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Konstantinova, Lidia S. et al. published their research in Journal of the Chemical Society in 1999 |CAS: 2510-01-2

The Article related to indenothiazine preparation, indenodithiole preparation, indenothiophene preparation, thiazine indeno preparation, dithiole indeno preparation, thiophene indeno preparation and other aspects.Synthetic Route of 2510-01-2

On April 21, 1999, Konstantinova, Lidia S.; Rakitin, Oleg A.; Rees, Charles W.; Souvorova, Ljudmila I.; Torroba, Tomas published an article.Synthetic Route of 2510-01-2 The title of the article was One-pot synthesis of indeno-1,2-thiazines, -[1,2]dithioles and thiophenes; new liquid crystalline materials. And the article contained the following:

In a search for further examples of a new type of discotic liquid crystal, the authors have examined the reactions of S2Cl2 in the presence of a chlorinating agent (NCS) and a base (Hunig’s base or DABCO), mostly in THF, with cyclopent-1-enylacetic acid (I), inden-3-ylacetic acid (II) and its nitrile (III) and 1-(dicyanomethylene)indane (IV). The cyclopentene acid I gives purple crystals of the trichlorocyclopenta[1,2]dithiole ester, the product of heterocyclic ring formation, chlorination and dehydrochlorination and, unexpectedly, conversion of the acid in THF into its 4-chlorobutyl ester. Indenylacetic acid II gives methyleneindenes, the tricyclic 1,2-dithiolone V and the deep purple thiophene VI. Indenylacetonitrile III gives E-1-(伪-chloro-伪-cyanomethylene)indane and E- and Z-1-(伪-chloro-伪-cyanomethylene)-2,3-dichloroindene and Z-2-chloro-1-(伪-cyanomethylene)indane, depending upon the precise reaction conditions. Dicyanomethylene indane IV gives 1-(dicyanomethylene)-2,3-dichloroindene (VII) and the red, thermochromic 3,9-dichloro-4-cyanoindeno[1,2-e]-1,2-thiazine; the analogous cyano-ester gives the corresponding products. On melting, crystals of VI and VII are strongly birefringent. Mechanisms are proposed for the new transformations. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).Synthetic Route of 2510-01-2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Chen, Xiaohang et al. published their research in Chinese Journal of Chemistry in 2009 |CAS: 2510-01-2

The Article related to dicyanoethylaminodiethylfluorene moiety blue light emitting star shaped compound, dual fluorescence blue light emitting star shaped compound oled, Physical Organic Chemistry: Absorption, Emission, Reflection, and Scattering Spectra (Ultraviolet and Visible, Infrared and Fourier Transform Infrared, Raman, Microwave, Photoelectron, Fluorescence, Phosphorescence, etc.) and other aspects.Synthetic Route of 2510-01-2

On May 31, 2009, Chen, Xiaohang; Chen, Xiaopeng; Zhao, Zujin; Lu, Ping; Wang, Yanguang published an article.Synthetic Route of 2510-01-2 The title of the article was 2,4-dicyano-3-diethylamino-9,9-diethylfluorene based blue light-emitting star-shaped compounds: synthesis and properties. And the article contained the following:

Two new star-shaped mols. I and II containing a triphenylamine/benzene moiety as the central core and three 2,4-dicyano-3-diethylamino-9,9-diethylfluorene moieties as the peripheral functional groups were synthesized and characterized. Charge transfer properties for these compounds were observed in photophys. experiments due to their D-A mol. structure. I presented dual fluorescence in high polar solvents. Moreover, these compounds exhibited moderate fluorescence and high thermal stabilities, indicating their potential application to blue light emitting materials. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).Synthetic Route of 2510-01-2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Estrada, Leandro A. et al. published their research in Physical Chemistry Chemical Physics in 2016 |CAS: 2510-01-2

The Article related to indanylidene malononitrile fluorenylidene malononitrile excited state deactivation mechanism nonradiative, Physical Organic Chemistry: Absorption, Emission, Reflection, and Scattering Spectra (Ultraviolet and Visible, Infrared and Fourier Transform Infrared, Raman, Microwave, Photoelectron, Fluorescence, Phosphorescence, etc.) and other aspects.Reference of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile

Estrada, Leandro A.; Frances-Monerris, Antonio; Schapiro, Igor; Olivucci, Massimo; Roca-Sanjuan, Daniel published an article in 2016, the title of the article was Mechanism of excited state deactivation of indan-1-ylidene and fluoren-9-ylidene malononitriles.Reference of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile And the article contains the following content:

Herein, we report complementary computational and exptl. evidence supporting the existence, for indan-1-ylidene malononitrile and fluoren-9-ylidene malononitrile, of a non-radiative decay channel involving double bond isomerization motion. The results of UV-Vis transient absorption spectroscopy highlight that the decay takes place within hundreds of picoseconds. In order to understand the related mol. mechanism, photochem. reaction paths were computed by employing multiconfigurational quantum chem. The results indicate that the excited state deactivation occurs via concerted double bond twisting of the dicyanovinyl (DCV) unit coupled with a pyramidalization of its substituted carbon. It is also shown that the observed differences in the excited state lifetimes when passing from indan-1-ylidene malononitrile to fluoren-9-ylidene are associated with the change in the topog. of the conical intersection driving the decay from intermediate to sloped, resp. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).Reference of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Xie, Ya-Sa et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2020 |CAS: 2510-01-2

The Article related to functionalized fluorene fluorenone preparation, indanylidene malononitrile morita baylis hillman carbonate benzannulation metal free, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Dibenzocyclobutenes, Acenaphthenes, Fluorenes, and Their Benzo Analogs, Such As Fluoranthenes and other aspects.Electric Literature of 2510-01-2

Xie, Ya-Sa; Huang, Run-Feng; Li, Ran; Zhang, Chuan-Bao; Fu, Ji-Ya; Zhao, Li-Li; Yuan, Jin-Fang published an article in 2020, the title of the article was Metal-free [3+3] benzannulation of 1-indanylidene-malononitrile with Morita-Baylis-Hillman carbonates: direct access to functionalized fluorene and fluorenone derivatives.Electric Literature of 2510-01-2 And the article contains the following content:

An efficient [3+3] benzannulation of Morita-Baylis-Hillman carbonates with 1-indanylidenemalononitrile was achieved under metal-free reaction conditions selectively delivering a wide range of functional multi-substituted fluorene I (R1 = H, 7-F, 6-Me, 6-OMe; R2 = H, 4-F, 3-Br, etc.) or fluorenone compounds II in high yields, resp. (up to 86% yield). Moreover, experiments and quantum chem. calculations were also performed to study the mechanism of the transformation. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).Electric Literature of 2510-01-2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Fu, Jiya et al. published their patent in 2021 |CAS: 2510-01-2

The Article related to axial chiral fluoramine phenol derivative preparation tandem one pot, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Dibenzocyclobutenes, Acenaphthenes, Fluorenes, and Their Benzo Analogs, Such As Fluoranthenes and other aspects.Computed Properties of 2510-01-2

On September 3, 2021, Fu, Jiya; Yuan, Jinfang; Li, Ran; Deng, Yihang; Wang, Yanbo; Zhu, Junyan; Ding, Tao published a patent.Computed Properties of 2510-01-2 The title of the patent was Preparation of axially chiral fluoramine phenol derivatives. And the patent contained the following:

The invention discloses a preparation of axially chiral fluoramine phenol derivatives, which has the advantages of high efficiency, convenience, low cost and good application prospect. Axially chiral fluoramine phenol derivatives are shown in structure I, wherein R1 is selected from: CN or CO2Me; R2 is selected from substituted or unsubstituted Ph, substituted or unsubstituted pyridyl, substituted or unsubstituted furanyl, substituted or unsubstituted naphthyl. Axially chiral fluoramine phenol derivatives were prepared via one pot multi-step reaction of 2-benzofuranone derivatives and 1-indene methylene malononitrile derivatives The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).Computed Properties of 2510-01-2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Chen, Xiao-Hang et al. published their research in Chemistry Letters in 2008 |CAS: 2510-01-2

The Article related to aminodicyanodiethylfluorene preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Dibenzocyclobutenes, Acenaphthenes, Fluorenes, and Their Benzo Analogs, Such As Fluoranthenes and other aspects.HPLC of Formula: 2510-01-2

On June 5, 2008, Chen, Xiao-Hang; Zhao, Zujin; Liu, Yang; Lu, Ping; Wang, Yan-Guang published an article.HPLC of Formula: 2510-01-2 The title of the article was Synthesis and properties of 1-(4-aminophenyl)-2,4-dicyano-3-diethylamino-9,9-diethylfluorenes: potential fluorescent material. And the article contained the following:

Four fluorenes bearing two electron donors and two electron acceptors were synthesized. These compounds were found to emit blue fluorescence in both solution and solid states. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).HPLC of Formula: 2510-01-2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Bhajammanavar, Vinod et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2022 |CAS: 2510-01-2

The Article related to alkylidene malononitrile cyclopentene dione quinidine catalyst diastereoselective tandem spirocyclization, imino spirononene carbonitrile preparation, Heterocyclic Compounds (One Hetero Atom): Benzopyrans (Including Coumarins, Isocoumarins, Chromones, Benzopyrones, Dibenzopyrans, and Other Arenopyrans) and other aspects.Recommanded Product: 2510-01-2

Bhajammanavar, Vinod; Mallik, Sumitava; Choutipalli, Venkata Surya Kumar; Subramanian, Venkatesan; Baidya, Mahiuddin published an article in 2022, the title of the article was Diastereoselective access to [4,4]-carbospirocycles: governance of thermodynamic enolates with an organocatalyst in vinylogous cascade annulation.Recommanded Product: 2510-01-2 And the article contains the following content:

A vinylogy concept driven annulation strategy was developed to access [4,4]-carbospirocycles from alkylidene malononitriles and cyclopentene-1,3-diones. The reaction was catalyzed by an inexpensive organocatalyst and products with three stereocenters were obtained as a single diastereomer in high yields. The spiro-selectivity originated from the reaction of the thermodn. enolate intermediate which is fundamentally intriguing. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).Recommanded Product: 2510-01-2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Magar, Rupali L. et al. published their research in Journal of Heterocyclic Chemistry in 2015 |CAS: 75629-62-8

The Article related to indole preparation gn3 reusability catalyst mechanism nucleophile condensation reaction, Heterocyclic Compounds (One Hetero Atom): Benzopyrans (Including Coumarins, Isocoumarins, Chromones, Benzopyrones, Dibenzopyrans, and Other Arenopyrans) and other aspects.Recommanded Product: 2-((1H-Indol-3-yl)methylene)malononitrile

Magar, Rupali L.; Thorat, Prashant B.; Waware, Jagdish L.; More, Rameshwar R.; Solanke, Usha A.; Patil, Bhagwan R.; Pawar, Rajendra P. published an article in 2015, the title of the article was Synthesis of Some Novel 3-Substituted Indole Derivatives Using Polyamine Functionalized Heterogeneous Catalyst.Recommanded Product: 2-((1H-Indol-3-yl)methylene)malononitrile And the article contains the following content:

In present work, we have described the use of polyamine solid supported GN3 as catalyst in organic transformations using 1H-indole-3-carbaldehyde. To the best of our knowledge, reports for the synthesis of chromene substituted at 3C position of indole are extremely rare in the literature. The polyamine functionalized immobilized silica (GN3) was found to be an excellent catalyst for synthesis of novel 2-amino-4-(1H-indol-3-yl)-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile derivatives and Knoevenagel condensation. Catalyst GN3 was able to furnish excellent yield for a wide range of products. Moreover, the catalyst was reusable and reused for several times without loss of its catalytic activity. The experimental process involved the reaction of 2-((1H-Indol-3-yl)methylene)malononitrile(cas: 75629-62-8).Recommanded Product: 2-((1H-Indol-3-yl)methylene)malononitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Buckle, Derek R. et al. published their research in Journal of the Chemical Society in 1991 |CAS: 138801-92-0

The Article related to cromakalim analog preparation conformation, Heterocyclic Compounds (One Hetero Atom): Benzopyrans (Including Coumarins, Isocoumarins, Chromones, Benzopyrones, Dibenzopyrans, and Other Arenopyrans) and other aspects.Application of 138801-92-0

On November 30, 1991, Buckle, Derek R.; Eggleston, Drake S.; Houge-Frydrych, Catherine S. V.; Pinto, Ivan L.; Readshaw, Simon A.; Smith, David G.; Webster, Richard A. B. published an article.Application of 138801-92-0 The title of the article was Conformational and steric modifications of the pyran ring of the potassium channel activator cromakalim. And the article contained the following:

The syntheses of analogs of the novel smooth muscle relaxant cromakalim, (I), in which the C-2 Me groups have been successively replaced by hydrogen, are described and the relative stereochem. of the two corresponding, isomeric monomethyl compounds, unambiguously assigned by 1H NMR spectroscopic techniques. Single-crystal x-ray anal. of the 2伪-monomethyl compound showed that it existed in a distorted half-chair conformation in the solid state and confirmed the relative orientation of the C-2, C-3 and C-4 substituents. The 2尾-Me isomer appeared to exist in a single conformation in solution, with the pyran ring adopting a half-chair conformation and with all the substituents in this ring occupying a pseudoequatorial position. The solution behavior of the 2伪-Me isomer is more complex, however, although it seems likely to exist as a distorted half-chair conformer similar to that found in the solid state. The syntheses of two related benzoxepines are also described. All compounds were less potent than cromakalim itself, which is consistent with the view that di-Me substitution at C-2 is essential for optimal activity. The experimental process involved the reaction of 4-Oxochroman-6-carbonitrile(cas: 138801-92-0).Application of 138801-92-0

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Wang, Xueqing et al. published their patent in 2013 |CAS: 138801-92-0

The Article related to naphthyridine preparation chemokine receptor antagonist treatment pain, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Name: 4-Oxochroman-6-carbonitrile

On January 24, 2013, Wang, Xueqing; Meyer, Michael; Yao, Betty; Guo, Tao; Wei, Guo Pingrobert; Wang, Lijuan Jane published a patent.Name: 4-Oxochroman-6-carbonitrile The title of the patent was Preparation of 1,6-naphthyridine derivatives as chemokine receptor antagonists. And the patent contained the following:

The invention relates to 1,6-naphthyridine derivatives of formula I and pharmaceutically acceptable salts, solvates and prodrugs thereof as chemokine receptor antagonists; their preparation and use in the treatment of pain. Compounds of formula I wherein X1 is CR1 and N; X2 is CR2 and N; X3 is CR3 and N; R1, R2 and R3 are independently H, CN, halo, etc.; G1 is NR4R5, substituted pyridinyl, etc.; R4 is H,(halo)alkyl, alkoxyalkyl, etc.; R5 is (un)substituted heterocyclyl, Ph, naphthyl, cycloalkyl, etc.; and pharmaceutically acceptable salts, solvates and prodrugs thereof, are claimed. Example compound II 鈥?succinate was prepared by a multistep procedure (procedure given). All the invention compounds were evaluated for their chemokine receptor antagonistic activity. From the assay, it was determined that example compound II 鈥?succinate exhibited Kb value ranged from 0.003 渭M to 0.006 渭M. The experimental process involved the reaction of 4-Oxochroman-6-carbonitrile(cas: 138801-92-0).Name: 4-Oxochroman-6-carbonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts