Tag: M.W=100-150

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Name: 4-Ethynylbenzonitrile.

Kumar, Manoj;Verma, Shalini;Mishra, Vivek;Reiser, Oliver;Verma, Akhilesh K. research published 《 Visible-light-accelerated copper-catalyzed [3 + 2] cycloaddition of N-tosylcyclopropylamines with alkynes/alkenes》, the research content is summarized as follows. Copper-catalyzed [3 + 2] cycloadditions of N-tosylcyclopropylamine with alkynes and alkenes had been accomplished under visible light irradiation The developed approach was compatible with a range of functionalities and allows the synthesis of diversified aminated cyclopentene I [R = Ph, 4-MeOC₆H₄, 6-methoxy-2-naphthyl, etc.] and cyclopentane derivatives II [R¹ = Ph, 4-MeC₆H₄, Bz, etc.] being relevant for drug synthesis. The protocol was operationally simple and economically affordable as it does not require any ligand, base or additives. As the key step, the one-electron oxidation of the N-tosyl moiety by visible light-induced homolysis of a transient Cu(II)-tosylamide complex was proposed, providing a facile entry for N-centered radicals.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Name: 4-Ethynylbenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Related Products of 3032-92-6.

Lahtigui, Ouidad;Forster, Dan;Duchemin, Coralie;Cramer, Nicolai research published 《 Enantioselective Access to 3-Azabicyclo[3.1.0]hexanes by Cp^xRh^III Catalyzed C-H Activation and Cp*Ir^III Transfer Hydrogenation》, the research content is summarized as follows. A flexible two-step protocol for efficient and selective access such as 3-azabicyclo[3.1.0]hexanes I [R¹ = cyclopropyl, Ph, 3-thienyl, etc.; R² = Bn, PNB] was disclosed. A tailored Cp^xRhIII catalyst promoted alkenyl C-H functionalization of N-enoxysuccinimides engaging in rare cis-cyclopropanation of acrolein to access disubstituted cis-cyclopropanes in high enantio- and diastereoselectivity. Subsequently, in the presence of a broad range of primary amines, the dicarbonyl cis-cyclopropanes were efficiently and completely diastereoselectively cyclized by a Cp^*IrIII catalyst via an iterative aminative transfer hydrogen to an exquisite set of substituted 3-azabicyclo[3.1.0]hexanes.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Related Products of 3032-92-6

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Application In Synthesis of 3032-92-6.

Li, Huan;Wang, Fang;Zhu, Shengqing;Chu, Lingling research published 《 Selective Fluoromethyl Couplings of Alkynes via Nickel Catalysis》, the research content is summarized as follows. A Ni-catalyzed intermol. carbo-fluoromethylation of alkynes with aliphatic halides and fluoromethyl halides (BrCF₂H and ICH₂F) in the presence of zinc was described, enabling the facile and selective access to a diverse range of biol. valuable CF₂H/CH₂F-incorporated alkenes with excellent regio- and stereoselectivity. Notably, merging intramol. radical cyclization with fluoromethyl coupling enabled the expedient constructions of CF₂H/CH₂F-incorporated lactones and lactams with high efficiency and selectivity. Mechanistic studies disclosed that this catalytic protocol proceeded via a radical addition to an alkyne followed by selective coupling with the fluoromethyl unit.

Application In Synthesis of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Recommanded Product: 4-Ethynylbenzonitrile.

Li, Jiajie;Xu, Xin;Luo, Zhenli;Yao, Zhen;Yang, Ji;Zhang, Xin;Xu, Lijin;Wang, Peng;Shi, Qian research published 《 Rhodium(III)-Catalyzed Regioselective C-H Annulation and Alkenylation of 2-Pyridones with Terminal Alkynes》, the research content is summarized as follows. Cp*Rh(III)-catalyzed regioselective C-H annulation and alkenylation of 2-pyridones with terminal alkynes was developed. The cationic Cp*Rh(III) catalytic system containing FeCl₃ additive enables annulation of 1-(2-pyridyl)-2-pyridones with terminal alkynes, providing efficient access to 5,7-diarylated 2-quinolinones I [R = H, 4-Me, 3-Br, etc.; R¹ = H, 4-Me, 5-F, etc.; Ar = Ph, 2-MeC₆H₄, 2-naphthyl, etc.]. The reaction pathway could be switched to alkenylation with [Cp*RhCl₂]₂ as the catalyst, NaOAc as the additive and HOAc as the solvent, affording C6-alkenylated 1-(2-pyridyl)-2-pyridones II [R² = Ph, 3-MeC₆H₄, 2-naphthyl, etc.; R³ = H, 4-Me, 3-Br, etc.] in high yields. These protocols accommodated a wide range of substrates with good functional group compatibility.

Recommanded Product: 4-Ethynylbenzonitrile, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion. SDS of cas: 3032-92-6.

Li, Laiqiang;Hou, Zhong-Wei;Li, Pinhua;Wang, Lei research published 《 Electrochemical Dearomatizing Spirocyclization of Alkynes with Dimethyl 2-Benzylmalonates to Spiro[4.5]deca-trienones》, the research content is summarized as follows. An electrochem. dearomatizing spirocyclization of alkynes with di-Me 2-benzylmalonates for the preparation of spiro[4.5]deca-trienones had been developed. This approach adopted ferrocene (Cp₂Fe) as an electrocatalyst to produce carbon-centered radical intermediates from C-H-based malonates, which obviated the forthputting of noble-metal reagents, sacrificial chem. oxidants and 2-bromomalonates. A wide variety of spiro compounds were efficiently prepared with satisfactory results under mild conditions.

SDS of cas: 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. HPLC of Formula: 3032-92-6.

Kawamoto, Takuji;Kawabata, Takahiro;Noguchi, Kohki;Kamimura, Akio research published ã€?Vicinal Difunctionalization of Alkenes Using Vinyl Triflates Leading to γ-Trifluoromethylated Ketonesã€? the research content is summarized as follows. A new methodol. for the synthesis of γ-trifluoromethylated ketones from alkenes and vinyl triflate bifunctional reagents was reported. The reaction proceeded via the addition of a β-trifluoromethyl alkyl radical to a vinyl triflate, followed by β-cleavage. A one-pot version of the reaction for the vicinal functionalization of alkenes from alkynes was also demonstrated.

HPLC of Formula: 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Safety of 4-Ethynylbenzonitrile.

Kook, Ga Young;Kim, Daegeun;Chae, Min Ki;Ko, Haye Min research published ã€?Rhodium(II)-Catalyzed Highly Selective 1,3-Insertion Reactions Using N-Sulfonyl-1,2,3-Triazoles with Heteroaryl Ethers or Heteroaryl Alcoholsã€? the research content is summarized as follows. The transformation of N-sulfonyl-1,2,3-triazoles via insertion/rearrangement was achieved using 2-hydroxybenzimidazole or 2-alkoxybenzothiazole over 3 mol % Rh₂(Oct)₄ for the synthesis of α-((1H-benzo[d]imidazol-2-yl)amino) ketones I [R¹ = 3-chloropropyl, cyclohexen-1-yl, Ph, etc.; X = O, S, NH; R² = n-Bu, Ph, 4-MeC₆H₄, etc.] or (Z)-2-alkoxy-2-phenylethenamines II [R³ = Me, Ph, Bn, etc.; X = O, S; Y = S, O]. This regio- and stereoselective reaction proceeds under mild conditions, was tolerant of functional groups, and had a broad substrate scope. Notably, while the general rhodium-catalyzed reaction involved sigmatropic rearrangement from an allyl vinyl ether, the present synthetic methodol. prevents rearrangement owing to the benzimidazole group, allowed access to (Z)-olefins.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Safety of 4-Ethynylbenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Application In Synthesis of 3032-92-6.

Jaiswal, Kuldeep;Groutchik, Kristina;Bawari, Deependra;Dobrovetsky, Roman research published ã€?An “On-Demand”, Selective Dehydrogenative Borylation or Hydroboration of Terminal Alkynes Using Zn²⁺-based Catalystã€? the research content is summarized as follows. Cationic three-coordinate zinc tris(picolyl)phosphine complex catalyzes either dehydrogenative borylation of α-alkynes yielding alkynylboronates, or hydroboration affording vinylboronates, depending on catalyst load and reaction temperature An air-stable dicationic Zn²⁺ complex [Zn[P(CH₂py)₃]][B(C₆F₅)₃]₂ (1) in a tripod-type ligand with non-bound phosphorus base and three pyridinyl “arms” (TPPh) was synthesized. Remarkably, while 2 mol% of 1 at room temperature selectively catalyzed dehydrogenative borylation of terminal alkynes with HBPin, a lower loading of 1 (0.5 mol%) at 90° selectively promoted hydroboration reaction of the same alkynes skipping the dehydrogenative borylation step. The mode of action of 1 was proposed based on exptl. observations as well as the mechanism of dehydrogenative borylation was studied by DFT computations.

Application In Synthesis of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Electric Literature of 3032-92-6.

Jankovic, Dominik;Virant, Miha;Gazvoda, Martin research published ã€?Copper-Catalyzed Azide-Alkyne Cycloaddition of Hydrazoic Acid Formed In Situ from Sodium Azide Affords 4-Monosubstituted-1,2,3-Triazolesã€? the research content is summarized as follows. Authors report a copper-catalyzed cycloaddition of hydrogen azide (hydrazoic acid, HN₃) with terminal alkynes to form 4-substituted-1,2,3-triazoles in a sustainable manner. Hydrazoic acid was formed in situ from sodium azide under acidic conditions to react with terminal alkynes in a copper-catalyzed reaction. Using polydentate N-donor chelating ligands and mild organic acids, the reactions were realized to proceed at room temperature under aerobic conditions in a methanol-water mixture and with 5 mol % catalyst loadings to afford 4-substituted-1,2,3-triazoles in high yields. This method is amenable on a wide range of alkyne substrates, including unprotected peptides, showing diverse functional group tolerance. It is applicable for late-stage functionalization synthetic strategies, as demonstrated in the synthesis of the triazole analog of losartan. The preparation of orthogonally protected azahistidine from Fmoc-L-propargylglycine was realized on a gram scale. The hazardous nature of hydrazoic acid has been diminished as it forms in situ in <6% concentrations at which it is safe to handle. Reactions of distilled solutions of hydrazoic acid indicated its role as a reactive species in the copper-catalyzed reaction.

Electric Literature of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion. Related Products of 3032-92-6.

Ji, Xiaolei;Shen, Chaoren;Tian, Xinxin;Zhang, Hongru;Ren, Xinyi;Dong, Kaiwu research published �Asymmetric Double Hydroxycarbonylation of Alkynes to Chiral Succinic Acids Enabled by Palladium Relay Catalysis� the research content is summarized as follows. A Pd-catalyzed asym. double hydroxycarbonylation of terminal alkynes was developed by using relay catalysis, providing a highly efficient route to chiral succinic acids (41 examples, 76-94 %, 94-99 % ee). Key to success was the combinatorial use of a Pd precursor with two distinct phosphine ligands in one pot. The synthetic utilities of this protocol were showcased in the facile synthesis of key intermediates for chiral pharmaceuticals.

Related Products of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts