Tag: M.W=150-200

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Related Products of 31643-49-9.

Malyasova, A. S.;Kostrova, E. A.;Abramov, I. G.;Maizlish, V. E.;Koifman, O. I. research published 《 Synthesis, acid-base interactions, and photostability of copper(II) tetrakis(3,5-di-tert-butylbenzoyloxy)phthalocyanine》, the research content is summarized as follows. 3,4-Dicyanophenyl 3,5-di-tert-butylbenzoate was synthesized for the 1st time. Copper tetrakis(3,5-di-tert-butylbenzoyloxy)phthalocyaninate was also obtained for the 1st time using template cyclotetramerization. Compounds were identified by UV-visible, IR, ¹H and ¹³C NMR spectroscopies. The features of the acid-base interaction and the acidity constants of the copper tetrakis(3,5-di-tert-butylbenzoyloxy)phthalocyaninate protonated forms, as well as Cu tetra(4-tert-butyl)phthalocyaninate and its ligand in the system CH₂Cl₂-100% HO₂CCF₃ were studied. The macrocycle’s protonation includes two reversible stepwise reactions, namely, mono- and diprotonation at the meso N atoms. The acidity constants dependence on the chem. structure of mols. was revealed. The phthalocyanines photocatalytic stability in benzene was also studied. An increase in the electron-donating properties of the macrocycle decreases the complex stability, and vise versa, a decrease of the electron d. in the macrocycle increases the photostability.

Related Products of 31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Recommanded Product: 4-Nitrophthalonitrile.

Mantareva, Vanya;Kussovski, Vesselin;Orozova, Petya;Angelov, Ivan;Durmus, Mahmut;Najdenski, Hristo research published 《 Palladium Phthalocyanines Varying in Substituents Position for Photodynamic Inactivation of Flavobacterium hydatis as Sensitive and Resistant Species》, the research content is summarized as follows. Antimicrobial photodynamic therapy (aPDT) has been considered as a promising methodol. to fight the multidrug resistance of pathogenic bacteria. The procedure involves a photoactive compound (photosensitizer), the red or near IR spectrum for its activation, and an oxygen environment. In general, reactive oxygen species are toxic to biomols. which feature a mechanism of photodynamic action. The present study evaluates two clin. isolates of Gram-neg. Flavobacteriumhydatis (F. hydatis): a multidrug resistant (R) and a sensitive (S) strain. Both occur in farmed fish, leading to the big production losses because of the inefficacy of antibiotics. Palladium phthalocyanines (PdPcs) with methylpyridiloxy groups linked peripherally (pPdPc) or non-peripherally (nPdPc) were studied with full photodynamic inactivation for 5.0 μM nPdPc toward both F. hydatis, R and S strains (6 log), but with a half of this value (3 log) for 5.0 μM pPdPc and only for F. hydatis, S. In addition to the newly synthesized PdPcs as a “pos. control” was applied a well-known highly effective zinc phthalocyanine (ZnPcMe). ZnPcMe showed optimal photocytotoxicity for inactivation of both F. hydatis R and S. The present study is encouraging for a further development of aPDT with phthalocyanines as an alternative method to antibiotic medication to keep under control the harmful pathogens in aquacultures′ farms.

31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., Recommanded Product: 4-Nitrophthalonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Reference of 31643-49-9.

Mei, Lan;Cui, Xu;Wei, Juncheng;Duan, Qian;Li, Yanhui research published 《 Metal phthalocyanine-based conjugated microporous polymer/carbon nanotube composites as flexible electrodes for supercapacitors》, the research content is summarized as follows. Conjugated microporous polymers with active functional groups have attracted more and more attentions in energy conversion systems. However, their low elec. conductivity results in low capacitance, thus limiting their practical application. Herein, conjugated microporous polymer with triphenylamine aldehyde linked to metal phthalocyanines (MNC) is synthesized and then compounded with high-conductivity carbon nanotubes (CNTs) (denoted as CoNCCs) by vacuum filtration. Moreover, CoNCCs exhibit flexibility, which could be served as a self-standing and binder-free flexible electrode of supercapacitors. As a result, the optimized CoNCCs as the flexible electrode show high specific capacitance of 213.4 F g^-1 at 0.5 A g^-1. In addition, the higher capacity retention rate 85.3% can be retained after 1750 cycles at 20 A g^-1. The good electrochem. properties can be attributed to the synergistic effect and strong dual-phase interaction between MNC and CNTs. This work opens the way to develop high-performance and low environmental footprint organic electrode materials for SCs.

Reference of 31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Reference of 31643-49-9.

Li, Shuangshuang;Tang, Xinwei;Zhang, Yawei;Lan, Qianqian;Hu, Zhiwei;Li, Le;Zhang, Nan;Ma, Piming;Dong, Weifu;Tjiu, Wengweei;Wang, Zicheng;Liu, Tianxi research published 《 Corrosion-Resistant Graphene-Based Magnetic Composite Foams for Efficient Electromagnetic Absorption》, the research content is summarized as follows. Designing and fabricating high-performance microwave absorption materials with efficient electromagnetic absorption and corrosion resistance becomes a serious and urgent concern. Herein, novel corrosion-resistant graphene-based carbon-coated iron (Fe@C) magnetic composite foam is fabricated via self-assembly of iron phthalocyanine/Fe₃O₄ (FePc hybrid) on the graphene skeletons under solvothermal conditions and then annealing at high temperature As a result, the rational construction of a hierarchical impedance gradient between graphene skeletons and Fe@C particles can facilitate the optimization in impedance matching and attenuation characteristic of the foam, realizing the efficient dissipation for incident electromagnetic waves. Addnl., the performance of electromagnetic absorption can be controllably regulated by optimizing annealing temperature and/or time. More importantly, the formation of a carbon-coated iron structure substantially improves the corrosion resistance of magnetic particles, endowing the composite foam with excellent stability and durability in microwave absorption performance.

31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., Reference of 31643-49-9

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Name: 4-Nitrophthalonitrile.

Li, Siqi;Huang, Zhipeng;Liu, Huifang;Liu, Meijiang;Zhang, Chaofeng;Wang, Feng research published 《 Polar hydrogen species mediated nitroarenes selective reduction to anilines over an [FeMo]S_x catalyst》, the research content is summarized as follows. An efficient approach for the chemoselective synthesis of arylamines RNH₂ (R = 2-fluorophenyl, 2-acetyl-4,5-dimethoxyphenyl, 2-pyridyl, etc.) from nitroarenes RNO₂ and hydrazine over an iron-molybdenum sulfide catalyst ([FeMo]S_x) is presented. The heterogeneous hydrogen transfer reduction can be efficiently carried out at 30°C and provides anilines with 95-99% selectivities. The in situ gas product anal. demonstrates that [FeMo]Sx can catalyze the decomposition of N₂H₄ to H* species, not H₂. Combining with the kinetic anal. of the aniline generation rates from nitrobenzene and intermediates, the nitro group reduction to the nitroso group is confirmed to be the rate-determining step. The pos. slope of Hammett’s equation suggests that the critical intermediate in the rate-determining step is in the neg. state, which suggests that the active H* should be in polar states (H^δ- and H^δ+). These findings will provide a novel route for the synthesis of substituted anilines and broaden the application of MoS_x catalysts under mild conditions.

Name: 4-Nitrophthalonitrile, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Computed Properties of 31643-49-9.

Li, Jian;Wu, Minjie;Rong, Jianxin;Zhang, Qian;Yu, Xiaoyan;Zhang, Qingxin research published 《 Synthesis and Properties of Phthalonitrile Polymer with a Novel Piperazine Structural Curing Agent》, the research content is summarized as follows. A novel autocatalytic phthalonitrile (PN) monomer containing piperazine structure, namely 4-[1-(4-aminophenyl)-4-(4-phenyl)piperazine-oxy]phthalonitrile (APPN), is synthesized from the nucleophilic substitution reaction of 1-(4-aminophenyl)-4-(4-hydroxyphenyl)piperazine and 4-nitrophthalonitrile. The structure of the APPN monomer is characterized by NMR (NMR) spectroscopy and Fourier Transform IR (FTIR) spectroscopy. The novel 4-nitrophthalonitrile end-capped compound APPN is firstly used to promote the curing reaction of PN monomer 1,3-bis(3,4-dicyanophenoxy)benzene (m-BDB). Thermogravimetric Anal. (TGA) and Dynamic Mech. Anal. (DMA) showed that the PN resin in the presence of 10% of APPN possessed outstanding thermal and thermo-oxidative stabilities as well as good mech. properties, better than the properties of those with 20% of APPN and 10% of APPH. Its glass transition temperature (T_g) is higher than 400°, and the polymer loses 5% of its weight (T_5%) at 524° and shows a storage modulus of 1373 MPa at 400°.

31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., Computed Properties of 31643-49-9

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Quality Control of 31643-49-9.

Kantekin, Halit;Yalazan, Halise;Barut, Burak;Gungor, Omer;Unluer, Dilek;Demirbas, Umit;Ozel, Arzu;Durmus, Mahmut research published ã€?Dual-purpose both peripheral and non-peripheral triazole substituted Zn^II, Mg^II and Pb^II phthalocyanines: Synthesis, characterization, photophysicochemical and acetylcholinesterase inhibitory propertiesã€? the research content is summarized as follows. Both peripheral and non-peripheral 4-(3,4-dimethoxyphenethyl)-5-ethyl-2H-1,2,4-triazol-3(4H)-one substituted zinc(II), magnesium(II) and lead(II) phthalocyanines were synthesized in this paper. Techniques used to illuminate the structure of these phthalocyanines included FT-IR, MALDI TOF, UV-Vis, NMR spectroscopy. The Zn^IIPcs (p/np–ZnPcs), Mg^IIPcs (p/np–MgPcs) and Pb^IIPcs (p/np–PbPcs) exhibited outstanding solubility in common organic solvents such as 1,4-Dioxane, acetonitrile, chloroform, dichloromethane, DMF, dimethylsulfoxide, Et acetate and THF. The photophysicochem. properties of Zn^IIPcs, Mg^IIPcs and Pb^IIPcs were researched in DMSO. The positions of the substituents (peripheral or non-peripheral) and the effects of the central metal ions (Zn²⁺, Mg²⁺, Pb²⁺) on the photophysicochem. properties were reported by comparison. The singlet oxygen quantum yield values of Zn^IIPcs, Mg^IIPcs and Pb^IIPcs ranged from 0.11 to 0.78 in DMSO. The newly synthesized peripherally tetra substituted zinc(II) phthalocyanine (p–ZnPc) exhibited high singlet oxygen generation in DMSO compared to unsubstituted zinc(II) phthalocyanine used as standard These results indicate that the (p–ZnPc) can be a candidate as photosensitizer for PDT. Besides, the inhibitory properties of the compounds were determined using the spectrophotometric method on AChE and α-glucosidase. IC₅₀ values showed that np-MgPc has highest inhibitory actions among the tested compounds on AChE and α-glucosidase.

Quality Control of 31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. SDS of cas: 31643-49-9.

Karaca, Huseyin;Delibas, Nagihan Caylak;Saglam, Serap;Piskin, Hasan;Sezer, Serdar;Hokelek, Tuncer;Teker, Murat research published ã€?Metallophthalocyanines derived with phenyl sulfide by bridging triazole using click chemistry: Synthesis, Computational Study, Redox Chemistry and Catalytic Activityã€? the research content is summarized as follows. Synthesis and characterization of new metallophthalocyanines (M = Zn, Co(II) and Ni(II)) carrying four new triazole units in peripheral positions was presented. First, 4-(prop-2-yn-1-yloxy)phthalonitrile, l3, was synthesized. Second, azidomethyl Ph sulfide, 4, was added to this structure to obtain a triazole unit catalyzed by sodium ascorbate and CuSO₄.5H₂O in DMSO. Common spectroscopic methods such as FTIR, ¹H-NMR, ¹³C-NMR, HRMS and UV-visible spectroscopy techniques was used for characterization of synthesized structures. The mol. structure of the phthalonitrile compound 5 was confirmed by single-crystal x-ray diffraction experiment Morover, by using HF and B3LYP method and 6-31++g(d,p) basis set, ¹H and ¹³C NMR chem. shifts, IR and UV-visible spectra were theor. calculated in gas phase for the optimized structure of 5. The obtained FTIR spectra and NMR spectra showed that the desired mols. were synthesized, and mass spectra confirmed these mols. Electronic absorption spectra showed that phthalocyanines are non-aggregable mols. The cyclic voltammetry data of the phthalocyanines showed that the Pc-6 has two reduction reactions and two oxidation reactions while the Pc-7 and Pc-8 have one reduction reaction and one oxidation reaction. Furthermore, the cobalt(II)phthalocyanine, Pc-7, was studied as oxidation catalyst for the catalytic oxidation of 2-mercaptoethanol. Turnover number, initial reaction rate and the oxygen consumption values were found in the catalytic oxidation of 2-mercaptoethanol as 18.09, 0.12μmol.s^-1 and 6.88μmol.min^-1, resp.

31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., SDS of cas: 31643-49-9

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Category: nitriles-buliding-blocks.

Karakilic, Emel;Alim, Zuhal;Emirik, Mustafa;Baran, Arif research published ã€?Some characteristics of new and innovative COX inhibitor derivatives: Potent hCA-I and hCA-II inhibitors supported by molecular docking studiesã€? the research content is summarized as follows. In this study, two novel metallophthalocyanines (ZnPc and CoPc) were synthesized using the corresponding metal salts 4-(4-(4-[4-chlorophenyl]-5-methylisoxazol-3-yl)phenoxy)-phthalonitrile (11), prepared from the reaction of 4-nitrophthalonitrile and 4-(4-[4-chlorophenyl]-5-methylisoxazol-3-yl)phenol (9). These metallophthalocyanines (MPcs) showed quite solubility in organic solvents such as dichloromethane (DCM), THF (THF), DMF (DMF), and dimethylsulfoxide (DMSO). The novel compounds 11a and 11b have been characterized using their UV-Vis, FT-IR, ¹H NMR, ¹³C NMR, X-Ray, and MALDI-TOF mass spectra. Supporting information concerning with the study has been supplied. Photochem., photophys., and cyclic voltammetry properties of these novel 4-(4-[4-chlorophenyl]-5-methylisoxazol-3-yl)phenoxy substituted metallophthalocyanines (11a and 11b) were determined in DMF. DNA binding, metal chelating effect assay, and DPPH [2,2-diphenyl-1-picrylhydrazyl hydrate] radical scavenging assay and electrochem. studies of MPcs were investigated. Further, the inhibitory effects of the COX-inhibitor based novel metallophthalocyanines (11a and 11b) and their ligands (10 and 11) were examined on human erythrocyte carbonic anhydrase I (hCA-I) and II (hCA-II) isoenzymes, and the synthesized mols. exhibited very strong inhibitory effects on both isoforms. In addition, the hCA-I and hCA-II inhibition potential of Zn (II) and Co (II) Phthalocyanine complexes was supported by mol. docking studies. The binding interaction of metallophthalocyanines complexes 11a, 11b enzymes were analyzed in detail.

Category: nitriles-buliding-blocks, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Electric Literature of 31643-49-9.

Karakilic, Emel;Alim, Zuhal;Gunel, Aslihan;Baran, Arif research published ã€?A versatile study of novel A₃B-type unsymmetric zinc(II) phthalocyanines containing thiazolidin-4-one: Their, carbonic anhydrase I, II isoenzymes, and xanthine oxidase inhibitors evaluationã€? the research content is summarized as follows. In this study, four novel phthalocyanine complexes containing zinc metal were synthesized. After preparing the starting compounds 2-(4-hydroxyphenyl)-3-phenylthiazolidin-4-one 1 and 2-(4-(2-hydroxyethoxy)phenyl)-3-phenylthiazolidin-4-one 3 by the conventional method, they were reacted with 4-nitrophthalonitrile sep. using K₂CO₃ in DMF. Compounds 2 and 4, are well-documented compounds for obtaining phthalocyanines. Subsequently, synthesized phthalonitrile compounds 2 and 4 were reacted with Zn(II) salt at high temperature in the presence of DBU to convert them into targeted sym. (2a, 4a) and unsym. (2b, 4b) phthalocyanines under suitable conditions. Their photochem., photophys., and electrochem. features were then examined These metallophthalocyanines indicated good solubility in some organic solvents, such as DMSO, DMF, THF, DCM, and CHCl₃. Furthermore, the structures of ligands (1, 2, 3, 4) were determined by ¹H NMR, ¹³C NMR, and FT-IR spectrometry, while complexes (2a, 2b, 4a, 4b) were determined by FT-IR, UV-Vis, fluorescence, and MALDI-TOF spectrometry. Inhibitory effects of ligand and phthalocyanine compounds (1, 2, 3, 4, 2a, 2b, 4a, 4b) against human erythrocyte carbonic anhydrase I (hCA I) and II (hCA II) isoenzymes, as well as cow’s milk xanthine oxidase (XO), were examined It was found that 2a, 2b, 4a, and 4b had strong inhibition effects at micromolar levels against all three. The compounds 2b and 4b showed stronger inhibition effects for hCA I and II than 2a and 4a. In the case of XO, although the inhibition effects of these mols. (2b, 4a, 4b) were similar, 2a had the strongest inhibition effect. Since CA and XO inhibitors are the target mols. of drug development studies to be used in the treatment of many diseases, the results of this study will aid drug design studies in the development of new XO and CA inhibitors.

Electric Literature of 31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts