Tag: 100-200

《Novel triazine-based cationic covalent organic polymers for highly efficient and selective removal of selenate from contaminated water》 was written by Lin, Wenxia; Wu, Pengcheng; Li, Rongfei; Li, Jihong; Cai, Yimin; Yuan, Lihua; Feng, Wen. HPLC of Formula: 17201-43-3This research focused ontriazine covalent organic framework selenate adsorption water purificaton; Adsorption; Contaminated water treatment; Covalent triazine framework; Selenium removal. The article conveys some information:

Selenium (Se) removal from contaminated water has become a major environmental problem in recent years. Designing efficient and selective materials for selenium adsorption is urgent and still represents a great challenge. Herein, two novel cationic covalent triazine frameworks (CTFS-Cl and CTFL-Cl) are developed for the first time and employed as a new class of Se adsorbents. The results from systematic adsorption experiments indicate that these materials can adsorb SeO2-4 in a wide range of pH values (2-11) with fast kinetics (5 min), outstanding adsorption capacity, and excellent selectivity over other competing anions. The maximum adsorption capacity achieved (149.3 mg/g by CTFS-Cl) constitutes one of the highest values among the organic polymeric materials. More importantly, after a single step adsorption, these materials can reduce the Se concentrations to lower than 10μg/L, the lowest drinking water standard in the world. The adsorption mechanism was probed by XPS technique, EDS anal., adsorption experiments, and DFT calculations, which reveals that anion exchange between Cl- and SeO2-4 is the main driving force for Se adsorption. Addnl., CTFS-Cl and CTFL-Cl perform well toward real contaminated river water sample with the residual Se being less than 8.49μg/L. This work demonstrates the excellent performance of CTFs-based materials with great application prospect for Se removal in contaminated water treatment. The results came from multiple reactions, including the reaction of 4-Cyanobenzyl bromide(cas: 17201-43-3HPLC of Formula: 17201-43-3)

4-Cyanobenzyl bromide(cas: 17201-43-3) can reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile. And it may be used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile.HPLC of Formula: 17201-43-3

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Nitrile – Wikipedia,
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Application In Synthesis of 2-BromobenzonitrileIn 2021 ,《Paired Electrolysis Enabled Ni-Catalyzed Unconventional Cascade Reductive Thiolation Using Sulfinates》 was published in Journal of Organic Chemistry. The article was written by Kang, Jun-Chen; Li, Zi-Hao; Chen, Chao; Dong, Li-Kun; Zhang, Shu-Yu. The article contains the following contents:

Herein, authors have reported a nickel-catalyzed cascade reductive thiolation of aryl halides with sulfinates driven by paired electrolysis. This protocol uses sulfinates as the sulfur source, and various thioethers could be synthesized under mild conditions. By mechanism exploration, authors find that a cascade chem. step is allowed on the electrode interface and could alter the reaction pathway in paired electrolysis, whose findings could help the discovery of novel cascade reactions with unique reactivity. In the part of experimental materials, we found many familiar compounds, such as 2-Bromobenzonitrile(cas: 2042-37-7Application In Synthesis of 2-Bromobenzonitrile)

2-Bromobenzonitrile(cas: 2042-37-7) belongs to a group of ortho-substituted bromobenzenes that have varying hepatotoxicity effects in the presence of rat liver microsomes in vitro. 2-Bromobenzonitrile is also used as a starting material to synthesize novel benzothiophene derivatives that were found to exhibit antibacterial and antifungal activity.Application In Synthesis of 2-Bromobenzonitrile

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Nitrile – Wikipedia,
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Quality Control of 2-BromobenzonitrileIn 2021 ,《Arylbiamidines: synthesis and structural studies en route to anticancer applications》 was published in New Journal of Chemistry. The article was written by Grytsai, Oleksandr; Goncalves, Leticia Christina Pires; Bardovskyi, Rostyslav; Hamouda-Tekaya, Nedra; Rocchi, Stephane; Ronco, Cyril; Benhida, Rachid. The article contains the following contents:

Biamidines are a unique and poorly studied class of nitrogenous compounds prone to tautomerization and H-bonding. Four series of heteroaryl diarylbiamidines were synthesized and the antimelanoma activity and physicochem. properties of the resulting 37 new compounds were evaluated. The dimethylthiazolyl 3-bromophenyl biamidine derivative B6 (I) inhibits the growth of six different melanoma cell lines, having higher activity than the pos. control drug, the B-RAF inhibitor PLX4032. This study introduces diarylbiamidines as promising frameworks for drug discovery. In addition to this study using 2-Bromobenzonitrile, there are many other studies that have used 2-Bromobenzonitrile(cas: 2042-37-7Quality Control of 2-Bromobenzonitrile) was used in this study.

2-Bromobenzonitrile(cas: 2042-37-7) belongs to a group of ortho-substituted bromobenzenes that have varying hepatotoxicity effects in the presence of rat liver microsomes in vitro. 2-Bromobenzonitrile is also used as a starting material to synthesize novel benzothiophene derivatives that were found to exhibit antibacterial and antifungal activity.Quality Control of 2-Bromobenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Related Products of 31938-07-5In 2021 ,《Silver/manganese dioxide nanorod catalyzed hydrogen-borrowing reactions and tert-butyl ester synthesis》 was published in Journal of Chemical Research. The article was written by Luo, Huanhuan; Yang, Yike; Yang, Bobin; Xu, Zhaojun; Wang, Dawei. The article contains the following contents:

Silver/manganese dioxide (Ag@MnO2) nanorods are synthesized and characterized by SEM, transmission electron microscopy, energy dispersive X-ray spectroscopy, X-ray powder diffraction, and XPS. It was discovered that Ag@MnO2 nanorods can realize hydrogen-borrowing reactions in high yields and are also effective for the synthesis of tert-Bu esters from aryl cyanides and tert-Bu hydroperoxide in a short period of time. Mechanistic experiments revealed that this catalytic system acts as a Lewis acid in hydrogen-borrowing reactions, while the synthesis of tert-Bu esters occurs through a radical pathway. This is the first report on the excellent catalytic activity of Ag@MnO2 nanorods as a catalyst. In the experimental materials used by the author, we found 2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5Related Products of 31938-07-5)

2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5) has been used in the synthesis of a series of aminoethylbiphenyls, novel 5-HT7 receptor ligands or 2-(1-cyano-1-(3-bromophenyl))methylidene-3-phenylthiazolidine-4,5-dione.Related Products of 31938-07-5

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Name: 4-BromobenzonitrileIn 2022 ,《Characterization of Radioiodinated Diaryl Oxadiazole Derivatives as SPECT Probes for Detection of Myelin in Multiple Sclerosis》 appeared in ACS Chemical Neuroscience. The author of the article were Watanabe, Hiroyuki; Maekawa, Rinka; Iikuni, Shimpei; Kakae, Masashi; Matsuo, Nagisa; Shirakawa, Hisashi; Kaneko, Shuji; Ono, Masahiro. The article conveys some information:

Multiple sclerosis (MS) is an intractable disease of the central nervous system that results from destruction of the myelin sheath. Direct measurement of de- and remyelination is required for monitoring the disease stage of MS, but no useful method has been established. In this study, we characterized four diaryl oxadiazole derivatives as novel myelin-imaging probes for single photon emission computed tomog. (SPECT). All the diaryl oxadiazole derivatives penetrated the blood-brain barrier in normal mice. Among them, the highest ratio of radioactivity accumulation in the white matter (myelin-rich region) against the gray matter (myelin-deficient region) was observed at 60 min postinjection of [125I]1,3,4-PODP-DM in ex vivo autoradiog. using normal mice. In the blocking study with ex vivo autoradiog., the radioactivity accumulation of [125I]1,3,4-PODP-DM in the white matter markedly reduced. [125I]1,3,4-PODP-DM detected demyelination in the ex vivo autoradiog. images of not only the spinal cord of the exptl. autoimmune encephalomyelitis mice but also the brain after lysophosphatidylcholine (LPC) injection. In addition, [123I]1,3,4-PODP-DM could image LPC-induced demyelination in the mouse brain with SPECT. These results suggest that [123I]1,3,4-PODP-DM may be a potential SPECT probe for imaging myelin in MS. In addition to this study using 4-Bromobenzonitrile, there are many other studies that have used 4-Bromobenzonitrile(cas: 623-00-7Name: 4-Bromobenzonitrile) was used in this study.

4-Bromobenzonitrile(cas: 623-00-7) has been used in the synthesis of 4-iodobenzonitrile via photo-induced aromatic Finkelstein iodination reaction.Name: 4-Bromobenzonitrile It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.

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Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Category: nitriles-buliding-blocksIn 2012 ,《Quantitative structure-property relationships studies on free-radical polymerization chain-transfer constants for styrene》 appeared in Journal of Applied Polymer Science. The author of the article were Xu, Jie; Wang, Lei; Zhang, Hui; Shen, Xiaolin; Liang, Guijie. The article conveys some information:

Quant. structure-property relationships (QSPR) studies were performed for kinetic chain-transfer constants of 90 agents on styrene polymerization at 60°. By using stepwise multi-linear regression anal. (MLRA) and artificial neural network (ANN), linear and nonlinear models containing seven descriptors were obtained with R2 of 0.7866 and 0.8661 for the training set, resp. The reliability of the proposed models was validated through the test set. The descriptors involved in the models are related to the mol. conformational changes and some functional groups. As these descriptors are directly calculated from the mol. structure, the proposed models can be employed to estimate the chain-transfer constants for styrene. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5Category: nitriles-buliding-blocks)

2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5) has been used in the synthesis of a series of aminoethylbiphenyls, novel 5-HT7 receptor ligands or 2-(1-cyano-1-(3-bromophenyl))methylidene-3-phenylthiazolidine-4,5-dione.Category: nitriles-buliding-blocks

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Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Electric Literature of C8H6BrNIn 2020 ,《Synthesis and antitumor activity of novel gibberellin derivatives with tetracyclic diterpenoid skeletons》 appeared in Medicinal Chemistry Research. The author of the article were Zhu, Shi-ying; Luo, Fa-zeng; Sun, Ping-Hua. The article conveys some information:

Abstract: Gibberellic acid (GA3) is a tetracyclic diterpene compound which displays interesting bioactivities. Recently, its potential use for preparing antitumor drug leads has been highlighted, and various modification methods of GA3 have been reported. Aiming at investigating GA3 derivatives with potential antitumor activities, ring distortion of GA3 under different conditions was carried out, and this was followed with amidation or substitution, yielding four series of derivatives The chem. structure of these compounds were analyzed by 1H-NMR, 13C-NMR, HRMS, FTIR and polarimetry, and SXRD was employed to further confirm the spatial configurations of derivatives 3c and 7d. The antitumor activities of three series of derivatives were evaluated by using MTT assay and ELISA. Results shows that, among amide derivatives, compounds with a saturated linear amide showed better activity than those with an aromatic amide. Among ester derivatives, compounds with a meta-substituted benzyl group showed better activities than those with a para-substituted benzyl group. The antitumor activity of ester derivatives might possibly be linked with the inhibition of FGFR1 activation and KDR activation. Overall, this study discussed how the antitumor activity of GA3 was formed, thereby assisting the future design of more effective active GA3 derivatives [graphic not available: see fulltext]. In the part of experimental materials, we found many familiar compounds, such as 4-Cyanobenzyl bromide(cas: 17201-43-3Electric Literature of C8H6BrN)

4-Cyanobenzyl bromide(cas: 17201-43-3) can reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile. And it may be used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile.Electric Literature of C8H6BrN

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Akkoc, Mitat; Bugday, Nesrin; Altin, Serdar; Yasar, Sedat published an article in 2021. The article was titled 《Magnetite@MCM-41 nanoparticles as support material for Pd-N-heterocyclic carbene complex: A magnetically separable catalyst for Suzuki-Miyaura reaction》, and you may find the article in Applied Organometallic Chemistry.Application In Synthesis of 2-Bromobenzonitrile The information in the text is summarized as follows:

The magnetite@MCM-41@NHC@Pd catalyst was obtained with Pd metal bound to the NHC ligand anchored to the surface of Fe3O4@MCM-41. It was characterized by Fourier transform IR (FTIR) spectroscopy, transmission electron microscopy (TEM), X-ray diffraction (XRD), XPS, energy disperse X-ray anal. (EDX), thermogravimetric anal. (TGA), DTA, and SEM. The amount of Pd in the magnetite@MCM-41@NHC@Pd was measure by inductively coupled plasma-optical emission spectroscopy (ICP-OES) anal. The catalytic activity of magnetite@MCM-41@NHC@Pd heterogeneous catalyst done on Suzuki-Miyaura reactions of aryl halides with different substituted arylboronic acid derivatives All coupling reactions afforded excellent yields and up to 408404 turnover frequency (TOF) h-1 in the presence of 2 mg of magnetite@MCM-41@NHC@Pd catalyst (0.0564 mmol g-1, 0.01127 mmol% Pd) at room temperature in 2-propanol/H2O (1:2). Moreover, magnetite@MCM-41@NHC@Pd catalyst was recover by applying the magnet and reused for another reaction. The catalyst showed excellent structural and chem. stability and reused ten times without a substantial loss in its catalytic performance. The experimental process involved the reaction of 2-Bromobenzonitrile(cas: 2042-37-7Application In Synthesis of 2-Bromobenzonitrile)

2-Bromobenzonitrile(cas: 2042-37-7) is used as a starting material to synthesize novel benzothiophene derivatives that were found to exhibit antibacterial and antifungal activity. It is commonly employed in reactions that require an electron-rich species to carry out nucleophilic substitution (or addition) reactions.Application In Synthesis of 2-Bromobenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Sen, Arunabha; Dutta, Subhajit; Dam, Gourab K.; Samanta, Partha; Let, Sumanta; Sharma, Shivani; Shirolkar, Mandar M.; Ghosh, Sujit K. published an article in 2021. The article was titled 《Imidazolium-Functionalized Chemically Robust Ionic Porous Organic Polymers (iPOPs) toward Toxic Oxo-Pollutants Capture from Water》, and you may find the article in Chemistry – A European Journal.Quality Control of 4-Cyanobenzyl bromide The information in the text is summarized as follows:

Fabricating new and efficient materials aimed at containment of water contamination, in particular removing toxic heavy metal based oxo-anions (e. g. CrO42-, TcO4-) holds paramount importance. In this work, we report two new highly stable imidazolium based ionic porous organic polymers (iPOPs) decorated with multiple interaction sites along with electrostatics driven adsorptive removal of such oxo-anions from water. Both the iPOPs (namely, iPOP-3 and iPOP-4) exhibited rapid sieving kinetics and very high saturation uptake capacity for CrO42- anions (170 and 141 mg g-1 for iPOP-3 and iPOP-4 resp.) and ReO4- (515.5 and 350.3 mg g-1 for iPOP-3 and iPOP-4 resp.), where ReO4- anions being the non-radioactive surrogative counterpart of radioactive TcO4- ions. Noticeably, both iPOPs showed exceptional selectivity towards CrO42- and ReO4- even in presence of several other concurrent anions such as Br-, Cl-, SO42-, NO3- etc. The theor. binding energy calculations via DFT method further confirmed the preferential interaction sites as well as binding energies of both iPOPs towards CrO42- and ReO4- over all other competing anions which corroborates with the exptl. high capacity and selectivity of iPOPs toward such oxo-anions. In the experimental materials used by the author, we found 4-Cyanobenzyl bromide(cas: 17201-43-3Quality Control of 4-Cyanobenzyl bromide)

4-Cyanobenzyl bromide(cas: 17201-43-3) is a white solid. Its melting point is 113-117°C, and flash point is 125.1°C. It is insoluble in water at 20°C. It is stable under normal temperatures and pressures. It should be stored at 0-5°C.Quality Control of 4-Cyanobenzyl bromide

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Nitrile – Wikipedia,
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Rzhevskiy, Sergey A.; Topchiy, Maxim A.; Bogachev, Vasilii N.; Minaeva, Lidiya I.; Cherkashchenko, Ilia R.; Lavrov, Konstantin V.; Sterligov, Grigorii K.; Nechaev, Mikhail S.; Asachenko, Andrey F. published their research in Mendeleev Communications in 2021. The article was titled 《Solvent-free palladium-catalyzed C-O cross-coupling of aryl bromides with phenols》.Product Details of 2042-37-7 The article contains the following contents:

A new solvent-free procedure for C-O cross-coupling between phenols ArOH (Ar = Ph, 4-chlorophenyl, 2-isopropylphenyl, etc.) and aryl bromides Ar1Br (Ar1 = 4-methylphenyl, 2-cyanophenyl, 3,5-bis(trifluoromethyl)phenyl, etc.) comprising of Pd2(dba)3/ButBrettPhos catalytic system is efficient for substrates bearing donor or acceptor, as well as bulky substituents.2-Bromobenzonitrile(cas: 2042-37-7Product Details of 2042-37-7) was used in this study.

2-Bromobenzonitrile(cas: 2042-37-7) is a precursor to the quinazolinones, a class of drugs used to treat autoimmune diseases and coronary heart disease. This substrate molecule undergoes a palladium-catalyzed coupling reaction to form an aromatic ring. The light emission from this reaction can be seen in the reaction solution.Product Details of 2042-37-7

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts