Tag: M.W=100-150

Zhao, Yanbin published the artcileVanadium-catalyzed Oxidative Conversion of Primary Aromatic Alcohols into Amides and Nitriles with Molecular Oxygen, Quality Control of 100-70-9, the main research area is amide preparation green chem; nitrile preparation green chem; aldehyde preparation green chem; acid preparation green chem; primary alc ammoxidation vanadium catalyst; Alcohol; Amide; Catalytic oxidation; Nitrile; Vanadium.

Herein, a vanadium-based material V-N-C-700 was prepared via a simple and convenient method, and employed for liquid-phase catalytic ammoxidation of alcs. RCH2OH (R = n-Bu, Ph, pyridin-2-yl, etc.) with mol. oxygen. By using V-N-C-700/2-picolinic acid, primary aromatic alcs. were smoothly converted into the amides RC(O)NH2 and nitriles RCN in the presence of urea. The corresponding aldehydes RCHO are the key intermediates, and 2-picolinic acid could significantly enhance oxidation of alcs. into aldehydes. The amides were formed simultaneously along with nitriles, rather than only from nitriles via successive hydration. This work further expands non-noble metal catalysts for the preparation of amides and nitriles.

Chemistry – An Asian Journal published new progress about Aldehydes Role: SPN (Synthetic Preparation), PREP (Preparation). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Quality Control of 100-70-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Sheng, Hui-Yang published the artcileCopper-catalyzed Tandem Cyclization to Access 4-Aminoquinoline Derivatives, Name: 2-Aminobenzonitrile(Flakes or Chunks), the main research area is nitroethenylaryl aminobenzonitrile copper catalyst tandem Michael heterocyclization oxidation; nitro arylquinolinamine preparation.

An efficient and practical method for the synthesis of 4-aminoquinoline derivativeswas developed via copper-catalyzed cascade cyclization of 2-aminobenzonitrile and nitroolefins. This reaction proceeded through a consecutive Michael addition/cyclization/oxidization protocol, providing 4-aminoquinolines with moderate to excellent yields under mild conditions. This method features readily available materials, one-pot one-step operation, and proceeded without bases.

Chemistry Letters published new progress about Alkenes, nitro Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Name: 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kim, Jihyeon published the artcileCopper(II)-Catalyzed Aerobic Oxidation of Amines: Divergent Reaction Pathways by Solvent Control to Imines and Nitriles, HPLC of Formula: 1885-29-6, the main research area is aryl nitrile preparation; benzylamine aerobic oxidation copper catalyst; imine diastereoselective preparation; amine oxidative coupling copper catalyst.

The Cu(OAc)2-catalyzed aerobic oxidations of amines to imines RR1CH=NR2 [R = H, Me; R1 = Ph, 4-MeC6H4, 2-thienyl, etc.; R2 = cyclohexyl, Ph, Bn, etc.] and nitriles R3CN [R3 = n-heptyl, Ph, 2-thienyl, etc.] were identified under solvent control conditions and in the presence of mol. oxygen. By modulating the aerobic oxidation pathways of Cu(OAc)2 catalyst in different reaction solvents, the selective formations of homo-coupled imines, cross-coupled imines and nitriles were achieved from amine derivatives

Asian Journal of Organic Chemistry published new progress about Aralkyl amines Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, HPLC of Formula: 1885-29-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Gurjar, Jitendra published the artcileSulfuryl Fluoride Mediated Conversion of Aldehydes to Nitriles, Category: nitriles-buliding-blocks, the main research area is nitrile polyfunctional probe preparation sulfuryl fluoride; bioorthogonal chemistry; main group elements; nitriles; polyfunctional probes; synthetic methods.

Aliphatic, aromatic, and heteroaromatic aldehydes were readily converted to corresponding nitriles in a one-pot reaction sequence with hydroxylamine and sulfuryl fluoride. The reaction proceeds at room temperature, does not require metal catalysts and special precautions, and produces nitriles in excellent yields. It is compatible with a variety of functional groups, can be performed in aqueous and organic solvents, and is readily scalable to multigram quantities. Mild conditions and high selectivity of the reaction enabled the construction of polyfunctional probes containing nitrile, alkyne, azide, and fluorosulfate groups for further orthogonal derivatization.

Chemistry – A European Journal published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Category: nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nikpassand, M. published the artcileNovel Route for the Synthesis of 2-Arylquinazolinones Using Magnetic Nanocomposite of Multiwalled Carbon Nanotube, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks), the main research area is quinazolinone preparation green chem; aryl aldehyde aminobenzonitrile multiwalled carbon nanotube catalyst multicomponent.

A series of 2-aryl-2,3-dihydroquinazolin-4(1H)-ones have been synthesized in excellent yields and short reaction time by one-pot reaction of 2-aminobenzonitrile, ammonium hydroxide, and substituted benzaldehydes or 3-aryl-1-phenyl-1H-pyrazole-4-carbaldehydes in the presence of magnetic multiwalled carbon nanotube (mMWCNT) nanocomposite as a recoverable catalyst at room temperature The proposed methodol. offers several advantages such as mild reaction conditions, green media, excellent yields, simple procedure, and reduced environmental impact. Moreover, the catalyst can be easily recovered using an external magnet and recycled for 5 runs without significant loss of its catalytic activity. The structure of most of the synthesized 2-aryl-2,3-dihydroquinazolin-4(1H)-ones was confirmed by 1H and 13C NMR and FTIR spectra and elemental analyses.

Russian Journal of Organic Chemistry published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Ghanbari, Zahra published the artcileDiastereoselective Synthesis of Some Spiroheterocycles Using Base Reusable Heterogeneous Achiral Nanocatalyst in Aqueous Media, Application In Synthesis of 91-15-6, the main research area is silica coat nickel ferrite support tetrazole preparation thermal stability; aryl aldehyde dione tetrazol catalyst Knoevenagel condensation green chem; spiropyrimidinequinazoline diastereoselective preparation.

This research was based on the synthesis of some new diastereoselective spiroheterocycles relying on the application of nanocatalysts designed from the functionalized magnetic nanoparticles with tetrazole. Also, the achievement of suitable product with stereopurity through base catalytic path. Water as a green solvent, NiFe2O4 magnetic nanoparticles as a separable and reusable catalyst and using simple and high efficiency method were some important advantages of this research.

ChemistrySelect published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Application In Synthesis of 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Dutta, Apurba published the artcileGemini basic ionic liquid as bi-functional catalyst for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones at room temperature, Safety of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is reusable butanediyl bisdodecylmorpholinium hydroxide preparation thermal stability; cyanoaniline carbonyl compound butanediyl bisdodecylmorpholinium hydroxide tandem condensation; dihydroquinazolinone preparation green chem.

A cascade synthesis of 2,3-dihydroquinazolin-4(1H)-ones was developed from 2-aminobenzonitriles and carbonyl analogs using Gemini basic ionic liquid as green catalyst cum solvent at room temperature Both aldehydes and ketones were condensed with 2-aminobenzonitriles affording good to excellent yields of products. Moreover, the ionic liquids was reused up to 5th cycle without significant loss of catalytic activity.

Tetrahedron Letters published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Safety of 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Mao, Jianyou published the artcileSynthesis of Indoles through Domino Reactions of 2-Fluorotoluenes and Nitriles, Related Products of nitriles-buliding-blocks, the main research area is fluorotoluene nitrile tandem nucleophilic aromatic substitution heterocyclization; indole preparation; 2-fluorotoluenes; domino reactions; indoles; nitrogen heterocycles.

A straightforward, practical, and transition-metal-free assembly of 2-aryl indoles was reported. Simply combining readily available 2-fluorotoluenes, nitriles, LiN(SiMe3)2, and CsF enabled the generation of a diverse array of indoles (38 examples, 48-92 % yield). A range of substituents can be introduced into each position of the indole backbone (C4 to C7, and aryl groups at C2), providing handles for further elaboration.

Angewandte Chemie, International Edition published new progress about Aryl fluorides Role: RCT (Reactant), RACT (Reactant or Reagent). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Related Products of nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Chen, Zhen-Yu published the artcilePerfluorobutyl Iodide Mediated [1,2] and [2,3] Stevens Rearrangement for the Synthesis of Indolin-3-ones, Formula: C7H6N2, the main research area is indolinone preparation; tertiary aminoaryl ketone Stevens rearrangement perfluorobutyl iodide mediated.

The tertiary amine and ketone components of 1-carbonyl-substituted anilines underwent [1,2] and [2,3] Stevens rearrangement reactions, triggered by a C4F9 radical, formed from electron donor-acceptor complexes. This approach enabled the formation of a quaternary ammonium salt and thus a Stevens rearrangement to afford indolin-3-ones such as I [R1 = Me, Et, i-Pr; R2 = Bn, CH2CH=CH2, C(Me)=C=CH2, etc.; R3 = Me, Bn] and II [R4 = H, Cl, Br; R5 = H, MeO, Cl; R6 = H, MeO] under mild conditions.

Advanced Synthesis & Catalysis published new progress about Indolines Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Formula: C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Cao, Zhenyu published the artcileSynthesis of 2-pyridyl oxazoline esters and their organocatalytic application to the enantioselective silane reduction of ketones, Category: nitriles-buliding-blocks, the main research area is pyridyl oxazoline ester chiral preparation organocatalyst; chiral alc preparation enantioselective; ketone reduction organocatalyst.

The synthesis of a number of novel chiral 2-pyridyl oxazoline esters I (R = Me, (2R)-2-methylbutanoyl, (pyridin-2-yl)carbonyl, (naphthalen-1-yl)carbonyl, etc.) is reported along with the use of these in the enantioselective organocatalytic reduction of ketones 4-R1C6H4C(O)CH3 (R1 = H, methyl). The chiral alcs. 4-R1C6H4CH(OH)CH3 were prepared in good to excellent yields (up to 99%) and found to catalyze the reduction reactions with good conversions (up to 99%) and in moderate to good enantioselectivities (up to 65% at high conversion and 70% with lower reactivity). The results give an insight into the effects of the catalyst structure on the selectivity observed in the reaction.

ARKIVOC (Gainesville, FL, United States) published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Category: nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts