Tag: M.W=100-150

Sharma, Abhilash published the artcileA palladium-catalyzed cascade process for spirooxindole: an alternative way for the synthesis of spiro(indoline-3,2′-quinazolin)-2-ones, Product Details of C7H6N2, the main research area is spiroindolinequinazolinone preparation one pot palladium catalyst; aminobenzonitrile arylboronic acid isatin three component reaction.

A palladium-catalyzed cascade strategy has been developed for one-pot synthesis of functionalized spiro(indoline-3,2′-quinazolin)-2-one derivatives I (R = H, Me; R1 = H, 3-Me, 4-OMe, etc.; R2 = H, Me, F, etc.; R3 = H, Me, Ph, Bn) from readily available starting materials. The reaction proceeds via C-C and two C-N bond formations in a single reaction operation. This method offers an attractive pathway for the synthesis of a broad range of spiro(indoline-3,2′-quinazolin)-2-ones in good yields.

Organic & Biomolecular Chemistry published new progress about Aromatic nitriles Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Product Details of C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Ping, Ran published the artcileCatalytic Conversion of CO2 from Simulated Flue Gases with Aminophenol-Based Protic Ionic Liquids to Produce Quinazoline-2,4(1H,3H)-diones under Mild Conditions, Synthetic Route of 1885-29-6, the main research area is quinazolinedione synthesis carbon dioxide flue gas aminophenol ionic liquid.

Novel aminophenol-based protic ionic liquids (APILs) were designed and synthesized via one-step neutralization, and they were used as catalysts for conversion of 2-aminobenzonitriles and CO2 from simulated flue gases to produce quinazoline-2,4(1H,3H)-diones under mild conditions. The effects of anion-cation structures of APILs, various solvents, reaction parameters, and water contents on the product yields were investigated in detail. The catalyst recyclability and general applicability to different substrates were examined It showed that both the basicity of the reaction media and the synergistic activation of zwitterions to reactants played important roles during the catalysis. The optimum [HTMG][m-AP] catalyst cooperating with the DMF (DMF) solvent could selectively convert CO2 into various quinazoline-2,4(1H,3H)-diones with good to excellent product yields at 60°C and in a 0.1 MPa simulated flue gas atm. In addition, [HTMG][m-AP]/DMF was easily recycled and could be reused in up to five consecutive cycles without an obvious loss of activity. By comparison with the reported catalysts, [HTMG][m-AP]/DMF here showed a superior catalytic performance and a great potential for development. Finally, the activation behaviors of [HTMG][m-AP]/DMF to reactants were studied, and a synergistic catalytic mechanism was proposed.

ACS Sustainable Chemistry & Engineering published new progress about Aromatic nitriles Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Synthetic Route of 1885-29-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Miao, Meng published the artcileVisible-light-mediated external-reductant-free reductive cross coupling of benzylammonium salts with (hetero)aryl nitriles, Product Details of C8H4N2, the main research area is diarylmethane preparation; benzylammonium salt aryl nitrile photocatalyst cross coupling.

A novel visible-light-mediated external reductant-free reductive cross coupling for the construction of C sp2-C sp3 bonds was reported. A variety of benzylammonium salts RCH(R1)N+(CH3)3O-S(O)2CF3 (R = naphthalen-2-yl, 1-benzothiophen-3-yl, 4-tert-butylphenyl, etc.; R1 = H, Me, n-Pr) and 1,2,3,4-tetrahydro-N,N,N-trimethyl-1-naphthalenaminium 1,1,1-trifluoromethanesulfonate underwent selective coupling with (hetero)aryl nitriles R2CN (R2 = 4-cyano-3-methylphenyl, 2-phenylpyridin-4-yl, isoquinolin-1-yl, etc.) to deliver important diarylmethanes RCH(R1)R2 and 4-(1,2,3,4-tetrahydronaphthalen-1-yl)benzonitrile under mild reaction conditions. Importantly, photocatalysts can be omitted for many cases, which might involve the electron donor acceptor (EDA) complex. Mechanistic studies indicated that benzylic radicals might be involved as the key intermediates. Moreover, the in situ NMe3 generated via cleavage of C-N bond in ammonium salts acts as the electron donor, thus avoiding the use of external-reductant.

Science China: Chemistry published new progress about Aromatic nitriles Role: RCT (Reactant), RACT (Reactant or Reagent). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Product Details of C8H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Liu, Qixing published the artcileCopper-Catalyzed One-Pot Synthesis of 2,3-Dihydroquinazolin-4(1 H )-ones from 2-Nitrobenzonitriles and Carbonyl Compounds Mediated by Diboronic Acid in Methanol-Water, Synthetic Route of 1885-29-6, the main research area is dihydroquinazolinone preparation nitrobenzonitrile carbonyl Pinner Dimroth rearrangement.

A copper-catalyzed one-pot synthesis of 2,3-dihydroquinazolin-4(1 H)-ones with diboronic acid as a reductant in an aqueous medium is described. Various 2,3-dihydroquinazolin-4(1 H)-ones were prepared with good functional-group tolerance in good yields under mild conditions from readily available 2-nitrobenzonitriles and various carbonyl compounds

Synlett published new progress about Aromatic nitriles Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Synthetic Route of 1885-29-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Zeynizadeh, Behzad published the artcileA hassle-free and cost-effective transfer hydrogenation strategy for the chemoselective reduction of arylnitriles to primary amines through in situ-generated nickel (II) dihydride intermediate in water, Name: Phthalonitrile, the main research area is benzonitrile reduction chemoseslective green chem; benzyl amine preparation.

A new, simple, efficient, inexpensive, and chemoselective transfer hydrogenation strategy was introduced for the straightforward reduction of arylnitriles to corresponding primary amines using sodium borohydride (NaBH4) and nickel acetate tetrahydrate (Ni(OAc)2â€?H2O) through in situ-generated nickel (II) dihydride intermediate in the water medium at 50°. The presented methodol. featured moderate reaction conditions, nickel boride (Ni2B)-free trajectory, good-to-excellent yields of the products, relatively short reaction times, satisfactory chemoselectivity, and did not involve the use of toxic organic solvent and also any base or ligand.

Journal of Molecular Structure published new progress about Aromatic amides Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Name: Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Hazarika, Shikharani published the artcileSilica supported spinel structured cobalt ferrite multifunctional nanocatalyst for hydration of nitriles and oxidative decarboxylation of phenylacetic acids, Application In Synthesis of 1885-29-6, the main research area is aryl aldehyde preparation green chem; phenyl acetic acid oxidative decarboxylation silica support ferrite nanocatalyst; amide preparation green chem; nitrile hydration silica support cobalt ferrite nanocatalyst.

The silica-supported cobalt ferrite spinel nanocatalyst has been successfully synthesized by the coprecipitation method and extensively characterized by FTIR, XRD, SEM-EDX, TEM, BET, VSM, XPS, TGA, and ICP-AES anal. The bands observed at 3435 cm-1 (μOH of Si-OH) and 1637 cm-1 (γOH of Si-OH) in the FTIR spectrum of the as-synthesized nanocatalyst unambiguously tell the presence of silica support. Moreover, a very weak intensity and a medium intensity peak at 683 cm-1 and 463 cm-1 suggested intrinsic stretching vibrations of Fe-O and Co-O of cobalt ferrite, resp. The XRD pattern confirms the formation of CoFe2O4 spinel. The average crystallite size was found to be 5.4 nm as calculated by using the Debye-Scherrer equation based on the (220) plane while the average particle size was found to be 5.08 nm from TEM anal. The crystalline nature of the nanocomposite was confirmed by the SAED pattern. The successful incorporation of CoFe2O4 on the surface of silica was established by the BET surface area measurements. The silica-supported cobalt ferrite nanocatalyst has been explored as a heterogeneous multifunctional catalyst for hydration of nitriles RCN (R = Ph, pyridin-3-yl, 4-cyanobutyl, etc.) and oxidative decarboxylation of phenylacetic acids R1CH2C(O)OH (R1 = Ph, 2-hydroxynaphthalen-1-yl, 2,5-dimethoxyphenyl, etc.) as well under mild reaction conditions with moderate to excellent isolated yield of the desired products (60-99%). The catalyst was magnetically recoverable within a time frame of ~90 s and reusable up to the fifth catalytic cycle without profound loss of activity. A magnetic hysteresis study was performed to elucidate the magnetic behavior of the catalyst. The saturation magnetization value of 39.785 emu/g with a coercivity value of 110.87 Oe and saturation remanence value of 5.185 emu/g clearly indicated the presence of a ferromagnetic component in the material.

Applied Organometallic Chemistry published new progress about Aromatic amides Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Application In Synthesis of 1885-29-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Du, Jialei published the artcileCommercially Available CuO Catalyzed Hydrogenation of Nitroarenes Using Ammonia Borane as a Hydrogen Source, Product Details of C7H6N2, the main research area is nitroarene ammonia borane copper oxide catalyst hydrogenation; arylamine preparation.

The com. available CuO powder was demonstrated as robust catalyst for hydrogenation of nitroarenes using ammonia borane as a hydrogen source under mild conditions. Numerous amines (even sterically hindered, halogenated, and diamines) were obtained through this method. This monometallic catalyst is characteristic of support-free, excellent chemoselectivity, low-cost, and high recyclability, which will favor its future utilization in preparative reduction chem. Mechanistic studies were also carried out to clarify that diazene and azoxybenzene are key intermediates of this heterogeneous reduction

ChemCatChem published new progress about Aromatic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Product Details of C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Shuai, Qi published the artcileMetal-free chemoselective reduction of nitroaromatics to anilines via hydrogen transfer strategy, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks), the main research area is aromatic amine preparation chemoselective green chem; nitro aromatic reduction.

A novel protocol for chemoselective reduction of aromatic nitro compounds ArNO2 (Ar = Ph, 1,3-benzothiazol-6-yl, quinolin-8-yl, 4-NCC6H4, etc.) to aromatic amines ArNH2 has been established. The metal-free reduction goes through a hydrogen transfer process. Various easily reducible functional groups can be well tolerated under the optimized reaction conditions.

Chemical Papers published new progress about Aromatic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Goksu, Haydar published the artcileA Novel Hydrogenation of Nitroarene Compounds with Multi Wall Carbon Nanotube Supported Palladium/Copper Nanoparticles (PdCu@MWCNT NPs) in Aqueous Medium, Safety of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is multi wall carbon nanotube supported palladium copper nanocatalyst; aryl amine preparation; nitroarene hydrogenation palladium copper nanocatalyst.

A novel nanocatalyst, multi-wall carbon nanotube supported palladium/copper (PdCu@MWCNT) nanoparticles, was synthesized for the reduction of nitroarene compds to afford aryl amines ArNH2 [Ar = 4-MeC6H4, 3-HOC6H4, 1-naphthyl, etc.]. Characterization of the nanocatalyst was achieved by XRD, XPS, TEM, and Raman spectroscopy anal. In this study, the hydrogenation of nitroarenes to primary amine compounds was achieved in aqueous medium at room temperature The aniline derivatives were synthesized with high yields at mild conditions via novel PdCu@MWCNT nanocatalyst. The conversion of nitroarenes to amine derivatives was accomplished at 99% efficiency. In addition to its high activity, the PdCu@MWCNT catalyst was determined to be stable and reusable after the 3rd consecutive use for the reaction and provided 99% conversion of various compounds in the reduction reaction.

Scientific Reports published new progress about Aromatic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Safety of 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Moghaddam, Firouz Matloubi published the artcileAn advancement in the synthesis of nano Pd@magnetic amine-Functionalized UiO-66-NH2 catalyst for cyanation and O-arylation reactions, Related Products of nitriles-buliding-blocks, the main research area is palladium magnetic amine MOF UiO66 NH2 preparation thermal stability; benzonitrile preparation; phenyl aryl ether preparation.

The magnetic MOF-based catalytic system has been reported here to be an efficient catalyst for synthesis of benzonitriles and diarylethers of aryl halides under optimal conditions. The MOF catalyst was built based on magnetic nanoparticles and UiO-66-NH2 which further modified with 2,4,6-trichloro-1,3,5-triazine and 5-Ph tetrazole at the same time and the catalyst structure was confirmed by various techniques. This new modification has been applied to increase anchoring palladium into the support. Furthermore, the products’ yields were obtained in good to excellent for all reactions under mild conditions which result from superior activity of the synthesized heterogeneous catalyst containing palladium. Also, the magnetic property of the MOF-based catalyst makes it easy to sep. from reaction mediums and reuse in the next runs.

Scientific Reports published new progress about Aromatic ethers Role: SPN (Synthetic Preparation), PREP (Preparation). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Related Products of nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts