Tag: M.W=100-150

An article Management of anaemia and blood in patients having neck dissections or free flaps for head and neck cancer WOS:000476865000009 published article about TRANSFUSION PREDICTION; PRIMARY SURGERY; IMPACT; RADIOTHERAPY; HEMOGLOBIN in [Rogers, S. N.] Edge Hill Univ, Fac Hlth & Social Care, Evidence Based Practice Res Ctr EPRC, St Helens Rd, Ormskirk L39 4QP, England; [Rogers, S. N.; Horisk, K.] Aintree Univ Hosp NHS Fdn Trust, Reg Maxillofacial Unit, Liverpool L9 1AE, Merseyside, England; [Groom, P.] Aintree Univ Hosp NHS Fdn Trust, Liverpool L9 1AE, Merseyside, England; [Lowe, D.] Edge Hill Univ, Fac Hlth, Evidence Based Practice Res Ctr EPRC, St Helens Rd, Ormskirk L39 4QP, England in 2019, Cited 24. The Name is 5-Norbornene-2-carbonitrile. Through research, I have a further understanding and discovery of 95-11-4. Safety of 5-Norbornene-2-carbonitrile

Our main aims were to assess haemoglobin (Hb) concentrations from preoperative assessment to discharge from hospital, and to review which patients had blood transfusions and compliance with national transfusion guidelines. We studied a consecutive series of 131 patients between October 2016 and September 2017 who had either neck dissection or resection and free microvascular tissue transfer. Half the patients had soft tissue free flaps (n=65), 26% had composite free flaps (n = 34), and 24% neck dissection only (n =32). Using the WHO definition of anaemia, 4% (1/28) of patients who had neck dissections and 19% (16/85) of those who had free flaps were anaemic preoperatively. The median (IQR) Hb at discharge was 131 (119-144) g/L for patients who had neck dissections, 103 (95-114) g/L for those who had soft free flaps, and 95 (90-104) g/L for those who had composite free flaps. No patients who had neck dissection were given a red blood cell (RBC) transfusion, whereas they were given to 26/99 (26%) of those who had free flaps. Hb concentrations were checked after each unit in 31/39 transfusions (79%). Concentrations for those who had free flaps fell by about 30 g/L from admission to operation, and only four patients were given tranexamic acid peroperatively. Postoperatively Hb remained at similar concentrations until discharge, with 23/98 (24%) given iron orally on discharge. In terms of compliance with blood transfusion guidelines there was a notable absence of the use of tranexamic acid and of iron intravenously. An increase in their use could potentially reduce the number of blood transfusions required and the postoperative incidence of anaemia, and have a favourable effect on outcomes such as complications, fatigue, and overall quality of life. (C) 2019 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Welcome to talk about 95-11-4, If you have any questions, you can contact Rogers, SN; Horisk, K; Groom, P; Lowe, D or send Email.. Safety of 5-Norbornene-2-carbonitrile

Reference:
Patent; Mitsui Chemicals, Inc.; KUMA, Shigetoshi; SAKATA, Michiharu; TOKUNAGA, Kouichi; SHIMAKAWA, Chitoshi; KAKINUMA, Naoyuki; FURUYA, Masayuki; TANAKA, Mamoru; EP2708527; (2014); A1;,
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An article Polysiloxane assisted fabrication of chiral crystal sponge coated capillary column for chiral gas chromatographic separation WOS:000503319300020 published article about METAL-ORGANIC FRAMEWORKS; ABSOLUTE STRUCTURE DETERMINATION; STATIONARY PHASES; ENANTIOMER SEPARATION; RESOLUTION; RECOGNITION; HPLC; SULFOXIDES; CATALYSIS; ISOMERS in [Wang, Zi-Meng; Yang, Cheng-Xiong] Nankai Univ, Tianjin Key Lab Mol Recognit & Biosensing, Res Ctr Analyt Sci, Coll Chem, Tianjin 300071, Peoples R China; [Yan, Xiu-Ping] Jiangnan Univ, State Key Lab Food Sci & Technol, Int Joint Lab Food Safety, Inst Analyt Food Safety,Sch Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China in 2019, Cited 51. SDS of cas: 95-11-4. The Name is 5-Norbornene-2-carbonitrile. Through research, I have a further understanding and discovery of 95-11-4

Chiral crystalline sponges (CCSs) are a recent class of chiral porous metal complexes potential in chiral recognition. Here we report the fabrication of polysiloxane OV-1701 incorporated CCS-3S (PSO/CCS-3S) coated capillary column as a novel stationary phase for gas chromatographic separation of diverse race-mates. CCS-3S with the chiral ligand of (S)-mandelic was selected as the model CCS. With the aid of polysiloxane OV-1701, PSO/CCS-3S coated capillary column gave improved resolution, broader enantiomers separation scope and much larger McReynolds constants than CCS-3S coated capillary column. Many racemates that cannot be separated on CCS-3S coated capillary column were well resolved on PSO/CCS-3S coated capillary column. The PSO/CCS-3S coated capillary column also gave wide linear range, low limit of detection, good repeatability and reproducibility, and fine inertness and anti-column bleeding properties for the separation of enantiomers. In addition, the PSO/CCS-3S coated capillary column presented better resolution for the studied racemates than commercial beta-cyclodextrin based Cyclosil B (30 m long x0.32 mm i.d. x 0.25 mu m film thickness), beta-DEX 225 (30 m long x0.25 mm i.d. x 0.25 mu m film thickness) and amino acid based Chirasil L-Val (25 m long x0.25 mm i.d. x 0.12 mu m film thickness) capillary columns. These results indicate the great potential of PSO/CCS-3S coated capillary column in separation of enantiomers. (C) 2019 Elsevier B.V. All rights reserved.

SDS of cas: 95-11-4. Welcome to talk about 95-11-4, If you have any questions, you can contact Wang, ZM; Yang, CX; Yan, XP or send Email.

Reference:
Patent; Mitsui Chemicals, Inc.; KUMA, Shigetoshi; SAKATA, Michiharu; TOKUNAGA, Kouichi; SHIMAKAWA, Chitoshi; KAKINUMA, Naoyuki; FURUYA, Masayuki; TANAKA, Mamoru; EP2708527; (2014); A1;,
Nitrile – Wikipedia,
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Recently I am researching about METAL-ORGANIC FRAMEWORKS; ABSOLUTE STRUCTURE DETERMINATION; STATIONARY PHASES; ENANTIOMER SEPARATION; RESOLUTION; RECOGNITION; HPLC; SULFOXIDES; CATALYSIS; ISOMERS, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21777074, 21775056]; Tianjin Natural Science FoundationNatural Science Foundation of Tianjin [18JCQNJC05700]; Fundamental Research Funds for Central UniversitiesFundamental Research Funds for the Central Universities. Published in ELSEVIER in AMSTERDAM ,Authors: Wang, ZM; Yang, CX; Yan, XP. The CAS is 95-11-4. Through research, I have a further understanding and discovery of 5-Norbornene-2-carbonitrile. Formula: C8H9N

Chiral crystalline sponges (CCSs) are a recent class of chiral porous metal complexes potential in chiral recognition. Here we report the fabrication of polysiloxane OV-1701 incorporated CCS-3S (PSO/CCS-3S) coated capillary column as a novel stationary phase for gas chromatographic separation of diverse race-mates. CCS-3S with the chiral ligand of (S)-mandelic was selected as the model CCS. With the aid of polysiloxane OV-1701, PSO/CCS-3S coated capillary column gave improved resolution, broader enantiomers separation scope and much larger McReynolds constants than CCS-3S coated capillary column. Many racemates that cannot be separated on CCS-3S coated capillary column were well resolved on PSO/CCS-3S coated capillary column. The PSO/CCS-3S coated capillary column also gave wide linear range, low limit of detection, good repeatability and reproducibility, and fine inertness and anti-column bleeding properties for the separation of enantiomers. In addition, the PSO/CCS-3S coated capillary column presented better resolution for the studied racemates than commercial beta-cyclodextrin based Cyclosil B (30 m long x0.32 mm i.d. x 0.25 mu m film thickness), beta-DEX 225 (30 m long x0.25 mm i.d. x 0.25 mu m film thickness) and amino acid based Chirasil L-Val (25 m long x0.25 mm i.d. x 0.12 mu m film thickness) capillary columns. These results indicate the great potential of PSO/CCS-3S coated capillary column in separation of enantiomers. (C) 2019 Elsevier B.V. All rights reserved.

Welcome to talk about 95-11-4, If you have any questions, you can contact Wang, ZM; Yang, CX; Yan, XP or send Email.. Formula: C8H9N

Reference:
Patent; Mitsui Chemicals, Inc.; KUMA, Shigetoshi; SAKATA, Michiharu; TOKUNAGA, Kouichi; SHIMAKAWA, Chitoshi; KAKINUMA, Naoyuki; FURUYA, Masayuki; TANAKA, Mamoru; EP2708527; (2014); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Gao, QW; Shang, Y; Song, FZ; Ye, JX; Liu, ZS; Li, LS; Cheng, HG; Zhou, QH in [Gao, Qianwen; Shang, Yong; Song, Fuzhen; Ye, Jinxiang; Liu, Ze-Shui; Li, Lisha; Cheng, Hong-Gang; Zhou, Qianghui] Wuhan Univ, Engn Res Ctr Organosilicon Cpds & Mat, Sauvage Ctr Mol Sci, Coll Chem & Mol Sci,Minist Educ, Wuhan 430072, Peoples R China; [Zhou, Qianghui] Wuhan Univ, Inst Adv Studies, Wuhan 430072, Peoples R China published Modular Dual-Tasked C-H Methylation via the Catellani Strategy in 2019, Cited 91. Name: 5-Norbornene-2-carbonitrile. The Name is 5-Norbornene-2-carbonitrile. Through research, I have a further understanding and discovery of 95-11-4.

We report a dual-tasked methylation that is based on cooperative palladium/norbornene catalysis. Readily available (hetero)aryl halides (39 iodides and 4 bromides) and inexpensive MeOTs or trimethylphosphate are utilized as the substrates and methylating reagent, respectively. Six types of ipso terminations can modularly couple with this ortho C-H methylation to constitute a versatile methylation toolbox for preparing diversified methylated arenes. This toolbox features inexpensive methyl sources, excellent functional-group tolerance, simple reaction procedures, and scalability. Importantly, it can be uneventfully extended to isotope-labeled methylation by switching to the corresponding reagents CD3OTs or (CH3OTs)-C-13. Moreover, this toolbox can be applied to late-stage modification of biorelevant substrates with complete stereoretention. We believe these salient and practical features of our dual-tasked methylation toolbox will be welcomed by academic and industrial researchers.

Bye, fridends, I hope you can learn more about C8H9N, If you have any questions, you can browse other blog as well. See you lster.. Name: 5-Norbornene-2-carbonitrile

Reference:
Patent; Mitsui Chemicals, Inc.; KUMA, Shigetoshi; SAKATA, Michiharu; TOKUNAGA, Kouichi; SHIMAKAWA, Chitoshi; KAKINUMA, Naoyuki; FURUYA, Masayuki; TANAKA, Mamoru; EP2708527; (2014); A1;,
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An article Modular Dual-Tasked C-H Methylation via the Catellani Strategy WOS:000490358900033 published article about PALLADIUM-CATALYZED ALKYLATION; LATE-STAGE FUNCTIONALIZATION; AROMATIC FUNCTIONALIZATION; SELECTIVE ALKYLATION; COUPLING REACTIONS; ARYL IODIDES; REAGENTS; BONDS; ACTIVATION; NORBORNENE in [Gao, Qianwen; Shang, Yong; Song, Fuzhen; Ye, Jinxiang; Liu, Ze-Shui; Li, Lisha; Cheng, Hong-Gang; Zhou, Qianghui] Wuhan Univ, Engn Res Ctr Organosilicon Cpds & Mat, Sauvage Ctr Mol Sci, Coll Chem & Mol Sci,Minist Educ, Wuhan 430072, Peoples R China; [Zhou, Qianghui] Wuhan Univ, Inst Adv Studies, Wuhan 430072, Peoples R China in 2019, Cited 91. The Name is 5-Norbornene-2-carbonitrile. Through research, I have a further understanding and discovery of 95-11-4. Computed Properties of C8H9N

We report a dual-tasked methylation that is based on cooperative palladium/norbornene catalysis. Readily available (hetero)aryl halides (39 iodides and 4 bromides) and inexpensive MeOTs or trimethylphosphate are utilized as the substrates and methylating reagent, respectively. Six types of ipso terminations can modularly couple with this ortho C-H methylation to constitute a versatile methylation toolbox for preparing diversified methylated arenes. This toolbox features inexpensive methyl sources, excellent functional-group tolerance, simple reaction procedures, and scalability. Importantly, it can be uneventfully extended to isotope-labeled methylation by switching to the corresponding reagents CD3OTs or (CH3OTs)-C-13. Moreover, this toolbox can be applied to late-stage modification of biorelevant substrates with complete stereoretention. We believe these salient and practical features of our dual-tasked methylation toolbox will be welcomed by academic and industrial researchers.

Computed Properties of C8H9N. Welcome to talk about 95-11-4, If you have any questions, you can contact Gao, QW; Shang, Y; Song, FZ; Ye, JX; Liu, ZS; Li, LS; Cheng, HG; Zhou, QH or send Email.

Reference:
Patent; Mitsui Chemicals, Inc.; KUMA, Shigetoshi; SAKATA, Michiharu; TOKUNAGA, Kouichi; SHIMAKAWA, Chitoshi; KAKINUMA, Naoyuki; FURUYA, Masayuki; TANAKA, Mamoru; EP2708527; (2014); A1;,
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An article Prevalence of diabetes and pre -diabetes in Greece. Results of the First National Survey of Morbidity and Risk Factors (EMENO) study WOS:000632552500005 published article about CARDIOVASCULAR MORBIDITY; ADULTS; POPULATION; MELLITUS; BURDEN; HEALTH; TRENDS; SAMPLE; EPIDEMIOLOGY; SURVEILLANCE in [Makrilakis, Konstantinos; Ioannidis, Ioannis; Iraklianou, Stella; Raptis, Athanasios; Sotiropoulos, Alexis; Liatis, Stavros] Hellen Diabet Assoc, Athens, Greece; [Makrilakis, Konstantinos; Liatis, Stavros] Natl & Kapodistrian Univ Athens, Med Sch, Dept Propaedeut Internal Med 1, Athens, Greece; [Kalpourtzi, Natasa; Kantzanou, Maria; Touloumi, Giota] Natl & Kapodistrian Univ Athens, Med Sch, Dept Hyg Epidemiol & Med Stat, Athens, Greece; [Ioannidis, Ioannis] Konstantopoulio Hosp, Dept Internal Med 1, Nea Ionia, Greece; [Ioannidis, Ioannis] Konstantopoulio Hosp, Diabet Ctr, Nea Ionia, Greece; [Iraklianou, Stella] Gen Hosp Tzaneio, Dept Internal Med 3, Piraeus, Greece; [Raptis, Athanasios] Natl & Kapodistrian Univ Athens, Med Sch, Attikon Univ Hosp, Dept Propaedeut Internal Med 2,Res Unit, Athens, Greece; [Raptis, Athanasios] Natl & Kapodistrian Univ Athens, Attikon Univ Hosp, Diabet Ctr, Athens, Greece; [Sotiropoulos, Alexis] Gen Hosp Nikaia Piraeus, Internal Med Dept 3, Nikea, Greece; [Sotiropoulos, Alexis] Gen Hosp Nikaia Piraeus, Diabet Ctr, Nikea, Greece; [Gavana, Magda] Aristotle Univ Thessaloniki, Med Sch, Dept Primary Hlth Care Gen Practice & Hlth Serv R, Thessaloniki, Greece; [Vantarakis, Apostolos] Univ Patras, Med Sch, Publ Hlth, Patras, Greece; [Hadjichristodoulou, Christos] Univ Thessaly, Med Fac, Dept Hyg & Epidemiol, Larisa, Greece; [Chlouverakis, Grigoris] Univ Crete, Sch Med, Lab Biostat, Iraklion, Greece; [Trypsianis, Grigoris] Democritus Univ Thrace, Med Sch, Lab Med Stat, Thrace, Greece; [Voulgari, Paraskevi V.] Univ Ioannina, Med Sch, Dept Internal Med, Ioannina, Greece; [Alamanos, Yannis] Inst Epidemiol Prevent Med & Publ Hlth, Corfu, Greece in 2021, Cited 43. The Name is 5-Norbornene-2-carbonitrile. Through research, I have a further understanding and discovery of 95-11-4. Recommanded Product: 5-Norbornene-2-carbonitrile

Aims: To report the results of the first national Health Examination Survey (HES) on the prevalence of diabetes, its pharmacologic treatment and level of control, as well as pre -diabetes in Greece. Methods: Data were derived from the National Survey of Morbidity and Risk Factors (EMENO), in a randomly selected, representative sample of the adult Greek population. Sampling weights were applied to adjust for study design and post-stratification weights to match sample age/sex distribution to the population. Non-response was adjusted by inverse probability weighting. Weighted prevalence estimates are provided. Results: A total of 4393 persons with HbA1c and/or fasting plasma glucose measurements were included. Total diabetes prevalence was 11.9% (95% CI: 10.9-12.9), known diabetes 10.4% (9.5-11.4), and unknown 1.5% (1.1-1.9), with considerable increase in older age groups and no difference between genders. Pre-diabetes prevalence was 12.4% (11.4-13.6). The majority of persons with known diabetes were receiving metformin. Of those with known diabetes (and measured HbA1c), 70.9% were well controlled (HbA1c <7.0%). Conclusions: This first representative national HES showed high prevalence of diabetes in Greece, with low prevalence of unknown diabetes. Pre-diabetes prevalence is also substantial. These results will hopefully enable national authorities develop tailored and efficient strategies for disease prevention and management. Recommanded Product: 5-Norbornene-2-carbonitrile. Bye, fridends, I hope you can learn more about C8H9N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Patent; Mitsui Chemicals, Inc.; KUMA, Shigetoshi; SAKATA, Michiharu; TOKUNAGA, Kouichi; SHIMAKAWA, Chitoshi; KAKINUMA, Naoyuki; FURUYA, Masayuki; TANAKA, Mamoru; EP2708527; (2014); A1;,
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An article In vitro assessment of major and trace element bioaccessibility in tea samples WOS:000652032600119 published article about CAMELLIA-SINENSIS L.; BLACK TEAS; ICP-MS; BIOAVAILABILITY; INFUSIONS; CALCIUM; METALS; FE; CLASSIFICATION; CONTAMINATION in [Alnaimat, Ala S.; Carmen Barciela-Alonso, Maria; Herbello-Hermelo, Paloma; Dominguez-Gonzalez, Raquel; Bermejo-Barrera, Pilar] Univ Santiago de Compostela, Dept Analyt Chem Nutr & Bromatol, Fac Chem, Grp Trace Elements Speciat & Spect GETEE,Strateg, Ave Ciencias S-N, Santiago De Compostela 15782, Spain; [Alnaimat, Ala S.] Al Hussein Bin Talal Univ, Coll Sci, Dept Chem, Maan, Jordan in 2021, Cited 46. Formula: C8H9N. The Name is 5-Norbornene-2-carbonitrile. Through research, I have a further understanding and discovery of 95-11-4

Bioaccessibility of trace elements (Li, Be, Ti, Ga, Cu, Ag, Hg, Cd, Cs, Pt, Tl, Pb, As, Cr, Co, Ni, V, Se, Sn and Sb) and major elements (Rb, Ba, Al, Fe, Zn, Si, Ca, Mg, Mn, Mo, Sr, P and K) in tea infusions has been assessed using an in vitro dialyzability protocol. Gastric simulation (using pepsin solution) and intestinal simulation (using pancreatin and bile salts) were used to perform the in vitro digestion. ICP-MS, ICP-OES and FAES were used for elements determination in digested tea leaves, their infusions and the dialyzate fractions from tea infusions. Microwaves assisted acid digestion was used for the total element determination in tea leaves, while tea infusions were prepared by brewing tea leaves for 5 min in boiling water. The LODs for elements determined in tea leaves were in the range of 0.11-656 ng g(-1) and 0.02-145.6 mu g g(-1) for trace and major elements, respectively. For elements’ determination in tea infusions, the LODs were ranged between 0.23 and 399.9 ng L-1 for trace elements and 0.2-1248 mu g L-1 for major elements. The LODs for the elements in the dialyzable fraction varied from 0.018 to 142 mu g L-1. The accuracy of the total element determination was evaluated using certified reference materials (Tea Leaves INCT-TL-1 and Rye Grass). The analytical recoveries were also assessed for analyzed elements in digested tea leaves (95-114%) and their infusions (92-115%), showing good recoveries. Among the studied elements, K was the most abundant element in tea leaves and tea infusions in almost all samples, followed by Ca, Mg, and P. Zn, Cs, and K showed the highest dialyzability percentages up to 84%, 76%, and 54%, respectively, followed by Si and Ca and K that show moderate to high dialyzability percentages. The accuracy of the dialysis process was evaluated using a mass-balance study.

Formula: C8H9N. Welcome to talk about 95-11-4, If you have any questions, you can contact Alnaimat, AS; Barciela-Alonso, MC; Herbello-Hermelo, P; Dominguez-Gonzalez, R; Bermejo-Barrera, P or send Email.

Reference:
Patent; Mitsui Chemicals, Inc.; KUMA, Shigetoshi; SAKATA, Michiharu; TOKUNAGA, Kouichi; SHIMAKAWA, Chitoshi; KAKINUMA, Naoyuki; FURUYA, Masayuki; TANAKA, Mamoru; EP2708527; (2014); A1;,
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Pews-Davtyan, A; Scharnagl, FK; Hertrich, MF; Kreyenschulte, C; Bartling, S; Lund, H; Jackstell, R; Beller, M in [Pews-Davtyan, Anahit; Scharnagl, Florian Korbinian; Hertrich, Maximilian Franz; Kreyenschulte, Carsten; Bartling, Stephan; Lund, Henrik; Jackstell, Ralf; Beller, Matthias] Univ Rostock, Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany published Biomolecule-derived supported cobalt nanoparticles for hydrogenation of industrial olefins, natural oils and more in water in 2019, Cited 62. Category: nitriles-buliding-blocks. The Name is 5-Norbornene-2-carbonitrile. Through research, I have a further understanding and discovery of 95-11-4.

Catalytic hydrogenation of olefins using noble metal catalysts or pyrophoric RANEY (R) nickel is of high importance in the chemical industry. From the point of view of green and sustainable chemistry, design and development of Earth-abundant, less toxic, and more environmentally friendly catalysts are highly desirable. Herein, we report the convenient preparation of active cobalt catalysts and their application in hydrogenations of a wide range of terminal and internal carbon-carbon double bonds in water under mild conditions. Catalysts are prepared on multi-gram scale by pyrolysis of cobalt acetate and uracil, guanine, adenine or l-tryptophan. The most active material Co-Ura/C-600 showed good productivity in industrially relevant hydrogenation of diisobutene to isooctane and in natural oil hardening.

Welcome to talk about 95-11-4, If you have any questions, you can contact Pews-Davtyan, A; Scharnagl, FK; Hertrich, MF; Kreyenschulte, C; Bartling, S; Lund, H; Jackstell, R; Beller, M or send Email.. Category: nitriles-buliding-blocks

Reference:
Patent; Mitsui Chemicals, Inc.; KUMA, Shigetoshi; SAKATA, Michiharu; TOKUNAGA, Kouichi; SHIMAKAWA, Chitoshi; KAKINUMA, Naoyuki; FURUYA, Masayuki; TANAKA, Mamoru; EP2708527; (2014); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

An article Modular Dual-Tasked C-H Methylation via the Catellani Strategy WOS:000490358900033 published article about PALLADIUM-CATALYZED ALKYLATION; LATE-STAGE FUNCTIONALIZATION; AROMATIC FUNCTIONALIZATION; SELECTIVE ALKYLATION; COUPLING REACTIONS; ARYL IODIDES; REAGENTS; BONDS; ACTIVATION; NORBORNENE in [Gao, Qianwen; Shang, Yong; Song, Fuzhen; Ye, Jinxiang; Liu, Ze-Shui; Li, Lisha; Cheng, Hong-Gang; Zhou, Qianghui] Wuhan Univ, Engn Res Ctr Organosilicon Cpds & Mat, Sauvage Ctr Mol Sci, Coll Chem & Mol Sci,Minist Educ, Wuhan 430072, Peoples R China; [Zhou, Qianghui] Wuhan Univ, Inst Adv Studies, Wuhan 430072, Peoples R China in 2019, Cited 91. Computed Properties of C8H9N. The Name is 5-Norbornene-2-carbonitrile. Through research, I have a further understanding and discovery of 95-11-4

We report a dual-tasked methylation that is based on cooperative palladium/norbornene catalysis. Readily available (hetero)aryl halides (39 iodides and 4 bromides) and inexpensive MeOTs or trimethylphosphate are utilized as the substrates and methylating reagent, respectively. Six types of ipso terminations can modularly couple with this ortho C-H methylation to constitute a versatile methylation toolbox for preparing diversified methylated arenes. This toolbox features inexpensive methyl sources, excellent functional-group tolerance, simple reaction procedures, and scalability. Importantly, it can be uneventfully extended to isotope-labeled methylation by switching to the corresponding reagents CD3OTs or (CH3OTs)-C-13. Moreover, this toolbox can be applied to late-stage modification of biorelevant substrates with complete stereoretention. We believe these salient and practical features of our dual-tasked methylation toolbox will be welcomed by academic and industrial researchers.

Computed Properties of C8H9N. Welcome to talk about 95-11-4, If you have any questions, you can contact Gao, QW; Shang, Y; Song, FZ; Ye, JX; Liu, ZS; Li, LS; Cheng, HG; Zhou, QH or send Email.

Reference:
Patent; Mitsui Chemicals, Inc.; KUMA, Shigetoshi; SAKATA, Michiharu; TOKUNAGA, Kouichi; SHIMAKAWA, Chitoshi; KAKINUMA, Naoyuki; FURUYA, Masayuki; TANAKA, Mamoru; EP2708527; (2014); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Name: 5-Norbornene-2-carbonitrile. I found the field of Toxicology very interesting. Saw the article Development of a defined approach for eye irritation or serious eye damage for liquids, neat and in dilution, based on cosmetics Europe analysis of in vitro STE and BCOP test methods published in 2019, Reprint Addresses Adriaens, E (corresponding author), Adriaens Consulting BVBA, Bellemdorpweg 95, B-9881 Aalter, Belgium.. The CAS is 95-11-4. Through research, I have a further understanding and discovery of 5-Norbornene-2-carbonitrile.

The focus of Cosmetics Europe’s programme on serious eye damage/eye irritation is on development of testing strategies and defined approaches for identification of ocular effects of chemicals in the context of OECD’s Guidance Document on an Integrated Approach on Testing and Assessment (IATA) for Serious Eye Damage and Eye Irritation. Cosmetics Europe created a comprehensive database of chemicals for which in vitro data are available with corresponding historical in vivo Draize eye data. This database allowed further exploration of the initially proposed strategies from the CON4EI project and to identify opportunities for refinement. The current analysis focused on the development of a defined approach, applicable to liquid non-surfactant chemicals, neat and in dilution, that can distinguish between the three UN GHS categories (Cat. 1, Cat. 2, and No Cat.). Combining the modified-protocol Short Time Exposure (STE) test method (OECD TG 491 with extension to highly volatile substances) with the Bovine Corneal Opacity and Permeability Laser Light-Based Opacitometer (BCOP LLBO) test method in a Bottom-Up approach identified 81.2% Cat. 1, 56.3% Cat. 2, and 85.3% No. Cat correctly, with an NPV of 96.7% and a PPV of 68.6%. Therefore, the performance of the defined approach was better than the standalone test methods.

Name: 5-Norbornene-2-carbonitrile. Welcome to talk about 95-11-4, If you have any questions, you can contact Alepee, N; Adriaens, E; Abo, T; Bagley, D; Desprez, B; Hibatallah, J; Mewes, K; Pfannenbecker, U; Sala, A; Van Rompay, AR; Verstraelen, S; McNamee, P or send Email.

Reference:
Patent; Mitsui Chemicals, Inc.; KUMA, Shigetoshi; SAKATA, Michiharu; TOKUNAGA, Kouichi; SHIMAKAWA, Chitoshi; KAKINUMA, Naoyuki; FURUYA, Masayuki; TANAKA, Mamoru; EP2708527; (2014); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts