Tag: M.W=100-150

Wang, Shichun published the artcileSynthesis and reactivity of the uranium phosphinidene metallocene [η5-1,3-(Me3Si)2C5H3]2U(:P-2,4,6-iPr3C6H2)(OPMe3): influence of the coordinated Lewis base, Product Details of C8H4N2, the main research area is reactivity uranium phosphinidene metallocene Lewis base; isothiocyanate aldehyde nitrile isonitrile azide reactivity uranium phosphinidene metallocene.

This paper describes the synthesis and reactivity of [η5-1,3-(Me3Si)2C5H3]2U(:P-2,4,6-iPr3C6H2)(OPMe3) (6) which is accessible from a ligand exchange reaction between [η5-1,3-(Me3Si)2C5H3]2U(:P-2,4,6-iPr3C6H2)(OPPh3) (2) and Me3PO at ambient temperature Phosphinidene 6 exhibits no reactivity towards internal alkynes, but readily reacts with various hetero-unsaturated mols. such as isothiocyanates, aldehydes, nitriles, isonitriles, and organic azides, forming uranium sulfido, oxido, imido, and uranaheterocyclic compounds Nevertheless, with the bidentate ortho-dicyanobenzene o-C6H4(CN)2 the zwitterionic species [η5-1,3-(Me3Si)2C5H3]2U[NHC(N){C6H4CP(2,4,6-iPr3C6H2)CH2PMe2O}] (13) is isolated in good yield. Moreover, 6 converts with Ph2S2 to the uranium(III) phenylthiolate compound [η5-1,3-(Me3Si)2C5H3]2USPh(OPMe3) (7) in good isolated yield. Furthermore, the influence of the Lewis base on the reactivity of the uranium phosphinidene metallocenes has also been evaluated.

Dalton Transactions published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Product Details of C8H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Paternoga, Jan published the artcileHantzsch Ester-Mediated Photochemical Transformations in the Ketone Series: Remote C(sp3)-H Arylation and Cyclopentene Synthesis through Strain Release, Related Products of nitriles-buliding-blocks, the main research area is ketocyclopropane preparation terminalalkyne diastereoselective cycloaddition Hantzsch ester green chem; mesyloxyketone terminal alkyne diastereoselective cycloaddition Hantzsch ester green chem; ketocyclopentene preparation; cyanopyridine ketocyclopropane preparation coupling reaction Hantzsch ester green chem; cyano pyridine mesyloxyketone coupling reaction Hantzsch ester green chem; pyridinylketone preparation.

A metal-free Hantzsch ester-mediated synthesis of cyclopentenylketones as well as γ-hetarylketones starting from ketocyclopropanes under eco-friendly conditions was developed. The versatility of the developed conditions was shown by reacting ketocyclopropanes in both a formal [3 + 2] cycloaddition with terminal alkynes (further investigated using theor. calculations) and a radical C-C-coupling with cyanopyridines. The newly developed methodologies were later on utilized as a downstream reaction for photogenerated cyclopropanes combining UV and visible light photochem. Following this procedure, a UV-driven Norrish-Yang-type reaction induced the ring strain of the intermediates, which served as activation energy for the subsequent ring transformation.

Journal of Organic Chemistry published new progress about Alkynes, α- Role: RCT (Reactant), RACT (Reactant or Reagent). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Related Products of nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Wang, Qiang published the artcileBase-Promoted Nitrile-Alkyne Domino-Type Cyclization: A General Method to Trisubstituted Imidazoles, Application In Synthesis of 100-70-9, the main research area is trisubstituted imidazole preparation; alkyne nitrile potassium tert butylate domino cyclization.

An efficient base promoted nitrile-alkyne domino-type cyclization for multicomponent assembly of imidazoles from alkynes, nitriles, and tBuOK has been developed, which could run even in the absence of solvent on a gram scale with complete atom economy. This method contributes directly to reaching the synthesis of valuable imidazole derivatives from readily available raw materials.

Organic Letters published new progress about Alkynes, α- Role: RCT (Reactant), RACT (Reactant or Reagent). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Application In Synthesis of 100-70-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Yan, Xinlong published the artcileAerobic oxidation of primary benzylic amines to amides and nitriles catalyzed by ruthenium carbonyl clusters carrying N,O-bidentate ligands, Formula: C6H4N2, the main research area is trinuclear ruthenium carbonyl catalyst preparation; nitrile preparation; amide preparation; benzylic amine aerobic oxidation.

Four trinuclear ruthenium carbonyl clusters were synthesized from the reactions of Ru3(CO)12 with the corresponding N,O-bidentate ligands (two pyridyl alcs. and two Schiff bases) resp. in a ratio of 1 : 2. Three new complexes were fully characterized by elemental anal., FT-IR, NMR and X-ray crystallog. The catalytic activity of these ruthenium complexes for the aerobic oxidation of primary benzylic amines to amides and nitriles in the presence of t-BuOK was investigated.

Dalton Transactions published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Formula: C6H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Thirukovela, Narasimha Swamy published the artcileActivation of nitriles by silver(I) N-heterocyclic carbenes: An efficient on-water synthesis of primary amides, Synthetic Route of 100-70-9, the main research area is silver NHC catalyst preparation; nitrile silver NHC catalyst hydration; primary amide preparation.

A first example of silver(I) N-heterocyclic carbene (Ag(I)-NHC) catalyzed on-water synthesis of primary amides by hydration of nitriles under mild reaction conditions was described. This organometallic catalytic system has excellent tolerance for various homo-aromatic, hetero-aromatic and aliphatic nitriles to afford primary amides in good yields in neat water.

Tetrahedron published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Synthetic Route of 100-70-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Vyas, Komal M. published the artcileArene-ruthenium(II)-phosphine complexes: Green catalysts for hydration of nitriles under mild conditions, Safety of Picolinonitrile, the main research area is ruthenium arene phosphine complex green catalyst nitrile hydration amide; crystal structure mol ruthenium arene phosphine complex preparation.

Three new arene-ruthenium(II) complexes were prepared by treating [{RuCl(μ-Cl)(η6-arene)}2] (η6-arene = p-cymene) dimer with tri(2-furyl)phosphine (PFu3) and 1,3,5-triaza-7-phosphaadamantane (PTA), resp. to obtain [RuCl2(η6-arene)PFu3] [Ru]-1, [RuCl(η6-arene)(PFu3)(PTA)]BF4 [Ru]-2 and [RuCl(η6-arene)(PFu3)2]BF4 [Ru]-3. All the complexes were structurally identified using anal. and spectroscopic methods including single-crystal X-ray studies. The effectiveness of resulting complexes as potential homogeneous catalysts for selective hydration of different nitriles into corresponding amides in aqueous medium and air atm. was explored. There was a remarkable difference in catalytic activity of the catalysts depending on the nature and number of phosphorus-donor ligands and sites available for catalysis. Exptl. studies performed using structural analogs of efficient catalyst concluded a structural-activity relationship for the higher catalytic activity of [Ru]-1, being able to convert huge variety of aromatic, heteroaromatic and aliphatic nitriles. The use of eco-friendly water as a solvent, open atm. and avoidance of any organic solvent during the catalytic reactions prove the reported process to be truly green and sustainable.

Inorganic Chemistry Communications published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Safety of Picolinonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Vyas, Komal M. published the artcileArene-ruthenium(II)-phosphine complexes: Green catalysts for hydration of nitriles under mild conditions, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks), the main research area is ruthenium arene phosphine complex green catalyst nitrile hydration amide; crystal structure mol ruthenium arene phosphine complex preparation.

Three new arene-ruthenium(II) complexes were prepared by treating [{RuCl(μ-Cl)(η6-arene)}2] (η6-arene = p-cymene) dimer with tri(2-furyl)phosphine (PFu3) and 1,3,5-triaza-7-phosphaadamantane (PTA), resp. to obtain [RuCl2(η6-arene)PFu3] [Ru]-1, [RuCl(η6-arene)(PFu3)(PTA)]BF4 [Ru]-2 and [RuCl(η6-arene)(PFu3)2]BF4 [Ru]-3. All the complexes were structurally identified using anal. and spectroscopic methods including single-crystal X-ray studies. The effectiveness of resulting complexes as potential homogeneous catalysts for selective hydration of different nitriles into corresponding amides in aqueous medium and air atm. was explored. There was a remarkable difference in catalytic activity of the catalysts depending on the nature and number of phosphorus-donor ligands and sites available for catalysis. Exptl. studies performed using structural analogs of efficient catalyst concluded a structural-activity relationship for the higher catalytic activity of [Ru]-1, being able to convert huge variety of aromatic, heteroaromatic and aliphatic nitriles. The use of eco-friendly water as a solvent, open atm. and avoidance of any organic solvent during the catalytic reactions prove the reported process to be truly green and sustainable.

Inorganic Chemistry Communications published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Czegeni, Csilla Eniko published the artcileSelective hydration of nitriles to corresponding amides in air with Rh(I)-N-heterocyclic complex catalysts, Synthetic Route of 100-70-9, the main research area is rhodium heterocyclic complex catalyst nitrile hydration crystal structure.

A new synthetic method for obtaining [RhCl(cod)(NHC)] complexes (1-4) (cod = η4 -1,5- cyclooctadiene, NHC = N-heterocyclic carbene: IMes, SIMes, IPr, and SIPr, resp.) is reported together with the catalytic properties of 1-4 in nitrile hydration. In addition to the characterization of 1-4 in solution by 13C NMR spectroscopy, the structures of complexes 3, and 4 have been established also in the solid state with single-crystal X-ray diffraction anal. The Rh(I)-NHC complexes displayed excellent catalytic activity in hydration of aromatic nitriles (up to TOF = 276 h-1) in water/2-propanol (1/1 volume/volume) mixtures in air.

Catalysts published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Synthetic Route of 100-70-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Wu, Mei published the artcileDIPEA-induced activation of OH- for the synthesis of amides via photocatalysis, Formula: C7H6N2, the main research area is nitrile eosin Y photocatalyst diisopropylethylamine hydration; amide preparation green chem.

Herein, an efficient light-mediated strategy for the synthesis of amides in which a weak organic base acts as a reductant to induce the formation of OH- from water under metal-free conditions was reported. A mechanistic study revealed that the generation of an N,N-diisopropylethylamine (DIPEA) radical via single electron transfer (SET), with the assistance of photocatalyst, that increased the nucleophilicity of the water mols. with respect to the cyanides was essential. Moreover, the removal rate of nitrile in wastewater can be as high as 83%, indicating that this strategy had excellent potential for nitrile degradation

RSC Advances published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Formula: C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Guo, Beibei published the artcileHydration of nitriles using a metal-ligand cooperative ruthenium pincer catalyst, Formula: C6H4N2, the main research area is nitrile water ruthenium pincer catalyst hydration; amide preparation.

The catalytic nitrile hydration using ruthenium catalysts based on a pincer scaffold with a dearomatized pyridine backbone. These complexes catalyzed the nucleophilic addition of H2O to a wide variety of aliphatic and (hetero)aromatic nitriles in tBuOH as solvent. Reactions occurred under mild conditions (room temperature) in the absence of additives. A mechanism for nitrile hydration was proposed that is initiated by metal-ligand cooperative binding of the nitrile.

Chemical Science published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Formula: C6H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts