Tag: M.W=100-150

Schneekoenig, Jacob published the artcileCobalt pincer complexes for catalytic reduction of nitriles to primary amines, Safety of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is nitrile cobalt pincer complex catalyst reduction; alkylamine preparation.

Various cobalt pincer type complexes I [R = iPr, Cy, Ph; X = Cl, Br] and II [X = Cl, Br] were applied for the catalytic hydrogenation of nitriles to amines. Among these, catalyst I [R = Ph, X = Cl] was the most efficient, allowing the reduction of aromatic as well as aliphatic nitriles in moderate to excellent yields.

Catalysis Science & Technology published new progress about Aralkyl amines Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Safety of 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Xiong, Hao published the artcileThe Reaction of o-Aminoacetophenone N-Tosylhydrazone and CO2 toward 1,4-Dihydro-2H-3,1-benzoxazin-2-ones, Product Details of C7H6N2, the main research area is aminoacetophenone tosylhydrazone carbon dioxide fixation carbene insertion reaction; dihydrobenzoxazinone preparation.

A transition-metal-free reaction of o-aminoacetophenone N-tosylhydrazone and CO2 has been developed, leading to a series of 1,4-dihydro-2H-3,1-benzoxazin-2-ones in moderate to good yields. This procedure proceeds with the sequential fixation of CO2 by amino leading to carbamic acid and the intra- mol. insertion of hydroxyl to carbene.

Advanced Synthesis & Catalysis published new progress about Benzoxazinones Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Product Details of C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kong, Xianqiang published the artcileCyanation and cyanomethylation of trimethylammonium salts via electrochemical cleavage of C-N bonds, Product Details of C6H4N2, the main research area is trimethylammonium salt tosyl cyanide chemoselective electrocatalytic cyanation; nitrile preparation; azido methylbutenol trimethylammonium salt chemoselective electrocatalytic cyanomethylation; acetonitrile preparation.

A practical and mild electrochem. protocol for cyanation and cyanomethylation of trimethylammonium salts through a pathway involving C-N bond cleavage without the need for an external stoichiometric reducing agent or a sacrificial anode was developed. The reaction employed tosyl cyanide (TsCN) or azido allyl alc. as the cyanation or cyanomethylation reagent, resp. It showed high functional group compatibility and can be applied for the cyanation of natural product derivatives Preliminary mechanistic studies indicated the involvement of a radical addition pathway.

Organic Chemistry Frontiers published new progress about Acetonitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Product Details of C6H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nasrollahzadeh, Mahmoud published the artcilePd nanocatalyst adorning coral reef nanocomposite for the synthesis of nitriles: utility of Cucurbita pepo leaf extract as a stabilizing and reducing agent, Application In Synthesis of 91-15-6, the main research area is palladium nanocatalyst coralreef nanocomposite nitrile Cucurbita stabilizing reducing agent; Cucurbita pepo; Pd nanoparticles; Pd/coral reef nanocomposite; aryl halide; cyanation.

A simple procedure for the palladium-catalyzed cyanation of aryl halides is described via a nucleophilic non-toxic cyanide source, K4[Fe(CN)6] in the presence of Pd/coral reef nanocomposite as a heterogeneous catalyst; the protocol provides a useful and easy method for the synthesis of aryl nitriles that are generated from the corresponding variant aryl halides, with sodium carbonate as a base. The nanocatalyst was prepared by a biol. process using aqueous extract of leaves of Cucurbita pepo as a stabilizing and reducing agent and coral reef as a natural support, without deploying any hazardous chems. The catalyst, that is easily separable from the reaction mixture and reused multiple times, was characterized by FT-IR (Fourier-Transform IR Spectroscopy), ICP-AES (Inductively Coupled Plasma Atomic Emission Spectroscopy), XRD (X-ray Diffraction), TEM (Transmission Electron Microscopy), FE-SEM (Field Emission SEM), EDS (Energy Dispersive X-ray Spectroscopy) and elemental mapping.

Nanomaterials published new progress about Aromatic nitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Application In Synthesis of 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Liu, Si-Zhan published the artcileCopper-promoted cyanation of aryl iodides with N,N-dimethyl aminomalononitrile, Product Details of C6H4N2, the main research area is iodoarene dimethyl aminomalononitrile copper catalyst cyanation; aryl nitrile preparation.

A copper-promoted cyanation of aryl iodides was successfully developed by using N,N-di-Me aminomalononitrile as the cyanide source with moderate toxicity and better stability. The reaction featured broad substrate scope, excellent reaction yields, readily available catalyst, and simple reaction conditions.

Tetrahedron Letters published new progress about Aromatic nitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Product Details of C6H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Wang, Shengyu published the artcilePd@CeO2-catalyzed cyanation of aryl iodides with K4Fe(CN)6·3H2O under visible light irradiation, Category: nitriles-buliding-blocks, the main research area is aryl nitrile preparation green chem photochem; potassium ferricyanide aryl iodide cyanation palladium catalyst.

A new protocol based on the combination of the catalyst Pd@CeO2, nontoxic cyanide source K4Fe(CN)6·3H2O, and driving force visible light irradn was developed. The reaction is performed at relatively moderate temperature (55°C) and exhibits good catalytic efficiency of product aryl nitriles RCN (R = Ph, 2-nitrophenyl, thiophen-2-yl, etc.) (yields of 89.4%). Moreover, the catalyst Pd@CeO2 possesses good reusability with a slight loss of photocatalytic activity after five consecutive runs. The reaction system based on the above combination shows a wide range of functional group tolerance under the same conditions. Reaction conditions such as temperature, time, the component of catalyst, and solutions are optimized by studying cyanation of 1-iodo-4-nitrobenzene as model reaction. According to these results, the possible mechanism of Pd@CeO2-catalyzed cyanation of aryl iodides RI under visible light irradiation is proposed based on the influence of visible light on the catalyst and reactant compounds In all, an environmental and economic method for preparation of aryl nitriles from cyanation of aryl iodides based on the goal of green chem. for sustainable development was provided.

Applied Organometallic Chemistry published new progress about Aromatic nitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Category: nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Heydari, Somayyeh published the artcileAn overview on the progress and development on the palladium catalyzed direct cyanation, SDS of cas: 91-15-6, the main research area is aryl nitrile preparation; arylsulfonyl cyanamide phenylboronic acid cyanation palladium catalyst.

The simultaneous use of the new Pd nano-catalyst as well as the three types of the N-arylsulfonyl cyanamides 4-ClC6H4N(CN)S(O)2C6H4(4-X) (X = CH3, Br, NO2) as potent reagents for the in situ generation of the pos. CN ion for the direct cyanation of phenylboronic acids ArB(OH)2 [Ar = 4-ClC6H4, pyridin-3-yl, 2-(dihydroxyboranyl)phenyl, etc.] in acetonitrile at reflux conditions has been described.

Inorganica Chimica Acta published new progress about Aromatic nitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, SDS of cas: 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Fathalla, Walid published the artcileNovel domino synthesis of 2-(2,3,4-substituted phenyl)quinazolin-4-amine, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks), the main research area is phenyl quinazolin amine preparation; cyanophenyl benzimidoyl isothiocyanate isopropyl amine tandem reaction.

Convenient domino protocol was developed for the synthesis of 2-arylquinazolin-4-amines by the reaction of N-(2-cyanophenyl) substituted benzimidoyl isothiocyanates with iso-Pr amine. The major advantages of this protocol are short reaction times, mild conditions, simple work up, high yields, and pure products. The efficacy of this protocol owes to the competence of synthesis, pure isolation of imidoyl isothiocyanates, and the unique structure conformation of the corresponding intermediate thiourea derivatives

Journal of Heterocyclic Chemistry published new progress about Amines Role: RCT (Reactant), RGT (Reagent), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Tavakoli, Ghazal published the artcileThe reductive deaminative conversion of nitriles to alcohols using para-formaldehyde in aqueous solution, Related Products of nitriles-buliding-blocks, the main research area is benzylic alkyl primary alc chemoselective preparation; ruthenium catalyst chemoselective reduction nitrile paraformaldehyde water; mechanism reductive deamination nitrile paraformaldehyde water ruthenium catalyst.

In the presence of [Ru(p-cymene)Cl2]2, paraformaldehyde in H2O/toluene acted as a reductant for the chemoselective reductive deamination of alkyl and aryl nitriles to yield alkyl or benzylic primary alcs. The mechanism of the reaction is studied using the characterization of reaction intermediates by mass spectrometry; dimeric ruthenium complexes are necessary to generate reduced ruthenium complexes from paraformaldehyde, while nitrile coordination generates monomeric complexes of ruthenium which reduce the nitriles to alcs.

Catalysis Science & Technology published new progress about Aralkyl alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Related Products of nitriles-buliding-blocks.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Tavakoli, Ghazal published the artcileThe reductive deaminative conversion of nitriles to alcohols using para-formaldehyde in aqueous solution, COA of Formula: C8H4N2, the main research area is benzylic alkyl primary alc chemoselective preparation; ruthenium catalyst chemoselective reduction nitrile paraformaldehyde water; mechanism reductive deamination nitrile paraformaldehyde water ruthenium catalyst.

In the presence of [Ru(p-cymene)Cl2]2, paraformaldehyde in H2O/toluene acted as a reductant for the chemoselective reductive deamination of alkyl and aryl nitriles to yield alkyl or benzylic primary alcs. The mechanism of the reaction is studied using the characterization of reaction intermediates by mass spectrometry; dimeric ruthenium complexes are necessary to generate reduced ruthenium complexes from paraformaldehyde, while nitrile coordination generates monomeric complexes of ruthenium which reduce the nitriles to alcs.

Catalysis Science & Technology published new progress about Aralkyl alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, COA of Formula: C8H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts