Chemie, International Edition published new progress about Aralkyl amines Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Category: nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nasrollahzadeh, Mahmoud published the artcilePd nanocatalyst adorning coral reef nanocomposite for the synthesis of nitriles: utility of Cucurbita pepo leaf extract as a stabilizing and reducing agent, Application In Synthesis of 91-15-6, the main research area is palladium nanocatalyst coralreef nanocomposite nitrile Cucurbita stabilizing reducing agent; Cucurbita pepo; Pd nanoparticles; Pd/coral reef nanocomposite; aryl halide; cyanation.

A simple procedure for the palladium-catalyzed cyanation of aryl halides is described via a nucleophilic non-toxic cyanide source, K4[Fe(CN)6] in the presence of Pd/coral reef nanocomposite as a heterogeneous catalyst; the protocol provides a useful and easy method for the synthesis of aryl nitriles that are generated from the corresponding variant aryl halides, with sodium carbonate as a base. The nanocatalyst was prepared by a biol. process using aqueous extract of leaves of Cucurbita pepo as a stabilizing and reducing agent and coral reef as a natural support, without deploying any hazardous chems. The catalyst, that is easily separable from the reaction mixture and reused multiple times, was characterized by FT-IR (Fourier-Transform IR Spectroscopy), ICP-AES (Inductively Coupled Plasma Atomic Emission Spectroscopy), XRD (X-ray Diffraction), TEM (Transmission Electron Microscopy), FE-SEM (Field Emission SEM), EDS (Energy Dispersive X-ray Spectroscopy) and elemental mapping.

Nanomaterials published new progress about Aromatic nitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Application In Synthesis of 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Wang, Shengyu published the artcilePd@CeO2-catalyzed cyanation of aryl iodides with K4Fe(CN)6·3H2O under visible light irradiation, Category: nitriles-buliding-blocks, the main research area is aryl nitrile preparation green chem photochem; potassium ferricyanide aryl iodide cyanation palladium catalyst.

A new protocol based on the combination of the catalyst Pd@CeO2, nontoxic cyanide source K4Fe(CN)6·3H2O, and driving force visible light irradn was developed. The reaction is performed at relatively moderate temperature (55°C) and exhibits good catalytic efficiency of product aryl nitriles RCN (R = Ph, 2-nitrophenyl, thiophen-2-yl, etc.) (yields of 89.4%). Moreover, the catalyst Pd@CeO2 possesses good reusability with a slight loss of photocatalytic activity after five consecutive runs. The reaction system based on the above combination shows a wide range of functional group tolerance under the same conditions. Reaction conditions such as temperature, time, the component of catalyst, and solutions are optimized by studying cyanation of 1-iodo-4-nitrobenzene as model reaction. According to these results, the possible mechanism of Pd@CeO2-catalyzed cyanation of aryl iodides RI under visible light irradiation is proposed based on the influence of visible light on the catalyst and reactant compounds In all, an environmental and economic method for preparation of aryl nitriles from cyanation of aryl iodides based on the goal of green chem. for sustainable development was provided.

Applied Organometallic Chemistry published new progress about Aromatic nitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Category: nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Heydari, Somayyeh published the artcileAn overview on the progress and development on the palladium catalyzed direct cyanation, SDS of cas: 91-15-6, the main research area is aryl nitrile preparation; arylsulfonyl cyanamide phenylboronic acid cyanation palladium catalyst.

The simultaneous use of the new Pd nano-catalyst as well as the three types of the N-arylsulfonyl cyanamides 4-ClC6H4N(CN)S(O)2C6H4(4-X) (X = CH3, Br, NO2) as potent reagents for the in situ generation of the pos. CN ion for the direct cyanation of phenylboronic acids ArB(OH)2 [Ar = 4-ClC6H4, pyridin-3-yl, 2-(dihydroxyboranyl)phenyl, etc.] in acetonitrile at reflux conditions has been described.

Inorganica Chimica Acta published new progress about Aromatic nitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, SDS of cas: 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Tavakoli, Ghazal published the artcileThe reductive deaminative conversion of nitriles to alcohols using para-formaldehyde in aqueous solution, COA of Formula: C8H4N2, the main research area is benzylic alkyl primary alc chemoselective preparation; ruthenium catalyst chemoselective reduction nitrile paraformaldehyde water; mechanism reductive deamination nitrile paraformaldehyde water ruthenium catalyst.

In the presence of [Ru(p-cymene)Cl2]2, paraformaldehyde in H2O/toluene acted as a reductant for the chemoselective reductive deamination of alkyl and aryl nitriles to yield alkyl or benzylic primary alcs. The mechanism of the reaction is studied using the characterization of reaction intermediates by mass spectrometry; dimeric ruthenium complexes are necessary to generate reduced ruthenium complexes from paraformaldehyde, while nitrile coordination generates monomeric complexes of ruthenium which reduce the nitriles to alcs.

Catalysis Science & Technology published new progress about Aralkyl alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, COA of Formula: C8H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Chen, Huan published the artcileBurn Intensity Drives the Alteration of Phenolic Lignin to (Poly) Aromatic Hydrocarbons as Revealed by Pyrolysis Gas Chromatography-Mass Spectrometry (Py-GC/MS), Synthetic Route of 91-15-6, the main research area is phenolic lignin polyaromatic hydrocarbon PyGC MS; alkyl side chain; black carbon/nitrogen; forest fuel reduction; prescribed fire; wildfire.

High-intensity wildfires alter the chem. composition of organic matter, which is expected to be distinctly different from low-intensity prescribed fires. Herein, we used pyrolysis gas chromatog./mass spectrometry (Py-GC/MS), in conjunction with solid-state 13C NMR and Fourier transform IR (FT-IR) spectroscopy, to assess chem. alterations from three wildfires and a long-term frequent prescribed fire site. Our results showed that black ash formed under moderate intensity burns contained less aromatic (ArH), polyaromatic hydrocarbon (PAH), and nitrogen-containing compounds (Ntg) but more lignin (LgC) and phenol compounds (PhC), compared to white ash formed under high intensity burns. Both 13C NMR and FT-IR confirmed a higher relative percentage of carboxyl carbon in white ash, indicating the potential for higher water solubility and more mobile carbon, relative to black ash. Compared to wildfires, ash from low-intensity prescribed fire contained less ArH, PAH, and Ntg and more LgC and PhC. Controlled laboratory burning trials indicated that organic matter alteration was sensitive to the burn temperature, but not related to the fuel type (pine vs. fir) nor oxygen absence/presence at high burn temperatures This study concludes that higher burn temperatures resulted in higher (poly)aromatic carbon/nitrogen and lower lignin/phenol compounds

Environmental Science & Technology published new progress about Aromatic hydrocarbons Role: NUU (Other Use, Unclassified), USES (Uses). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Synthetic Route of 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Watanabe, Koh published the artcileReductive Cross-Coupling between Arylaldehydes and (Hetero)aryl Electrophiles Using Silylboronate Reductant, HPLC of Formula: 91-15-6, the main research area is diarylmethanol preparation; arylaldehyde heteroaryl electrophile cross coupling reaction.

A catalytic reductive cross-coupling between arylaldehydes ArCHO (Ar = Ph, 2-methylphenyl, naphthalen-2-yl, thiophen-2-yl, etc.) and aryl electrophiles RX (R = pyridin-2-yl, 3-methylpyridin-2-yl, 1,3-benzothiazol-2-yl, etc.; X = F, Cl, CN) using a silylboronate Si(Et)3(B)C(Me)2C(Me)2 as a terminal reductant is described. The reaction involves a copper-catalyzed silylboration of aldehydes affording the O-borylated α-silyl alcs. ArCH(R)OSi(Et)3 (I) followed by a nucleophilic aromatic substitution reaction with aryl electrophiles. This protocol offers a new opportunity to access 1,1-diarylmethanol derivatives (I) without rare metals or highly basic organometallic reagents.

European Journal of Organic Chemistry published new progress about Alcohols, silyl Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, HPLC of Formula: 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Liu, Yuliang published the artcilePhotoinduced Cross-Coupling of Aryl Iodides with Alkenes, Recommanded Product: Phthalonitrile, the main research area is aryl iodide alkene photoinduced cross coupling UV absorption.

A protocol for photoinduced cross-coupling of aryl iodides having polar π-functional groups or elongated π-conjugation with alkenes was developed. The radical cascade mechanism involving generation of aryl radicals via C-I bond homolysis of photoexcited aryl iodides and their subsequent addition to alkenes was proposed. The method enabled iodide-selective cross-coupling over other halogen leaving groups with functional group compatibility on both arene and alkene motifs.

Organic Letters published new progress about Aralkyl ketones Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Recommanded Product: Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Shee, Maniklal published the artcileOrganophotoredox assisted cyanation of bromoarenes via silyl-radical-mediated bromine abstraction, Quality Control of 91-15-6, the main research area is organophotoredox catalyzed cyanation bromoarene silyl radical bromine abstraction.

The insertion of a nitrile (-CN) group into arenes through the direct functionalization of the C(sp2)-Br bond is a challenging reaction. Herein, we report an organophotoredox method for the cyanation of aryl bromides using the organic photoredox catalyst 4CzIPN (1,2,3,5-tetrakis(carbazol-9-yl)-4,6-dicyanobenzene) and tosyl cyanide (TsCN) as the nitrile source. A photogenerated silyl radical, via a single electron transfer (SET) mechanism, was employed to abstract bromine from aryl bromide to provide an aryl radical, which was concomitantly intercepted by TsCN to afford the aromatic nitrile. A range of substrates containing electron-donating and -withdrawing groups was demonstrated to undergo cyanation at room temperature in good yields. Thus, e.g., Me 4-bromobenzoate �Me 4-cyanobenzoate (71%) employing 4CzIPN, TsCN, (TMS)3SiOH as silyl radical source, K3PO4 as base, acetone as solvent and irradiation from blue LED.

Chemical Communications (Cambridge, United Kingdom) published new progress about Aromatic nitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Quality Control of 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nasrollahzadeh, Mahmoud published the artcileSynthesis, characterization and catalytic performance of Pd(II) complex immobilized on Fe3O4@SiO2 nanoparticles for the ligand-free cyanation of aryl halides using K4Fe(CN)6, Recommanded Product: Phthalonitrile, the main research area is reusable iron oxide supported palladium nanocatalyst preparation surface area; potassium ferrocyanate aryl halide reusable palladium nanocatalyst cyanation; aryl nitrile preparation green chem.

The preparation of a novel magnetic catalyst via immobilization of Pd(II)-N-benzyl-N-(4-bromophenyl)-5-amino-1H-tetrazole complex on the Fe3O4@SiO2 nanoparticles (NPs). The application of Fe3O4@SiO2 NPs supported Pd(II)-N-benzyl-N-(4-bromophenyl)-5-amino-1H-tetrazole complex [Fe3O4@SiO2-BAT-Pd(II)] nanocatalyst was described for the cyanation of aryl iodides and bromides to the corresponding aryl nitriles using potassium hexacyanoferrate(II) [K4Fe(CN)6] as a non-toxic and economic cyanating agent under ligand- and additive-free conditions. Some aryl nitriles were efficiently synthesized from the corresponding aryl bromides and iodides in the presence of Fe3O4@SiO2-BAT-Pd(II) nanocomplex. The core-shell nanocomplex demonstrated the superior catalytic performance for the synthesis of synthetically valuable aryl nitriles within good to excellent yields. This process eliminated the need to handle highly toxic metal cyanides and it was easily recovered and reused for six consecutive runs with no decreasing of its catalytic capability. Preparation of Pd(II) complex immobilized on Fe3O4@SiO2 nanoparticles [Fe3O4@SiO2-BAT-Pd(II) nanocomplex]. Characterization of Fe3O4@SiO2-BAT-Pd(II) nanocomplex using XRD, FT-IR, EDS, VSM, TEM and FESEM analyses. Catalytic cyanation of the various aryl halides with K4Fe(CN)6 under ligand-free conditions. The nanocomplex was recovered and isolated six times with no significant loss of its catalytic ability.

Applied Organometallic Chemistry published new progress about Aromatic nitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Recommanded Product: Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts