Tag: M.W=100-200

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 22445-42-7, Name is 3,5-Dimethylbenzonitrile, molecular formula is C9H9N. In an article, author is Darge, Abenazer W.,once mentioned of 22445-42-7, Computed Properties of C9H9N.

Uranium concentration using reactive polymer thin films for spectroscopic analyses

This contribution describes the development of reactive polymer films for the concentration of uranium from circumneutral pH solutions for spectroscopic analyses. These films were prepared by grafting uranium-selective polymers from polyethersulfone (PES) films via UV-initiated polymerization, and by introducing uranium-selective functional groups to polyacrylonitrile (PAN) films by chemical reaction. Ellipsometry was used to study poly(phosphoric acid 2-hydroxyethyl methacrylate ester) film growth kinetics on PES films. X-ray photoelectron spectroscopy of modified PAN films revealed conversion of nitrile groups to amidoxime groups to be as high as 40% and showed that the extent and depth of reaction could be varied precisely. Static uptake experiments with solutions of depleted uranium spiked with U-233 were conducted to determine uranium binding capacities and kinetics of the modified polymer films at different pH values from 4 to 8. Sorption isotherm data were fitted to the Langmuir model, and the highest sorption capacities of 1.09 x 10(-2) +/- 1.03 x 10(-3) mmol m(-2) and 1.02 x 10(-2) +/- 3.00 x 10(-3) mmol m(-2) were obtained at pH 6 for modified PAN (M-PAN) and PES (M-PES) films. Capacities at pH 4 and 8 were lower and could be explained by differences in sorption mechanisms. Uranium batch uptake kinetics followed a pseudo-second order rate model. Equilibrium uptake was attained within 3 h for M-PAN film and 1 h for M-PES film. Alpha spectroscopy pulse height spectra were analyzed to study the role of selective layer film thickness on peak energy resolution. Full width at half maximum values from 29 to 41 keV were recorded for M-PAN film and from 26 to 45 keV for M-PES film. Whereas uranium uptake increased with selective layer film thickness and varied with polymer chemistry/extent of modification, the peak energy resolution was independent of layer thickness and polymer chemistry within the experimental measurement uncertainties. Results from this work are being used to guide the development of thin-film composite membrane-based detection methods for the rapid, fieldable analysis of radionuclides in water for nuclear forensics investigations and environmental studies.

Interested yet? Keep reading other articles of 22445-42-7, you can contact me at any time and look forward to more communication. Computed Properties of C9H9N.

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 2920-38-9, Name is [1,1′-Biphenyl]-4-carbonitrile, molecular formula is C13H9N, belongs to nitriles-buliding-blocks compound. In a document, author is Arslan, Cagrialp, introduce the new discover, Category: nitriles-buliding-blocks.

The effects of fiber silane modification on the mechanical performance of chopped basalt fiber/ABS composites

The purpose of this study was to examine the effects of silane coupling agent modifications on the mechanical performance of the basalt fiber (BF)-reinforced acrylonitrile-butadiene-styrene (ABS) composites. Three different silane coupling agents were used. The mechanical properties of the composites were determined by the tensile, flexural, impact tests, and dynamic mechanical analysis (DMA). According to the test results, the tensile strength increased with the use of (3-aminopropyl) triethoxysilane (AP) and 3-(trimethoxysilyl) propylmethacrylate (MA), while the use of (3-glycidyloxypropyl) trimethoxysilane (GP) reduced the tensile strength. All the silane modifications improved the flexural strength and modulus and the highest improvement was achieved with the use of AP. No remarkable difference was observed in impact properties with the use of silane coupling agents. The addition of BF significantly improved the elastic modulus of the ABS regardless of the modification type, while the further improvements were achieved through the use of AP and MA. In brief, AP showed the highest performance among the studied silane coupling agents due to the covalent bond formation between the amino group of AP and the nitrile group of styrene-acrylonitrile (SAN) matrix.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 2920-38-9. Category: nitriles-buliding-blocks.

Electric Literature of 3288-99-1, The chemical industry reduces the impact on the environment during synthesis 3288-99-1, name is 2-(4-(tert-Butyl)phenyl)acetonitrile, I believe this compound will play a more active role in future production and life.

In a 300 mL-reaction flask equipped with a rectification column and a separating tank, 11.3 g (65.2 mmol) of 4-tert-butylphenylacetonitrile, 10.8 g (59.5 mmol) of 1,3,4-trimethylpyrazol-5-carboxylic acid ethyl ester, 100 g of heptane, 10.0 g of 5-ethyl-2-picoline, and 3.0 g of diethylene glycol monoethyl ether were added, the atmosphere was substituted with nitrogen, then azeotropic dehydration was carried out by heating at 90 to 95 C. for 1 hour. The temperature was maintained, 13.8 g (71.5 mmol) of 28% sodium methoxide methanol solution was added dropwise over 5 hours, and the resulting mixture was further reacted for 5 hours. After cooling to 30 C. or less, 108 g of water was added to separate out heptane phase and obtain an aqueous phase. A quantitative analysis of the obtained aqueous phase with liquid chromatography showed that the aqueous phase contained 17.0 g (yield 92.1%) of 3-oxo-2-(4-tert-butylphenyl)-3-(1,3,4-trimethylpyrazol-5-yl)propionitrile.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-(4-(tert-Butyl)phenyl)acetonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Fukuda, Kenzo; Kondo, Yasuo; Tanaka, Norio; Suzuki, Hideaki; Ohnari, Masatoshi; Nishio, Koichi; US2006/178523; (2006); A1;,
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Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 2338-75-2, name is 4-(Trifluoromethyl)phenylacetonitrile, A new synthetic method of this compound is introduced below., Formula: C9H6F3N

To a solution of 4- trifluoromethyl phenylacetonitrile (40 g, 215 mmol) in 2N NH3/MeOH (400 mL) was added Raney Ni ((at)4.0 g). The reaction mixture was placed in a par-shaker and shook under 50 Lb pressure overnight. The solution was filtered through celite and concentrated in vacuo to yield the desired amine (38 g, 95%). ESI-MS calc. For C9H10F3N: 189; Found: 190 (M+H).

The synthetic route of 2338-75-2 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; MERCK & CO., INC.; WO2005/110409; (2005); A2;,
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Related Products of 21524-39-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 21524-39-0, name is 2,3-Difluorobenzonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

Step A: 3-Fluoro-2-(2H-1 ,2,3-triazol-2-yl)benzonitrile and 3-fluoro-2-(1 H-1 ,2,3-triazol-1 -yl)benzonitrile. A mixture of 2,3-difluorobenzonitrile (4.0 g, 28.8 mmol), 2H-1 ,2,3-triazole (1 .9 g, 28.8 mmol) in DMF (85.0 mL) and K2CO3 (7.9 g, 57.5 mmol) were heated to 125 C for 1 .5 h. After cooling to rt, water was added and the mixture extracted with EtOAc (2 X). The combined organics were washed with brine and dried (Na2SO ). Purification via FCC (10-100% EtOAc in hexanes) gave two products. 3-Fluoro-2-(2H-1 ,2,3-triazol-2- yl)benzonitrile (1 .6 g, 29%), 1H NMR (CDCI3): 7.99 (s, J = 6.6 Hz, 2H), 7.67 – 7.63 (m, 1 H), 7.61 – 7.53 (m, 2H), 7.26 (s, 6 H) and 3-fluoro-2-(1 H-1 ,2,3-triazol- 1 -yl)benzonitrile (2.0 g, 38%) 1H NMR (CDCI3): 7.97 (dd, J = 4.4, 2.8 Hz, 1 H), 7.95 (d, J = 1 .2 Hz, 1 H), 7.70 (tt, J = 5.7, 2.8 Hz, 1 H), 7.65 (td, J = 8.1 , 4.9 Hz, 1 H), 7.62 – 7.57 (m, 1 H).

The synthetic route of 2,3-Difluorobenzonitrile has been constantly updated, and we look forward to future research findings.

Reference:
Patent; JANSSEN PHARMACEUTICA NV; BRANSTETTER, Bryan, James; LETAVIC, Michael, A.; LY, Kiev, S.; RUDOLPH, Dale, A.; SAVALL, Brad, M.; SHAH, Chandravadan, R.; SHIREMAN, Brock, T.; WO2011/50202; (2011); A1;,
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Synthetic Route of 1194-02-1, The chemical industry reduces the impact on the environment during synthesis 1194-02-1, name is 4-Fluorobenzonitrile, I believe this compound will play a more active role in future production and life.

Preparation of BB8: 4-Fluoro-N-hydroxy-benzamidine; To a solution of the 4-fluoro-benzonitrile (10.0 g, 52.9 mmol) in ethanol (200 mL), the solution of NH2OH-HCl (4.0 g, 58.2 mmmol) in H20 (4 mL) was added dropwise. The mixture was stirred vigorously at about 65 C and stood overnight. The analysis by TLC indicated the complete consumption of starting material. The solution was concentrated to remove the solvent. The residue was dissolved in DCM and washed with water, brine, dried over Na2S04 and concentrated in vacuum to afford 4-Fluoro-N-hydroxy-benzamidine as pale- yellow solid (BB8).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Fluorobenzonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; ABBOTT LABORATORIES; CUSACK, Kevin, P.; BREINLINGER, Eric, C.; FIX-STENZEL, Shannon, R.; STOFFEL, Robert, H.; WOLLER, Kevin, R.; WO2011/71570; (2011); A1;,
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Electric Literature of 53312-79-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 53312-79-1, name is 3-Amino-4-chlorobenzonitrile, This compound has unique chemical properties. The synthetic route is as follows.

Under nitrogen protection, a water separator was installed in a 2L four-necked flask, and 152.6 g of 2-chloro-5-cyanoaniline, 130 g of benzaldehyde, 12 g of p-toluenesulfonic acid and 1.2 L of xylene were added, and the mixture was refluxed for 6 hours.The reaction can be stopped without significant water droplets in the water separator.After cooling to room temperature, it was washed with 100 mL of 10% aqueous sodium hydroxide solution, and the organic phase was decomposed under reduced pressure.The obtained residue was distilled under reduced pressure to give 215 g of the desired product N-benzylidene-2-chloro-5-cyanoaniline. The gas chromatographic content was 98.4%, and the yield was 89.3%.

The chemical industry reduces the impact on the environment during synthesis 3-Amino-4-chlorobenzonitrile. I believe this compound will play a more active role in future production and life.

Reference:
Patent; Shanghai Kangpeng Technology Co., Ltd.; Zeng Yuan; Zhou Yan; Li Bolan; Chen Xiaobin; Wang Daoxiang; Yang Jianhua; (19 pag.)CN108276294; (2018); A;,
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Synthetic Route of 623-00-7,Some common heterocyclic compound, 623-00-7, name is 4-Bromobenzonitrile, molecular formula is C7H4BrN, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: Preparation of biphenyl-4-carbonitrile (38): Pd(OAc)2 (2.3 mg, 1 mmol %), 4-bromo-benzonitrile (37) (182 mg, 1.0 mmol), 4,4,6-trimethyl-2-phenyl-[1,3,2] dioxaborinane (26) (224.4 mg, 1.1 mmol), Cs2CO3 (650 mg, 2 mmol), toluene (4 mL)-methanol (1 mL) were mixed together in a small reaction tube and the mixture was heated at 60 C. The reaction progress was followed by TLC (15% ethyl acetate:hexanes). After the starting materials were consumed the mixture was cooled and filtered through celite followed by washing with toluene. The solvent was evaporated under reduced pressure and the residue was purified by flash chromatography on silica gel (15% ethyl acetate:hexanes) to obtain the title compound in 95% yield. 1H NMR (400 MHz, CDCl3): delta 7.74-7.67 (m, 4H), 7.62-7.58 (m, 2H), 7.53-7.41 (m, 3H). 13C NMR (100.6 MHz, CDCl3): delta 145.9, 139.4, 133.7, 132.9, 132.8, 129.4, 128.9, 128.0, 127.5, 119.2, 111.1

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 4-Bromobenzonitrile, its application will become more common.

Reference:
Article; Myslinska, Malgorzata; Heise, Glenn L.; Walsh, Dana J.; Tetrahedron Letters; vol. 53; 24; (2012); p. 2937 – 2941;,
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Application of 939-79-7, These common heterocyclic compound, 939-79-7, name is 4-Methyl-3-nitrobenzonitrile, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

A mixture of 4-methyl-3-nitrobenzontitrile (2.4Ig), 10% Pd on C ( ~lg) and ethanol was stirred under hydrogen. After 24 hours the reaction mixture was filtered through Celite, and the solvent reduced in vacuo and purified using flash chromatography to yield 3-amino-4-methyl-benzonitrile (1.2Ig).

Statistics shows that 4-Methyl-3-nitrobenzonitrile is playing an increasingly important role. we look forward to future research findings about 939-79-7.

Reference:
Patent; F. HOFFMANN-LA ROCHE AG; WO2009/93049; (2009); A1;,
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Reference of 15996-76-6, A common heterocyclic compound, 15996-76-6, name is 4-(Aminomethyl)benzonitrile hydrochloride, molecular formula is C8H9ClN2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

100 g (0.593 mol) of 4-cyanobenzylamine¡ÁHCl were dissolved in 1.2 l of dioxane and 600 ml of 2 N NaOH. 142.3 g (0.652 mol) of di(tert-butyl)pyrocarbonates were added in two portions over 10 min at 0 C. The pH was adjusted to 9-10 by adding 2 N NaOH, and the mixture was stirred for a further 4 h. The solvent was removed in vacuo, and the residue was taken up with ethyl acetate, washed 3¡Á each with 5% KHSO4 and NaCl-saturated water and then dried over Na2SO4. The solvent was removed in vacuo (white solid). Yield: 132.6 g (0.57 mol) of white solid, HPLC: 51.6% B

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; Stuerzebecher, Joerg; Steinmetzer, Torsten; Schweinitz, Andrea; Sturzebecher, Anne; Donnecke, Daniel; US2007/66539; (2007); A1;,
Nitrile – Wikipedia,
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