Tag: 200-300

N,S-Codoped Carbon Shells Embedded with Ultrafine Co NPs for Reductive Amination with Formic Acid was written by Guo, Haotian;Wang, Bowei;Qiu, Pengzhi;Gao, Ruixiao;Sun, Mingming;Chen, Ligong. And the article was included in ACS Sustainable Chemistry & Engineering in 2019.Quality Control of 4-(Benzylamino)benzonitrile This article mentions the following:

Herein, N,S-codoped carbon materials embedded with ultrafine and well-distributed Co nanoparticles (1.14 weight % Co) were prepared through pyrolysis of the hybrids of SNW-1 and Co(Ac)₂ coated with glucose. It was observed by TEM and x-ray diffraction that Co nanoparticles (NPs) were entrapped in doped carbon shells uniformly. The glucose coating presented a significant impact on the size distribution of Co NPs and doped modes of heteroatoms, especially the S species. The catalyst displayed outstanding activity for catalytic transfer hydrogenation (CTH) with formic acid under the base-free system. Encouragingly, diverse secondary amines were produced in excellent yields through the domino reaction of hydrogenation and reductive amination. Remarkably, the catalyst with ultrafine Co NPs showed good durability under harsh reaction conditions and displayed no significant loss in both activity and selectivity in 5 runs. This was attributed to the protection of constructed N,S dual-doped carbon shells. Hence, we offer an alternative strategy for the construction of dual-doped carbon materials trapped with ultrafine transition metal, which can be further applied in various catalytic processes. In the experiment, the researchers used many compounds, for example, 4-(Benzylamino)benzonitrile (cas: 10282-32-3Quality Control of 4-(Benzylamino)benzonitrile).

4-(Benzylamino)benzonitrile (cas: 10282-32-3) belongs to nitriles. Trimerization of aromatic nitriles requires harsh reaction conditions, high temperatures, long reaction times, and pressure. In addition, Nitriles can react with alkynes, which leads to an increase in carbon chain length (carbocyanation).Quality Control of 4-(Benzylamino)benzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nonlinear optical properties of retinal derivatives was written by Ikeda, Hidetsugu;Kawabe, Yutaka;Sakai, Toshio;Kawasaki, Kenji. And the article was included in Chemistry Letters in 1989.Synthetic Route of C18H10N2 This article mentions the following:

Retinal derivatives I [Z = C(CN)C₆H₄NO₂–p, C(CN)₂, NC₆H₄NMe₂–p] with electron donors or acceptors were synthesized and their 2nd order nonlinear optical properties were investigated by elec. field induced 2nd harmonic generation (EFISH) method. Retinal derivatives were found to have large 2nd order optical nonlinearities. In the experiment, the researchers used many compounds, for example, 2-(Anthracen-9-ylmethylene)malononitrile (cas: 55490-87-4Synthetic Route of C18H10N2).

2-(Anthracen-9-ylmethylene)malononitrile (cas: 55490-87-4) belongs to nitriles. Nitrile carbon shifts are in the range of 115–125 ppm whereas in isonitriles the shifts are around 155–165 ppm. In addition, Nitriles can react with alkynes, which leads to an increase in carbon chain length (carbocyanation).Synthetic Route of C18H10N2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Formal Substitution of Bromocyclopropanes with Nitrogen Nucleophiles was written by Banning, Joseph E.;Gentillon, Jacob;Ryabchuk, Pavel G.;Prosser, Anthony R.;Rogers, Andrew;Edwards, Andrew;Holtzen, Andrew;Babkov, Ivan A.;Rubina, Marina;Rubin, Michael. And the article was included in Journal of Organic Chemistry in 2013.Recommanded Product: 10282-32-3 This article mentions the following:

A highly chemo- and diastereoselective protocol toward amino-substituted donor-acceptor cyclopropanes via the formal nucleophilic displacement in bromocyclopropanes is described. A wide range of N-nucleophiles, including carboxamides, sulfonamides, azoles, and anilines, can be efficiently employed in this transformation, providing expeditious access to stereochem. defined and densely functionalized cyclopropylamine derivatives In the experiment, the researchers used many compounds, for example, 4-(Benzylamino)benzonitrile (cas: 10282-32-3Recommanded Product: 10282-32-3).

4-(Benzylamino)benzonitrile (cas: 10282-32-3) belongs to nitriles. The R-C-N bond angle in and nitrile is 180° which give a nitrile functional group a linear shape. Both the carbon and the nitrogen are sp hydridized which leaves them both with two p orbitals which overlap to form the two π bond in the triple bond. Nitriles are susceptible to hydrogenation over diverse metal catalysts. The reaction can afford either the primary amine (RCH2NH2) or the tertiary amine ((RCH2)3N), depending on conditions.Recommanded Product: 10282-32-3

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Hypervalent Iodine(III)-Catalyzed Epoxidation of β-Cyanostyrenes was written by Mangaonkar, Saeesh R.;Singh, Fateh V.. And the article was included in Synthesis in 2019.Computed Properties of C18H10N2 This article mentions the following:

A convenient approach for the synthesis of β-cyanoepoxides is illustrated by iodine(III)-catalyzed epoxidation of electron-deficient β-cyanostyrenes, wherein the active catalytic iodine(III) species was generated in situ. The epoxidation of β-cyanostyrenes was performed using 10 mol% PhI as precatalyst in the presence of 2.0 equiv oxone as an oxidant and 2.4 equiv of TFA as an additive at room temperature under ultrasonic radiations. The β-cyanoepoxides were isolated in good to excellent yields in a short reaction time. In the experiment, the researchers used many compounds, for example, 2-(Anthracen-9-ylmethylene)malononitrile (cas: 55490-87-4Computed Properties of C18H10N2).

2-(Anthracen-9-ylmethylene)malononitrile (cas: 55490-87-4) belongs to nitriles. There has been no report on the microbial biosynthesis of nitriles and the physiological function of such enzymes, nor was it not even known whether aliphatic and aromatic nitriles are biological compounds or just petrochemicals. In conventional organic reductions, nitrile is reduced by treatment with lithium aluminium hydride to the amine. Reduction to the imine followed by hydrolysis to the aldehyde takes place in the Stephen aldehyde synthesis, which uses stannous chloride in acid.Computed Properties of C18H10N2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Synthesis of benzylidenemalononitrile by Knoevenagel condensation through monodisperse carbon nanotube-based NiCu nanohybrids was written by Zengin, Nursefa;Burhan, Hakan;Savk, Aysun;Goksu, Haydar;Sen, Fatih. And the article was included in Scientific Reports in 2020.Name: 2-(Anthracen-9-ylmethylene)malononitrile This article mentions the following:

Monodisperse nickel/copper nanohybrids (NiCu@MWCNT) based on multi-walled carbon nanotubes (MWCNT) were prepared for the Knoevenagel condensation of aryl and aliphatic aldehydes. The synthesis of these nanohybrids was carried out by the ultrasonic hydroxide assisted reduction method. NiCu@MWCNT nanohybrids were characterized by anal. techniques such as X-ray diffraction (XRD), XPS, transmission electron microscopy (TEM), high-resolution transmission electron microscopy (HR-TEM), and Raman spectroscopy. According to characterization results, NiCu@MWCNT showed that these nanohybrids form highly uniform, crystalline, monodisperse, colloidally stable NiCu@MWCNT nanohybrids were successfully synthesized. Thereafter, a model reaction was carried out to obtain benzylidenemalononitrile derivatives using NiCu@MWCNT as a catalyst, and showed high catalytic performance under mild conditions over 10-180 min. In the experiment, the researchers used many compounds, for example, 2-(Anthracen-9-ylmethylene)malononitrile (cas: 55490-87-4Name: 2-(Anthracen-9-ylmethylene)malononitrile).

2-(Anthracen-9-ylmethylene)malononitrile (cas: 55490-87-4) belongs to nitriles. Nitriles are polar, as indicated by high dipole moments. As liquids, they have high relative permittivities, often in the 30s. Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion.Name: 2-(Anthracen-9-ylmethylene)malononitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Synthesis, reactions, and antimicrobial activity of some fused thieno[2,3-d]yrimidine derivatives was written by Prabhu, Pradnya J.;Khombare, Rajiv T.;Kadam, Mangesh D.. And the article was included in International Journal of Chemistry (Mumbai, India) in 2013.Safety of Ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate This article mentions the following:

Novel thieno[2,3-d]pyrimidines, 4-imino-pyrimidin-3-ylamine and pyrimidon-4-ylhydrazine derivatives were prepared starting from ethyl-5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate and 5-amino-4-cyano-3-methyl-thiophene-2-carboxylic acid Et ester. The antimicrobial evaluation of the synthesized compounds showed that many of them revealed promising antimicrobial activity. In the experiment, the researchers used many compounds, for example, Ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate (cas: 58168-20-0Safety of Ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate).

Ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate (cas: 58168-20-0) belongs to nitriles. The electronic structure of nitriles is very similar to that of an alkyne with the main difference being the presence of a set of lone pair electrons on the nitrogen. Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. Both routes are green in the sense that they do not generate stoichiometric amounts of salts.Safety of Ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

A versatile cobalt catalyst for the reductive amination of carbonyl compounds with nitro compounds by transfer hydrogenation was written by Zhou, Peng;Zhang, Zehui;Jiang, Liang;Yu, Changlin;Lv, Kangle;Sun, Jie;Wang, Shuguo. And the article was included in Applied Catalysis, B: Environmental in 2017.Electric Literature of C14H12N2 This article mentions the following:

Co nanoparticles embedded in mesoporous nitrogen-doped carbon (abbreviated as Co@CN-800) were prepared and found to be resistant to acid. The Co@CN-800 catalyst was active and selective for the one-pot reductive amination of carbonyl compounds with nitro compounds by transfer hydrogenation with formic acid as the hydrogen donor, affording the corresponding secondary amines with excellent yields (89.6-99%). Both nitrogen atoms and Co nanoparticles were of great importance in the one-pot reductive amination over the Co@CN-800 catalyst by formic acid, and the protic N-H⁺ and hydridic Co-H^– were proposed to be the active species for the transfer hydrogenation reactions. Furthermore, the Co@CN-800 catalyst was highly stable without loss of its activity. In the experiment, the researchers used many compounds, for example, 4-(Benzylamino)benzonitrile (cas: 10282-32-3Electric Literature of C14H12N2).

4-(Benzylamino)benzonitrile (cas: 10282-32-3) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. Some nitriles are manufactured by heating carboxylic acids with ammonia in the presence of catalysts. This process is used to make nitriles from natural fats and oils, the products being used as softening agents in synthetic rubbers, plastics, and textiles and for making amines.Electric Literature of C14H12N2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts