Nitriles-buliding-blocks

Nitrile is any organic compound with a −C≡N functional group. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Synthetic Route of 31643-49-9.

Xia, Yunqing;Zhang, Shuai;Tong, Lifen;Liu, Shuning;Lin, Guo;Bai, Zhongxiang;He, Yi;Liu, Xiaobo research published 《 Introducing cyano-functionalized multiwalled carbon nanotubes to improve corrosion resistance and mechanical performance of poly(arylene ether nitrile) coating》, the research content is summarized as follows. Seeking high-performance coating with long service life to protect metallic substrates under complex corrosion environment has attracted abundant attention in modern industry. In this work, poly(arylene ether nitrile) (PEN) was applied as protective coating on metallic substrates for the first time, and the cyano-functionalized multiwalled carbon nanotubes (MWCNTs-CN) was introduced to further enhance the corrosion resistance and mech. performance of the PEN coating. Electrochem. results demonstrated that the MWCNTs-CN incorporated composite coating possessed outstanding corrosion resistance that the |Z|0.01Hz remained 196.9 MΩ cm2 after 100 days immersion process in 3.5 wt% NaCl solution, which was 2 orders of magnitude higher than the pure PEN coating. Besides, an evident improvement was investigated from the tensile strength of MWCNTs-CN/PEN coatings, which showed an increment about 20.1% of tensile strength was gained when 1 wt% of MWCNTs-CN was introduced. Benefiting from these advantages, this work is expected to provide a novel insight in high-performance protective coating.

Synthetic Route of 31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Name: Tetrafluoroterephthalonitrile.

Xia, Yu;Wang, Yan;Cao, Hongyan;Lin, Shuhao;Xia, Yongsheng;Hou, Xiaoxuan;Wu, Yulin;Yu, Ying;Huang, Kang;Xing, Weihong;Xu, Zhi research published 《 Rigidly and intrinsically microporous polymer reinforced sulfonated polyether ether ketone membrane for vanadium flow battery》, the research content is summarized as follows. Ion exchange membranes (IEMs) blending porous materials have shown great potential for the large-scale energy storage technologies, such as flow battery. However, it remains challenging to overcome the compatibility issue between polymer and porous fillers. In this work, the polymer of intrinsic microporosity (PIM) was successfully introduced into sulfonated polyether ether ketone with high degree of sulfonation (HDS-SPEEK) membrane. PIM exhibited desirable compatibility with HDS-SPEEK due to the natural polymer property. Meanwhile, the rigid skeleton structure of PIM effectively solved the problems of HDS-SPEEK involving poor mech. property and low vanadium resistance. With increasing the doping of carboxyl grafting modified PIM, the tensile strength increased from 15.22 to 29.94 MPa and the vanadium permeability declined from 4.4 x 10^-6 to 1.6 x 10^-7 cm² min^-1. As a result, the vanadium flow battery equipped with the optimized blend membrane showed significantly enhanced coulombic efficiency from 55% to 99% at the c.d. of 20 mA cm^-2, and had good long-term stability. This work presents a new route to prepare high-performance IEMs based on porous PIM materials for flow battery.

Name: Tetrafluoroterephthalonitrile, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , 1835-49-0.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Computed Properties of 31643-49-9.

Wu, Yanling;Wei, Chuangyu;Wang, Hongyuan;Mei, Zhuang;Xing, Qianli;Su, Jie;Ning, Zeyu;Chen, Yanli;Jiang, Jianzhuang research published 《 High-selective room-temperature NO₂ sensors based on a coumarin-substituted tris(phthalocyaninato) europium》, the research content is summarized as follows. A novel coumarin-substituted phthalocyaninato triple-decker complex, Eu₂[Pc(Cou)₄]₃ is designed and synthesized successfully. Introduction of the coumarin substituents onto the periphery of a phthalocyanine ring in the sandwich-type phthalocyaninato triple-decker not only increased the solubility and improved the film-forming ability, but also importantly ensured the suitable HOMO and LUMO energy levels. The solution-processed thin film of the Eu₂[Pc(Cou)₄]₃ was prepared by a simple and low-cost quasi-Langmuir-Shafer (QLS) method and applied as the gas sensor for the detection of NO₂. Importantly, within the dynamic exposure period of 1 min, balanced, stable, a reproducible n-type response to electron-accepting gas NO₂ in the range of 4-35 ppm, was revealed, based on the QLS film of Eu₂[Pc(Cou)₄]₃ complex at room temperature, dependant on the optimized mol. packing in J-aggregation mode with a large sp. surface area and good film conductivity

Computed Properties of 31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Safety of Tetrafluoroterephthalonitrile.

Wu, Yanan;Gui, Huiqiang;Ma, Liangwei;Zou, Lei;Ma, Xiang research published 《 Red-light emissive phosphorescent polymers based on X-shaped single benzene》, the research content is summarized as follows. Recently, the single benzene mol. has attracted widespread attention in room temperature phosphorescence (RTP) materials for its simple structure. However, it is difficult to achieve the long wavelength emission and there are few feasible, universal strategies to construct phosphors with long wavelength emission. In this study, a series of X-shaped phosphors derived from tetrafluoroterephthalonitrile were synthesized and copolymerized with acrylamide to obtain RTP materials. Polymers containing selenium (Se) atoms exhibited long wavelength RTP emission around 600 nm and over 200 nm Stokes shift. PN1, the fluorescence and phosphorescence dual emission material, exhibited red phosphorescence emission at 605 nm. Theor. calculation was performed to explain the underlying reasons for the produce of phosphorescence.

1835-49-0, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , Safety of Tetrafluoroterephthalonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Reference of 1835-49-0.

Wu, Pengfei;Zhou, Long;Xia, Shuwei;Yu, Liangmin research published 《 Synthesis of luminescent cocrystals based on fluoranthene and the analysis of weak interactions and photophysical properties》, the research content is summarized as follows. A series of luminescent cocrystals with fluoranthene (C16H10) as the fluorophore and benzene-1,2,4,5-tetracarbonitrile (TCNB, C10H2N4), 2,3,5,6-tetrafluorobenzene-1,4-dicarbonitrile (TFP, C8F4N2) and 1,2,3,4,5,6,7,8-octafluoronaphthalene (OFN, C10F8) as the coformers was designed and synthesized. Structure anal. revealed that these layered structures were due to charge transfer, π-π interactions and hydrogen bonding. D. functional theory (DFT) calculations show that fluoranthene-TCNB and fluoranthene-TFP have charge-transfer properties, while fluoranthene-OFN does not, indicating that fluoranthene-OFN has arene-perfluoroarene (AP) interactions, which was also demonstrated by spectroscopic anal., which shows that the photophys. properties of luminescent materials can be tuned by forming cocrystals. These results all prove that utilizing supramol. cocrystals to develop new fluorescent materials is an effective strategy, which has much potential in optoelectronic applications.

Reference of 1835-49-0, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , 1835-49-0.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Name: 4-Nitrophthalonitrile.

Wu, Minjie;Gu, Yuxuan;Hao, Diyi;Chen, Xinggang;Yu, Xiaoyan;Zhang, Qingxin research published 《 Fluorinated Phthalonitrile Resin with Excellent Thermal Stability and Low Dielectric Constant for High-Frequency Electronic Packaging》, the research content is summarized as follows. Phthalonitrile (PN) resin promising material for preparing high-speed and high-frequency electronic packaging because of its unique high temperature resistance and excellent insulation performance. A fluorinated PN oligomer (4,4′-bis (p-perfluoro-phenol-(bis(p-phenol)perfluoropropane-2,2-diyl)-p-oxy-diphthalonitrile) (PFDP)) containing trifluoromethyl and decafluorobiphenyl groups are designed, synthesized, and characterized. The oligomer is blended with 4-(aminophenoxy)phthalonitrile (APPH), and then cured into polymers under the temperature-programmed process. The reactive blend has good processability, and structures of isoindole, triazine ring, and phthalocyanine ring are found in the curing reactions. The fluorinated PN (P-380) shows outstanding thermal stability and mech. properties (5% thermal degradation temperature: 518°C (N₂); 516 (Air), T_{Heat-resistance index}: 268°C, activation energy of thermal decomposition: 334.89 kJ mol^-1, glass transition temperature (T_g) > 400°C). Meanwhile, the fluorinated PN simultaneously exhibited a superior low dielec. constant (D_k, 2.21) and dielec. loss (D_f, 0.01) at 10 GHz. Moreover, the water absorption of the resin is as low as 0.74%, which meets the requirement of dielec. materials. These results would strongly suggest such PFDP PN resin as excellent packaging materials in those high-tech applications such as aerospace and communication electronic devices.

31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., Name: 4-Nitrophthalonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion. COA of Formula: C8H3N3O2.

Wu, Mei;Huang, Sheng;Hou, Huiqing;Lin, Jie;Lin, Mei;Zhou, Sunying;Zheng, Zhiqiang;Sun, Weiming;Ke, Fang research published 《 DIPEA-induced activation of OH^– for the synthesis of amides via photocatalysis》, the research content is summarized as follows. Herein, an efficient light-mediated strategy for the synthesis of amides in which a weak organic base acts as a reductant to induce the formation of OH- from water under metal-free conditions was reported. A mechanistic study revealed that the generation of an N,N-diisopropylethylamine (DIPEA) radical via single electron transfer (SET), with the assistance of photocatalyst, that increased the nucleophilicity of the water mols. with respect to the cyanides was essential. Moreover, the removal rate of nitrile in wastewater can be as high as 83%, indicating that this strategy had excellent potential for nitrile degradation

COA of Formula: C8H3N3O2, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Product Details of C9H5N.

Wu, Jianglong;Wang, Chenyu;Wang, Zhongjie;Li, Hongjun;Liu, Ruyan;Wang, Yan;Zhou, Pengsheng;Li, Dianjun;Yang, Jinhui research published 《 Base/B₂pin₂-Mediated Iodofluoroalkylation of Alkynes and Alkenes》, the research content is summarized as follows. A base/B₂pin₂-mediated iodofluoroalkylation of alkynes and a part of alkenes, using Et difluoroiodoacetate (ICF₂CO₂Et) or IC_nF_2n+1(n = 3, 4, 6) as difluoroacetylating or perfluoroalkylating reagent, is disclosed. The reaction proceeds under mild conditions, and iododifluoroalkylation, hydrodifluoroalkylation and several perfluoroalkylation products were generated from alkynes or alkenes. Notably, this methodol. provides a simple access to difluoroalkylated and perfluoroalkylated organic compounds starting from simple alkynes or alkenes.

Product Details of C9H5N, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Quality Control of 105-34-0.

Wu, Feng;Du, Juan;Liu, Na;Xu, Jie;Xue, Bing research published 《 Potassium-doped carbon nitride supported on SBA-15 for enhanced catalytic Knoevenagel condensation under mild conditions》, the research content is summarized as follows. Knoevenagel condensation reaction is an important reaction for the manufacture of α,β-unsaturated carbonyl compounds Traditional base catalysts suffer from the disadvantage in catalyst-product separation Herein, potassium-doped carbon nitride materials supported on SBA-15 (CN/SBA15-KCl) have been prepared through a one-pot calcination method. The characterization results of N₂ adsorption-desorption, small-angle XRD, TEM, and SEM revealed that the ordered mesostructures of SBA-15 had been preserved after the loading of carbon nitride and KCl, and nitrogen and potassium species were dispersed on the surface of SBA-15 support. As solid bases, the CN/SBA15-KCl materials demonstrated high and steady catalytic performances in Knoevenagel condensation. Under 50°C of reaction temperature, the optimized conversion of benzaldehyde was up to 74% at 4 h of reaction time, much higher than other carbon-nitride-based materials. The incorporation of potassium has been proved to enhance the basic strength of CN/SBA15, and therefore improved the catalytic activity.

105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., Quality Control of 105-34-0

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Computed Properties of 20099-89-2.

Williams, Matthew B.;Boyer, Alistair research published 《 Modular Synthesis of Highly Substituted 3-Azapyrroles by Rh(II) Catalyzed N-H Bond Insertion and Cyclodehydration》, the research content is summarized as follows. A modular synthesis of highly substituted 3-azapyrroles, e.g., I has been developed using a three-step sequence comprising: copper catalyzed alkyne-azide cycloaddition (CuAAC), N-H bond insertion and cyclodehydration. The compound 1-sulfonyl-1,2,3-triazoles (1-STs), e.g., 4-tolyl-1-tosyl-triazole can be accessed from common alkynes, e.g., 4-ethynyltoluene and sulfonyl azides, e.g., 4-toluenesulfonyl azide building blocks by CuAAC using copper(I) thiophene-2-carboxylate. Rhodium(II) acetate promoted 1-ST denitrogenation results in highly electrophilic rhodium azavinyl carbenes that, here, underwent insertion into the N-H bond of secondary α-aminoketones, e.g., 1-(4-tolyl)-2-(4-tolylamino)ethan-1-one to form 1,2-aminoalkenes, e.g., 1-[(2-oxo-2-(4-tolyl)ethyl)(4-tolyl)amino]-1-(4-tolyl)-2-(tosylamino)ethene. These products were cyclized and dehydrated using BF₃OEt₂ into highly substituted 3-azapyrroles, e.g., I. The three steps: CuAAC, N-H bond insertion and cyclodehydration could be telescoped into a one-pot process. The method proved to be highly efficient and tolerated a wide range of substituents.

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., Computed Properties of 20099-89-2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts