Tag: M.W=100-150

Tong, Yue published the artcilePhotocatalytic redox-neutral arylation of cyclopropanols with cyanoarenes via radical-mediated C-C and C-CN bond cleavage, Recommanded Product: Phthalonitrile, the main research area is cyclopropanol cyanoarene bond cleavage photocatalytic redox neutral arylation.

β-Arylated ketones widely exist in many biol. active mols. and natural products. Herein, we describe a photocatalytic redox-neutral arylation of cyclopropanols with cyanoarenes via radical-mediated C-C and C-CN bond cleavage to afford various β-arylated ketones. This mild and external oxidant-free approach showed good compatibility with a range of cyclopropanols and cyanoarenes and accomplished absolute regioselective control for the precise functionalization of pyridines via the C-CN bond cleavage of 4-cyanopyridines. Remarkably, this photocatalytic ring-opening of cyclopropanols was enabled by proton-coupled electron transfer (PCET) activation using an oxidized photocatalyst.

Organic Chemistry Frontiers published new progress about Arylation (neutral). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Recommanded Product: Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Qi, Xiao-Lei published the artcileSynthesis and BK channel-opening activity of 2-amino-1,3-thiazole derivatives, Formula: C7H6N2, the main research area is aminothiazole synthesis BK channel opening SAR; BK channels; Openers; SAR; Synthesis; Thiazole.

A series of 2-amino-5-arylmethyl- or 5-heteroarylmethyl-1,3-thiazole derivatives were synthesized and evaluated for BK channel-opening activities in cell-based fluorescence assay and electrophysiol. recording. The assay results indicated that the activities of the investigated compounds were influenced by the physicochem. properties of the substituent at benzene ring.

Bioorganic & Medicinal Chemistry Letters published new progress about Bioelectric current. 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Formula: C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Galani, Sunil M. published the artcileEnhanced Thermocatalytic Activity of Porous Yellow ZnO Nanoflakes: Defect- and Morphology-Induced Perspectives, Application In Synthesis of 100-70-9, the main research area is thermocatalysis porous yellow zinc oxide nanoflake defect morphol; heterogeneous catalysis; nanostructures; oxygen vacancies; tetrazole; zinc oxide.

A simple and effective strategy is reported for the synthesis of yellow ZnO (Y-ZnO) nanostructures with abundant O vacancies on a large scale, through the sulfidation of ZnO followed by calcination. The developed strategy allows retention of the overall morphol. of Y-ZnO compared with pristine ZnO and the extent of O vacancies can be tuned. The influence of O deficiencies, the extent of defect sites, and the morphol. of ZnO on its solution-phase thermocatalytic activity was evaluated in the synthesis of 5-substituted-1H-tetrazoles with different nitriles and Na azide. A reasonable enhancement in the reaction rate was achieved by using Y-ZnO nanoflakes (Y-ZnO NFs) as a catalyst in place of pristine ZnO NFs. The reaction was complete within 6 h at 110° with Y-ZnO NFs, whereas it took 14 h at 120° with pristine ZnO NFs. The catalyst is easy to recycle without a significant loss in catalytic activity.

Chemistry – An Asian Journal published new progress about Catalysis (thermo-). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Application In Synthesis of 100-70-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kalyani, Adula published the artcilePalladium catalyzed nitrile insertion and cyanation of biindoles: Synthesis of indole fused α-carboline scaffolds via double C-H activation, SDS of cas: 100-70-9, the main research area is indole fused alpha carboline preparation; biindole nitrile double carbon hydrogen activation cyclization palladium.

A palladium-catalyzed synthesis of indole fused α-carbolines (pyridodiindoles) from 2,3′-biindoles and nitriles has been developed. This conversion involves the double C-H activation and cyclization of 2,3′-biindoles with nitriles via C-C and C-N bond formation in a single step. However, C-3 cyanated biindoles were formed through a retro-Mannich pathway when the reaction was carried out with Et cyanoacetate.

Tetrahedron Letters published new progress about C-H bond activation. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, SDS of cas: 100-70-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Medjahed, Aboubakr published the artcileProcessability and mechanical properties of surface-modified glass-fibres/phthalonitrile composite and Al-Li alloy fibre-metal-laminates, Formula: C8H4N2, the main research area is glass fiber phthalonitrile aluminum lithium alloy mech property; glass phthalonitrile fiber metal laminate aluminum lithium alloy.

In this study, newly developed fiber-metal laminates (Al-LiFMLs) were prepared by a lay-up process of a high-performance surface-modified glass fibers/phthalonitrile (GFs/PN) composite and Al-Li alloy. The results showed that varying the composite considerably affected the tensile properties of the Al-LiFMLs, as well as exhibiting enhancements over the properties of both the individual Al-Li alloys and GFs/PN composite constituents. For instance, when the number of composite layers varied from 6 to 14, the ultimate tensile strength of the Al-LiFMLs increased from 315 to 611 MPa. It was revealed that the failure mode displayed a more ductile behavior (up to 20%) for all the developed Al-LiFMLs affected by the ductile fracture mode of the Al-Li alloy.

Materials Science and Technology published new progress about Elongation at break. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Formula: C8H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Guerriero, Antonella published the artcileSynthesis of New Ruthenium-CAP Complexes and Use as Catalysts for Benzonitrile Hydration to Benzamide, Safety of Picolinonitrile, the main research area is ruthenium triazaphosphatricyclotridecane complex preparation hydration catalyst.

The new bimetallic [Ru2(μ-Cl)3(CAP)6]Cl (1) and monometallic cis,cis,trans-[RuCl2(dmso-S)2(CAP)2] (2) complexes, bearing the water soluble cage-like phosphine CAP (1,4,7-triaza-9-phosphatricyclo[5.3.2.1]tridecane), were synthesized and characterized in solution by NMR spectroscopy and ESI-MS spectrometry. The complexes, endowed with high solubility and stability in water, were applied as catalysts for the proof-of-concept hydration of benzonitrile to benzamide in neat water at 100°C, achieving high conversions with only 1 mol % of catalyst, both in single runs and in catalyst recycling experiments

European Journal of Inorganic Chemistry published new progress about Hydration catalysts. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Safety of Picolinonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Mapukata, Sivuyisiwe published the artcileThe photocatalytic properties of zinc phthalocyanines supported on hematite nanofibers for use against methyl orange and Staphylococcus aureus, Computed Properties of 91-15-6, the main research area is photocatalytic property zinc phthalocyanin hematite nanofiber methyl orange; Staphylococcus aureus.

Heterogeneous photocatalysis is a promising approach for environmental remediation from contaminants including microorganisms and organic pollutants. In this work, hematite nanofibers are fabricated and modified with a novel monosubstituted Pc (4) as well as an asym. tetrasubstituted Pc (5) with the aim of creating hybrid photocataysts. The photocatalytic activities of the unmodified and phthalocyanine modified hematite nanofibers were compared based on their efficiencies in the photoinactivation of S. aureus and photooxidation of methyl orange. For both applications, the hybrid nanofibers were found to be more efficient photocatalysts than the unmodified hematite nanofibers. Comparison of the modified nanofibers (4-Fe2O3 and 5-Fe2O3) showed that they have comparable antibacterial activity while the 5-Fe2O3 nanofibers are the best for the photooxidation of methyl orange. The singlet oxygen generation efficiency, high activity, versatility, regenerability and thus reusability of the fabricated hybrid nanofibers makes them ideal candidates for real life water treatment studies.

Journal of Photochemistry and Photobiology, A: Chemistry published new progress about Absorption spectra. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Computed Properties of 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Gao, Jing published the artcileTheoretical search of a simple characteristic for long-lived organic room-temperature phosphorescence materials with H aggregation, Safety of Phthalonitrile, the main research area is thioxanthone derivative hydrogen aggregation room temperature phosphorescence.

Recently, more and more room temperature phosphorescent (RTP) phenomena have been observed in crystals and organic aggregates, which indicates the dependence of RTP luminescence properties on the mol. packing patterns. At present, an important kind of reported RTP material are those possessing H-aggregation, which is considered to suppress fluorescence and improve the lifetime of excited triplet states. Herein, we tried to find a simple characteristic for H-aggregated RTP materials through exploring the processes of electron transition and energy transfer of the dimers in H-aggregation. An interesting phenomenon aroused our interest, i.e., the overlapping area between H-aggregated dimers exhibits strong correlation with the phys. parameters characterizing the RTP performance, such as the number of ISC channels, the spin-orbital coupling (SOC) value, the oscillator strengths of singlet states, the energy transfer rate between the triplet states, and the final RTP lifetime. The scanning of the intermol. relative position shows that an overlapping area within 40-60% could prolong the phosphorescence lifetime, which could be further proved by other H-aggregated crystals. This exploration not only highlights the important role of the overlapping area in characterizing the phosphorescence lifetime, but also provides guidance for developing persistent pure organic RTP materials.

Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published new progress about Absorption spectra. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Safety of Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Leijendekker, Leonardus H. published the artcileDevelopment, Scope, and Applications of Titanium(III)-Catalyzed Cyclizations to Aminated N-Heterocycles, Synthetic Route of 1885-29-6, the main research area is aminoindole aminopyrrole preparation fluorescence; imine cyclization titanium catalyzed; homogeneous catalysis; nitrogen heterocycles; reduction; titanium; umpolung.

The exceptionally mild conditions of a titanium(III)-catalyzed cyclization reaction paired with a convenient acid/base extraction was enabled the straightforward synthesis, isolation, and direct N-functionalization of amino heterocycles such as 3-aminoindoles I [R = Ph, 2-thienyl, 1-naphthyl, etc.] and -pyrroles. The unprotected heterocycles were ideal building blocks for the installation of aminated indoles and pyrroles into target mols., but their sensitivity had previously impeded their synthesis by modern catalytic methods. This full paper presented the development and extended scope of the new cyclization methodol. The transformation of the products into fused bis-indoles was also demonstrated along with the discovery of an unusual palladium-catalyzed reductive biphenyl coupling reaction. The titanium(III)-catalyzed cyclization had also been applied to the synthesis of substituted 3-iminoindolines, which were of potential interest for applications in natural product synthesis and exhibit tunable blue-to-green fluorescence properties.

Chemistry – A European Journal published new progress about Absorption spectra. 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Synthetic Route of 1885-29-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Meerovich, G. A. published the artcileNovel Polycationic Photosensitizers for Antibacterial Photodynamic Therapy, Name: Phthalonitrile, the main research area is polycationic photosensitizer antibacterial photodynamic therapy; Aggregation; Antibacterial photodynamic therapy; cationic photosensitizer; Bacterial biofilms; Bacteriochlorins; Luminescence.

Antibacterial photodynamic therapy (APDT) is a promising method of treating local infected foci, in particular, surgical and burn wounds, trophic and diabetic ulcers. Photodynamic inactivation (PDI) is able to effectively destroy bacterial cells without them developing resistance in response to treatment. This work was dedicated to the study of photophys. and antibacterial properties of new photosensitizers (PS) based on polycationic phthalocyanines and synthetic bacteriochlorins for photodynamic inactivation of P. aeruginosa bacteria and their biofilms. Gram-neg. bacteria P. aeruginosa are often found in infected wounds, presumably in biofilm state and are characterized by rather low susceptibility to APDT, which is a problem. PS were studied for possible aggregation at various concentrations by means of absorption and fluorescence spectroscopy. The results of studies of the ZnPcChol8, (3-PyHp)4BCBr4 and (3-PyEBr)4BCBr4 in water and serum confirm the assumption of a low degree of their aggregation at high concentrations Consequently, their photodynamic efficiency is high enabling to use these PS at high concentrations to sensitize pathol. foci for APDT. It was shown that all the investigated PS had a high efficiency of photodynamic inactivation of Gram-neg. bacteria P. aeruginosa, as well as their biofilms. Tetracationic hydrophilic near-IR photosensitizer (3-PyEBr)4BCBr4 with reduced mol. size had significantly higher efficacy of photodynamic inactivation of P. aeruginosa biofilms compared with other studied photosensitizers.

Advances in Experimental Medicine and Biology published new progress about Absorption spectra. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Name: Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts