Tag: M.W=100-150

Nitrile is any organic compound with a −C≡N functional group. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Application of C9H5N.

Zhang, Xitao;Zhang, Sheng;Li, Shihong;Feng, Xiujuan;Yamamoto, Yoshinori;Bao, Ming research published 《 Three-component addition of terminal alkynes, carboxylic acids, and tert-butyl hypochlorite》, the research content is summarized as follows. This paper described the unprecedented three-component addition of terminal alkynes, carboxylic acids, and tert-Bu hypochlorite. This new type of addition proceeds smoothly to produce gem-dichloroalkane derivatives in satisfactory to excellent yields via successive two-time additions under mild conditions. The synthetically useful functional groups, such as Cl, Br, CN, and NO₂, remained intact in the final products.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Application of C9H5N

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Recommanded Product: 4-Ethynylbenzonitrile.

Yang, Bin;Yang, Junfeng;Zhang, Junliang research published 《 Synthesis of Axially Chiral Anilides Enabled by a Palladium/ Ming-Phos-Catalyzed Desymmetric Sonogashira Reaction》, the research content is summarized as follows. Atropisomeric anilides are one of important C-N axially chiral compounds Compared with the N-terminal functionalization to prepare such compounds, C-terminal functionalization strategies have been rarely reported. Authors describe herein an efficient synthesis of axially chiral anilides enabled by Pd-catalyzed desym. Sonogashira cross-coupling reactions with the use of a newly identified Ming-Phos. Moderate to high yields with high enantioselectivities (up to 98% ee) were obtained.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Recommanded Product: 4-Ethynylbenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Product Details of C9H5N.

Wu, Jianglong;Wang, Chenyu;Wang, Zhongjie;Li, Hongjun;Liu, Ruyan;Wang, Yan;Zhou, Pengsheng;Li, Dianjun;Yang, Jinhui research published 《 Base/B₂pin₂-Mediated Iodofluoroalkylation of Alkynes and Alkenes》, the research content is summarized as follows. A base/B₂pin₂-mediated iodofluoroalkylation of alkynes and a part of alkenes, using Et difluoroiodoacetate (ICF₂CO₂Et) or IC_nF_2n+1(n = 3, 4, 6) as difluoroacetylating or perfluoroalkylating reagent, is disclosed. The reaction proceeds under mild conditions, and iododifluoroalkylation, hydrodifluoroalkylation and several perfluoroalkylation products were generated from alkynes or alkenes. Notably, this methodol. provides a simple access to difluoroalkylated and perfluoroalkylated organic compounds starting from simple alkynes or alkenes.

Product Details of C9H5N, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Safety of 4-Ethynylbenzonitrile.

Xu, Tianhao;Zhou, Xiangbing;Han, Yuhui;Zhang, Liangwei;Liu, Long;Huang, Tianzeng;Li, Chunya;Tang, Zhi;Wan, Shungang;Chen, Tieqiao research published 《 Palladium-catalyzed stereo-selective three-component cis-1,2-arylalkynylation of bicyclic alkenes with aryltriflates and terminal alkynes》, the research content is summarized as follows. Synthesis of (1S,2R,3S,4R)-2-(arylethynyl)-3-(aryl)bicyclo[2.2.1]heptanes I [R = Ph, 4-MeC₆H₄, 4-FC₆H₄, etc.; Ar = Ph, 2-MeC₆H₄, 4-MeOC₆H₄, etc.; R¹ = H, C(O)Me] via a palladium-catalyzed stereo-selective cis-1,2-arylalkynylation of bicyclic alkenes with aryl triflates and terminal alkynes was developed. This reaction showed high functional group tolerance and could be applied to the modification of bioactive mols. This three-component reaction provided a practical method for preparing the value-added bicyclo[2.2.1]heptanes derivatives

Safety of 4-Ethynylbenzonitrile, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. HPLC of Formula: 3032-92-6.

Wang, Qiuzhu;Wang, Mengning;Wu, Qianhui;Ma, Mengtao;Zhao, Binlin research published 《 Synthesis of β-Polychlorinated Alkynes Enabled by Copper-Catalyzed Multicomponent Reaction》, the research content is summarized as follows. Functional mols. bearing polychlorinated moieties usually play versatile roles in organic synthesis and biochem. A copper-catalyzed multicomponent polychloro-carboalkynylation of alkenes presents an efficient and operationally simple approach for the synthesis of β-polychlorinated alkynes. Mechanistic experiments were conducted demonstrating that an in situ generated copper acetylide complex was the real catalyst and reactive intermediate during the copper-catalytic cycle. And enantioselective exploration demonstrated potential application for the synthesis of chiral β-polychlorinated alkynes.

HPLC of Formula: 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Reference of 3032-92-6.

Wang, Xiaoshuang;Sun, Lei;Wang, Miaomiao;Maestri, Giovanni;Malacria, Max;Liu, Xiang;Wang, Yanlan;Wu, Lingang research published 《 C-I Selective Sonogashira and Heck Coupling Reactions Catalyzed by Aromatic Triangular Tri-palladium》, the research content is summarized as follows. Aromatic triangular tri-palladium cations, abbreviated as [Pd₃]⁺, have shown interesting photoelec. properties, Lewis basic character, and excellent activities in catalytic hydrogenation. Herein, authors report the highly efficient and C-I selective Sonogashira and Heck coupling reactions catalyzed by these tri-palladium complexes. Benefiting from the moderate C-I bond association energy, these tri-palladiums presented exclusive reactivities to aryl iodides over the brominated aromatics in coupling reactions. In the Sonogashira pathway, good to excellent isolated yields (71-95%) were achieved. Gram-scale reaction reached 93% of yield with palladium loading as few as 0.06 mol %. Authors also explored the electronic and steric effects for Ph alkynes and aryl iodides including heteroaromatics like thiophene, pyridine, pyrazole, and pyrazine. Similarly, yields of 71-96% were obtained for palladium loading of 1.5 mol% through catalyzed Heck coupling of aryl iodides and alkenes. The HRMS monitoring revealed that [Pd₃]⁺ maintained as whole entity during the catalytic process due to its robusness.

Reference of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Recommanded Product: 4-Ethynylbenzonitrile.

Wang, Xuemei;Zhou, Liang;Zhang, Hongkui;Ren, Xiaoyu;Gao, Guowei;Wang, Tianli research published 《 Enantioselective γ-Addition-Driven Cascade of β,γ-Unsaturated Ketones by Ion-Pair Catalysis: Access to Chiral 1,3-Dioxolochroman Scaffolds》, the research content is summarized as follows. A highly enantioselective γ-addition-driven cascade of β,γ-unsaturated carbonyl compounds by bifunctional ion-pair catalysis was developed. With this protocol, a range of functionalized chiral 1,3-dioxolochroman derivatives I [Ar¹ = Ph, 3-FC₆H₄, 2-naphthyl, etc.; Ar² = Ph, 4-MeOC₆H₄, 3-FC₆H₄, etc.; Ar³ = Ph, 2-ClC₆H₄, 4-MeOC₆H₄, etc.] were prepared in high yields with superior stereoselectivities (>99% ee and >20:1 dr). The utility of this method was demonstrated by one-pot synthesis, scaled-up preparation, and facile transformation. Moreover, mechanistic investigations provided insights into reaction pathway and origin of chiral induction.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Recommanded Product: 4-Ethynylbenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Recommanded Product: 4-Ethynylbenzonitrile.

Wang, Zhenyu;Cao, Chengyao Kimmy;Tretyakov, Evgeny;Liu, Wei;Chen, Chao research published 《 A Facile Stereoselective Bis-Trifluoromethylselenolation Reaction of Alkynes with AgSeCF₃ and N-Bromosuccinimide》, the research content is summarized as follows. A facile stereoselective bis-trifluoromethylselenolation reaction of alkyne derivatives was realized for the first time. The reaction of alkyne derivatives and AgSeCF₃ was found to proceed in the presence of N-bromosuccinimide and water in THF and afforded bis-trifluoromethylselenolated products in moderate-to-excellent yields. The new methodol. enables one-pot synthesis with a broad substrate range.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Recommanded Product: 4-Ethynylbenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. HPLC of Formula: 3032-92-6.

Wang, Qiuzhu;Wang, Mengning;Wu, Qianhui;Ma, Mengtao;Zhao, Binlin research published 《 Synthesis of β-Polychlorinated Alkynes Enabled by Copper-Catalyzed Multicomponent Reaction》, the research content is summarized as follows. Functional mols. bearing polychlorinated moieties usually play versatile roles in organic synthesis and biochem. A copper-catalyzed multicomponent polychloro-carboalkynylation of alkenes presents an efficient and operationally simple approach for the synthesis of β-polychlorinated alkynes. Mechanistic experiments were conducted demonstrating that an in situ generated copper acetylide complex was the real catalyst and reactive intermediate during the copper-catalytic cycle. And enantioselective exploration demonstrated potential application for the synthesis of chiral β-polychlorinated alkynes.

HPLC of Formula: 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Formula: C9H5N.

Uchikura, Tatsuhiro;Aruga, Kureha;Suzuki, Riku;Akiyama, Takahiko research published 《 Enantioselective Friedel-Crafts Alkylation Reaction of Pyrroles with N-Unprotected Alkynyl Trifluoromethyl Ketimines》, the research content is summarized as follows. Developed herein is an enantioselective Friedel-Crafts alkylation reaction of N-unprotected alkynyl trifluoromethyl ketimines with pyrroles catalyzed by chiral phosphoric acid to furnish chiral primary α-trifluoromethyl-α-(2-pyrrolyl)propargylamines with high enantioselectivity. Transformation of the alkynyl group of the adducts afforded optically active α-trifluoromethylated amines bearing various substituents such as alkyl, alkenyl, enyne, and triazole without loss of optical purity.

Formula: C9H5N, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts