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Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 4897-25-0, is researched, Molecular C4H4ClN3O2, about Unit cell dimensions and space group of twinned crystals of 1-methyl-4-nitro-5-chloroimidazole, the main research direction is structure methylnitrochloroimidazole; imidazole methylnitrochloro structure; nitrochloromethylimidazole structure; chloronitromethylimidazole structure.Product Details of 4897-25-0.

The crystallog. parameters of the monoclinic title compound (I) (m.p. 147-8°) are a 3.826, b 14.369, c 11.569 Å, β 94.35.degree., d. (exptl.) = 1.682, Z = 4, d.(calculated) = 1.692, space group P21/c. Crystals of I were twinned.

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The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Pyridine-4-thiol(SMILESS: SC1=CC=NC=C1,cas:4556-23-4) is researched.Related Products of 178396-31-1. The article 《Hybrid octahedral Au nanocrystals and Ag nanohole arrays as substrates for highly sensitive and reproducible surface-enhanced Raman scattering》 in relation to this compound, is published in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices. Let’s take a look at the latest research on this compound (cas:4556-23-4).

Surface enhanced Raman scattering (SERS) substrates with excellent enhancement and reproducibility have seen continuous research in recent years. Herein, we report a high performance hybrid SERS substrate which is composed of octahedral Au nanocrystals (AuNCs) and Ag nanohole (AgNH) arrays to achieve both high enhancement and reproducibility. The octahedral AuNCs were prepared by controllable chem. synthesis and the AgNHs over 5 × 5 mm2 in area were fabricated by a surface plasmon lithog. (SPL) technique. The hybrid structure was prepared by self-assembly of the colloidal AuNCs onto the AgNHs. The SERS substrate shows an enhancement factor (EF) of 3.6 × 106, which is much higher than that of either the AuNCs or AgNHs. The high SERS enhancement is ascribed to the high-d. hotspots with a 3-dimensional (3D) distribution and the effect of plasmonic coupling from these hybrid structures. In addition, the substrate shows excellent reproducibility and stability. The relative standard deviation (RSD) is less than 7% and the SERS intensity only decreases by 32% after 100 days of exposure to air. It is expected that the designed hybrid structure of AuNCs and AgNHs with excellent SERS performance is a potential candidate for applications, such as in food safety, disease diagnosis, environmental monitoring and other practical trace detection.

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Computed Properties of C4H4ClN3O2. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 5-Chloro-1-methyl-4-nitroimidazole, is researched, Molecular C4H4ClN3O2, CAS is 4897-25-0, about The effect of electron-affinic radiosensitizers on ATP levels in V79 379A Chinese hamster cells. Author is Hodgkiss, R. J..

The ATP and nonprotein thiol content of Chinese hamster V79 379A cells were studied following treatment with electron-affinic radiosensitizers, i.e., misonidazole, Ro 05-9963, MOA-16, metronidazole, nitrofurentoin, CMNI, and 2,4-DNP. In cells in hypotonic medium, misonidazole, 2,4-DNP, and MOA-16 induced a concentration-dependent increase in cellular ATP after a 1-2-h lag paralleling the time courses of toxicity and nonprotein thiol depletion. Similar results were observed with nitrofurantoin, CMNI, and Ro 05-9963.

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So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Hamlyn, Richard J.; Jones, Richard H.; Ramsden, Christopher A. researched the compound: 5-Chloro-1-methyl-4-nitroimidazole( cas:4897-25-0 ).SDS of cas: 4897-25-0.They published the article 《Carbon-carbon bond formation via thermal intermolecular hydrogen atom transfer: two serendipitous heterocyclic examples》 about this compound( cas:4897-25-0 ) in Perkin 1. Keywords: chloro nitro thiophene reaction benzyl dihydro imidazole; imidazolyl thienyl methanol preparation crystal mol structure. We’ll tell you more about this compound (cas:4897-25-0).

Formation of an anomalous 3-nitrothiophene product, encountered during the preparation of potential bioreductive anti-cancer agents, is rationalized in terms of a hydrogen atom transfer mechanism which also accounts for the unexpected formation of previously described 5,5′-biimidazoles. Thus, reaction of 2-chloro-3-nitrothiophene with 2-benzyl-4,5-dihydro-1H-imidazole in propionitrile containing mol. sieves gave 62% imidazolylthienylmethanol I, which was x-ray crystallog. characterized.

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Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 4897-25-0, is researched, SMILESS is C1=NC(=C(Cl)[N]1C)[N+]([O-])=O, Molecular C4H4ClN3O2Journal, Fenxi Ceshi Xuebao called Determination of ten nitroimidazole residues in royal jelly by high performance liquid chromatography tandem mass spectrometry, Author is Xie, Wen; Chen, Xiaomei; Ding, Huiying; Hou, Jianbo; Xi, Junyang; Qian, Yan, the main research direction is royal jelly high performance liquid chromatog tandem mass spectrometry; nitroimidazole residue.Electric Literature of C4H4ClN3O2.

Nitroimidazoles and their hydroxy metabolites are banned substances with antibiotic and anticoccidial activity. They are suspected to be carcinogenic and mutagenic. In this paper, a rapid, sensitive and selective method for the determination of ten nitroimidazole residues, including dimetridazole(DMZ), 2-hydroxymethyl-1-methyl-5-nitroimidazole(HMMNI) or dimetridazole-OH(DMZOH), metronidazole(MNZ), metronidazole-OH(MNZOH), ronidazole(RNZ), 5-nitrobenzimidazole(NBI), ipronidazole(IPZ), ipronidazole-OH(IPZOH), 2-methyl-5-nitroimidazole(MNI) and 5-chloro-1-methyl-4-nitroimidazole(CMNI) in royal jelly was established by liquid chromatog.-tandem mass spectrometry (LC-ESI MS/MS). Methanol was used to precipitate protein, the supernatant solution was extracted with Et acetate under weak basic condition and cleaned up with Oasis(HLB) and C18 columns. The quant. detection was performed by LC-MS/MS on multiple reaction monitoring(MRM) mode under pos.-ion electrospray ionization. The isotope internal standards(D3-DMZOH, D3-DMZ, D3-RNZ, D3-IPZOH, D3-IPZ) were added into the sample solutions, and isotope dilution internal standard method or external standard method was used for quantitation anal. The results showed that the calibration curves of ten nitroimidazole residues were linear in the range of 5.0-60μg/kg with correlation coefficients more than 0.999. The recoveries of ten nitroimidazole residues at the spiked levels of 10, 20 and 50μg/kg were between 70% and 105% with RSDs less than 12.7%, and the quantitation limits were all 10μg/kg. The method was specific and accurate, and was suitable for the determination and confirmation of nitroimidazole residues in royal jelly samples.

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Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 4897-25-0, is researched, Molecular C4H4ClN3O2, about Electrochemical reduction of bifunctional organic compounds. XIII. N-methylnitroimidazole substitution in water-alcohol buffer media, the main research direction is polarog nitroimidazole pH cation effect; imidazole nitro polarog media effect.SDS of cas: 4897-25-0.

The polarog. reduction of I (R = H, Cl, Br, NO2; R1 = H, Br, NO2) was studied at pH 1.20-11.26 in the presence of different cations. Both the extent and mechanism of reduction depended on whether tetraalkylammonium or alkali metal cations were present.

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Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Nanomaterials called Charge-Transfer Process in Surface-Enhanced Raman Scattering Based on Energy Level Locations of Rare-Earth Nd3+-Doped TiO2 Nanoparticles, Author is Zhao, Zihao; Zhao, Xiang; Zhang, Mu; Sun, Xudong, which mentions a compound: 4556-23-4, SMILESS is SC1=CC=NC=C1, Molecular C5H5NS, Electric Literature of C5H5NS.

Surface-enhanced Raman scattering (SERS) for semiconductor nanomaterial systems is limited due to weak Raman signal intensity and unclear charge-transfer (CT) processes for chem. enhancement. Here, rare-earth element neodymium-doped titanium dioxide (Nd-TiO2) nanoparticles (NPs) were synthesized by the sol-gel method. The characterizations show that the doping of Nd ions causes TiO2 NPs to show an increase in the concentration of defects and change in the energy level structure. The CT process between Nd-TiO2 NPs substrate and probe mol. 4-Mercaptopyridine (4-Mpy) was innovatively analyzed using the relative energy level location relationship of the Dorenbos model. The SERS signal intensity exhibits an exponential enhancement with increasing Nd doping concentration and reaches its optimum at 2%, which is attributed to two factors: (1) The increase in the defect concentration is beneficial to the CT process between the TiO2 and the probe mol.; (2) the introduction of 4f electron orbital energy levels of rare-earth ions created unique CT process between Nd3+ and 4-Mpy. Moreover, the Nd-TiO2 NPs substrate shows excellent SERS performance in Raman signal reproducibility (RSD = 5.31%), the limit of detection (LOD = 10-6 M), and enhancement factor (EF = 3.79 x 104). Our work not only improves the SERS performance of semiconductor substrates but also provides a novel approach to the development of selective detection of probe mols.

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The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 5-Chloro-1-methyl-4-nitroimidazole(SMILESS: C1=NC(=C(Cl)[N]1C)[N+]([O-])=O,cas:4897-25-0) is researched.Category: chlorides-buliding-blocks. The article 《Determination of cysteine with 1-methyl-4-nitro-5-chloroimidazole》 in relation to this compound, is published in Chemia Analityczna (Warsaw, Poland). Let’s take a look at the latest research on this compound (cas:4897-25-0).

Cysteine was heated with 1-methyl-4-nitro-5-chloroimidazole in a pH 10 NH3 buffer for 1 h at 50° to form a 1:1 complex which had an absorption maximum at 410 nm. Beer’s law was obeyed for 10-5-10-3M cysteine.

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In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Immunosuppression by 9-alkyl-6-thiopurines, published in 1972, which mentions a compound: 4897-25-0, mainly applied to immunosuppression thiopurine derivative; antibody formation inhibition thiopurine, Recommanded Product: 4897-25-0.

6-Mercaptopurine [50-44-2], 9-butyl-6-mercaptopurine [6165-01-1], azathioprine [446-86-6], 9-butylazathioprine [20917-47-9], 6-methylthioinosine [342-69-8], chloroimidazole [4897-25-0], 6-thioguanine [154-42-7], 9-butyl-6-thioguanine [30546-08-8], guaneran [5581-52-2], 9-butylguaneran [36892-45-2], 6-thioguanosine [85-31-4], and 6-methylthioguanosine [34020-33-2] significantly suppressed the antibody response of mice to sheep red blood cells. Only 5-glutathionyl-1-methyl-4-nitroimidazole [36892-55-4] and 9-isobutylguaneran [36892-43-0] had no significant effect. Thus, 2 classes of 6-thiopurines have immunosuppressive activity: 9-unsubstituted derivatives which form nucleotide analogs inside cells and stable 9-alkyl derivatives which have a mechanism of action unrelated to nucleotide formation.

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Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 4556-23-4, is researched, Molecular C5H5NS, about Distinguishing Enantiomers by Tip-Enhanced Raman Scattering: Chemically Modified Silver Tip with an Asymmetric Atomic Arrangement, the main research direction is distinguishing enantiomer tip enhanced raman scattering modified silver tip; Raman spectroscopy; charge transfer; chirality; hydrogen bonding; silver.Product Details of 4556-23-4.

Discrimination between enantiomers is achieved by tip-enhanced Raman scattering (TERS) using a silver tip that is chem. modified by an achiral para-mercaptopyridine (pMPY) probe mol. Differences in the relative intensities of the pMPY spectra were monitored for three pairs of enantiomers containing hydroxy (-OH) and/or amino (-NH2) groups. The N: or N+-H functionality of the pMPY-modified tip participates in hydrogen-bond interactions with a particular mol. orientation of each chiral isomer. The asym. arrangement of silver atoms at the apex of the tip induces an asym. elec. field, which causes the tip to become a chiral center. Differences in the charge-transfer (CT) states of the metal-achiral probe system in conjunction with the asym. elec. field produce different enhancements in the Raman signals of the two enantiomers. The near-field effect of the asym. elec. field, which depends on the number of analyte functional groups capable of hydrogen-bond formation, improves the degree of discrimination.

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