Tag: M.W=200-250

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Product Details of C9H6BrNO.

Fang, Xuerong;Li, Jinsi;Zhong, Qianqian;Ming, Xin research published 《 Synthesis and cytostatic activity of emissive 7-thiazolyl-7-deazapurine nucleosides》, the research content is summarized as follows. 7-Functionalized 7-deazapurine fluorescent nucleosides are highly important for biotechnol. applications. Here, 7-substituted 7-deaza-2′-deoxyguanosines, e.g. I, comprising a 4H-cyclopenta[d]thiazole ring are obtained by Hantzsch synthesis reaction of 7-thioamide-7-deaza-2′-deoxyguanosine with aromatic α-bromocarbonyl compounds (61-85%). Their photophys. properties are determined by UV and fluorescence spectroscopy, and the cytostatic activities are evaluated by MTT assay. All compounds exhibit strong solvatochromicity and pH-dependent fluorescence in aqueous solutions, indicating their promising ability to be fluorescent probes. The 7-substituted 7-deaza-2′-deoxyguanosines, e.g. I, exert cytostatic activities, which means they have the potential to be candidate for theranostics.

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., Product Details of C9H6BrNO

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Formula: C8F4N2.

Feng, Xiaoquan;Peng, Donglai;Shan, Meixia;Niu, Xinpu;Zhang, Yatao research published 《 Facilitated propylene transport in mixed matrix membranes containing ZIF -8@Agmim core-shell hybrid material》, the research content is summarized as follows. The ZIF-8@Agmim core-shell hybrid material was synthesized via a favorable post-modification method of ion exchange (PMIE). This infrequent ZIF-8@Agmim core-shell structure maintains a well-integrated pore size that is almost the same as ZIF-8. The similar equilibrium isotherms with ZIF-8 and better kinetic separation toward propylene/propane than ZIF-8 render ZIF-8@Agmim to be an interesting candidate for propylene/propane separation The core-shell hybrid nanomaterial was further used as nanofillers in the polymer of intrinsic microporosity matrix (PIM-1) for propylene/propane separation The resultant mixed-matrix membranes (MMMs) exhibited a simultaneous increase in C₃H₆ permeability and C₃H₆/C₃H₈ ideal selectivity compared to pure polymer membrane owing to a synergistic effect of mol. sieving from ZIF-8 and π-complexation of Ag⁺ with propylene. The separation performance of the prepared MMM surpasses the upper bound line of polymer membranes. Furthermore, the hybrid materials possess superb photochem. stability and the corresponding MMMs exhibit excellent anti-aging property and long-term stability.

Formula: C8F4N2, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , 1835-49-0.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Reference of 1835-49-0.

Corrado, Tanner J.;Huang, Zihan;Huang, Dezhao;Wamble, Noah;Luo, Tengfei;Guo, Ruilan research published 《 Pentiptycene-based ladder polymers with configurational free volume for enhanced gas separation performance and physical aging resistance》, the research content is summarized as follows. Polymers of intrinsic microporosity (PIMs) have shown promise in pushing the limits of gas separation membranes, recently redefining upper bounds for a variety of gas pair separations However, many of these membranes still suffer from reductions in permeability over time, removing the primary advantage of this class of polymer. In this work, a series of pentiptycene-based PIMs incorporated into copolymers with PIM-1 are examined to identify fundamental structure-property relationships between the configuration of the pentiptycene backbone and its accompanying linear or branched substituent group. The incorporation of pentiptycene provides a route to instill a more permanent, configuration-based free volume, resistant to phys. aging via traditional collapse of conformation-based free volume PPIM-i.p.-C and PPIM-np-S, copolymers with C- and S-shape backbones and branched isopropoxy and linear n-propoxy substituent groups, resp., each exhibited initial separation performance enhancements relative to PIM-1. Addnl., aging-enhanced gas permeabilities were observed, a stark departure from the typical permeability losses pure PIM-1 experiences with aging. Mixed-gas separation data showed enhanced CO2/CH4 selectivity relative to the pure-gas permeation results, with only ∼20% decreases in selectivity when moving from a CO2 partial pressure of ∼2.4 to ∼7.1 atm (atm. pressure) when utilizing a mixed-gas CO2/CH4 feed stream. These results highlight the potential of pentiptycene’s intrinsic, configurational free volume for simultaneously delivering size-sieving above the 2008 upper bound, along with exceptional resistance to phys. aging that often plagues high free volume PIMs.

1835-49-0, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , Reference of 1835-49-0

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. SDS of cas: 1835-49-0.

Cosey, Whitney K.;Balkus, Kenneth J. Jr.;Ferraris, John P.;Musselman, Inga H. research published 《 Reduced Aging in Carbon Molecular Sieve Membranes Derived from PIM-1 and MOP-18》, the research content is summarized as follows. Carbon mol. sieve membranes (CMSMs) commonly lose permeability over time due to the collapse of micropores. This decline in permeability, due to the densification of the membrane, is known as phys. aging. CMSMs derived from polymers of intrinsic microporosity (PIM-1) are highly affected by phys. aging, with declines in permeability greater than 60% over time. The densification of CMSMs derived from this high-free-volume polymer precursor is thermodynamically driven by the collapse of large unconnected graphene domains to reach a more stable conformation (i.e., graphite). This study describes a novel strategy to mitigate phys. aging by pillaring the CMSM using copper nanoparticles. Highly soluble metal-organic polyhedra-18 (MOP-18) was introduced into PIM-1 with loadings up to 40 wt/wt to form a mixed-matrix membrane (MMM). Pyrolysis of the MMM at 550°C resulted in the in situ formation of copper metal nanoparticles that acted as pillars for the graphene sheets within the CMSM, preventing the collapse of the micropores, thus minimizing the aging of the CMSM. Single gas permeation measurements of CO₂ and CH₄ were made on the pristine polymer-derived CMSM and the copper-pillared CMSM at 35°C and 2 bar to confirm the membranes’ resistance to phys. aging. The CH₄ permeability for the PIM-1 CMSM decreased by ∼60%, from 64 to 27 Barrers, over a period of 7 days, while the copper-pillared PIM-1 CMSM remarkably showed essentially no decline in CH₄ permeability. This research demonstrates a general approach to reducing phys. aging in CMSMs.

1835-49-0, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , SDS of cas: 1835-49-0

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion. Product Details of C9H6BrNO.

Das, Sumit;Singh, Bhagat;Fadikar, Pulak;Barman, Piyali Deb;Paira, Rupankar research published 《 Application of recyclable base-washed graphene oxide for one-pot conversion of 2-aminopyridines into 3-iodo-imidazo[1,2-a]pyridines at room temperature in water》, the research content is summarized as follows. A green synthetic protocol for cyclization of 2-aminopyridines I (R = H, 3-Me, 4-Me, 4-Cl, 4-Br, 5-Cl) with 2-bromoacetophenones R¹C(O)CH₂Br (R¹ = 4-bromophenyl, 3-tert-butylphenyl, naphthalen-2-yl, etc.) to prepare imidazo[1,2-a]pyridines, followed by their successive iodination in one-pot manner to give II (R² = H, 7-Me, 8-Me, 6-Cl, 7-Cl, 7-Br), employing base-washed graphene oxide as the catalyst, in water has been described. The current approach has offered to carry out the reaction in water medium at room temperature and the base-washed graphene oxide catalyst has provided excellent product yield (upto 81%) and can also be recycled effortlessly upto 5 catalytic cycles, through a simple base-wash protocol. The catalyst is an inexpensive, environmentally benign, green, and heterogeneous platform and has been characterized by IR, Raman, SEM and TEM studies.

Product Details of C9H6BrNO, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Category: nitriles-buliding-blocks.

Demirtas, Ilknur;Ertas, Erdal;Topal, Sebahat;Ozturk, Turan research published 《 Electropolymers of 4-(thieno[3,2-b]thiophen-3-yl)benzonitrile extended with thiophene, 3-hexylthiophene and EDOT moieties; their electrochromic applications》, the research content is summarized as follows. Three new π-conjugated 4-(thieno[3,2-b]thiophen-3-yl)benzonitrile based monomers having thiophene, 3-hexylthiophene and EDOT at the peripherals were synthesized. Their electropolymerization produced the corresponding electroactive polymers, P1, P2, and P3, which exhibited electrochromic properties with color developments from red to blue, orange-yellow to pale-blue, and purple to pale-gray, resp. Functional design of the monomers with electron deficient benzonitrile at β-position of thieno[3,2-b]thiophene (TT) and electron-rich thienyl groups at the peripherals influenced the HOMO and LUMO levels and, thereby, reduced the band gap of the conjugated polymers. Considering the band gaps of electropolymerized TT based polymers in the literature, the polymer P3, obtained through electropolymerization, had a comparable band gap of 1.73 eV. Electrochromic devices (ECD) of the new polymers displayed different optical contrasts (ΔT%) of 20% at 507 nm, 25% at 443 nm, and 34% at 579 nm for P1/PProDOP, P2/PProDOP, and P3/PProDOP, resp. Furthermore, they had modest switch times of 1.2-1.7 s for bleaching and 0.9-1.7 s for coloring. The polymers, P3/PProDOP, bearing EDOT moieties, had a reasonable coloration efficiency (CE) of 240 cm²/C at 579 nm, excellent permanent memory effect, and high stability of color switch, retaining 88% of its electroactivity after 500 cycles, switching at the applied voltages of -0.2 and + 1.1 V.

Category: nitriles-buliding-blocks, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Product Details of C9H6BrNO.

Deshpande, Anant;Dhawale, Shashikant;Bari, Sanjaykumar;Bonde, Chandrakant research published 《 Design, synthesis and biological investigation of some novel quinazolin-4(3H)-one tethered 1,3,4-thiadiazole-thiol motifs as direct enoyl acyl carrier protein reductase inhibitors》, the research content is summarized as follows. In this study two noteworthy pharmacophores quinazolin-4(3H)-one and 1,3,4-thiadiazole through methylene bridge were utilized to design, synthesize and characterize some novel 2-Me quinazolin-4(3H)-one and 6-chloro-2-Me quinazolin-4(3H)-one tethered S-substituted-1,3,4-thiadiazole-thiol structural analogs resp. as direct Mycobacterium Tuberculosis (MTB) enoyl acyl carrier protein reductase (InhA) inhibitors. Structural analogs of quinazolin-4(3H)-one tethered 1,3,4-thiadiazole-thiol I [R = H, Cl; R¹ = 4-Me, 4-F, 3-NO₂, etc.] through methylene bridge by functional group modifications in core scaffold followed by computational studies to select promising compds was designed. The mol. docking of designed compunds was carried out using schrodinger Glide XP into the active site of MTB InhA with protein data bank code (PDB ID: 2H7M). The interactions were evaluated based on the glide G score compared with reference standard isoniazid. Ten new compounds I were synthesized, characterized and screened for their in-vitro antitubercular activity by Microplate Almar Blue Assay (MABA) method followed by cytotoxicity evaluation of compounds I [R = H ; R¹ = 4-F, 4-OMe] using Vero cell line. All the designed compounds of series I had drug-like characteristics and were non-toxic to normal cells. In the mol. docking studies, compounds I [R = H, Cl; R¹ = 4-F, 4-OMe] demonstrated strong binding affinity in the active region of MTB InhA protein and retained necessary amino acid interaction, similar to co-crystal 2H7M. Synthesized compounds I were found to have good antitubercular activity. Out of the series the compounds I [R = H ; R¹ = 4-F, 4-OMe] were found to possess excellent antitubercular activity equipotent to reference standard streptomycin with min. inhibitory concentration (MIC) value of 6.25μg/mL. The cytotoxic potential of compounds I [R = H ; R¹ = 4-F, 4-OMe] showed remarkable selectivity index against Vero cell line. The findings of this study highlighted the importance of tethering two pharmacophoric motifs in one compound to develop novel antitubercular agents that can be exploited as promising leads as direct InhA inhibitors.

Product Details of C9H6BrNO, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Recommanded Product: Tetrafluoroterephthalonitrile.

Devarajan, Anirudh;Asuquo, Edidiong D.;Ahmad, Mohd Zamidi;Foster, Andrew B.;Budd, Peter M. research published 《 Influence of Polymer Topology on Gas Separation Membrane Performance of the Polymer of Intrinsic Microporosity PIM-Py》, the research content is summarized as follows. The polymer synthesis of 2,3,5,6-tetrafluoro-4-pyridinecarbonitrile-3,3,3′,3′-tetramethyl-1,1′-spirobisindane-5,5′,6,6′-tetrol copolymer, termed PIM-Py, was investigated under different solvent (DMF and dimethylacetamide/dichlorobenzene) and temperature (65-160°C) conditions to produce a range of topol. different polymer samples. Characterization of the polymers, particularly with proton NMR spectroscopy and multiple detector SEC anal., indicated that, like PIM-1, the polymerizations proceeded with a degree of polymer chain branching. This is attributed to the occurrence of monosubstitution reactions, instead of disubstitution, which eventually leads to a significant proportion of colloidal network formation. However, all polymer samples remained soluble/dispersible in chloroform at the concentration required to cast self-standing films. This work reports the first examination of PIM-Py as a membrane for gas separation applications. The most structurally diverse PIM-Py samples produced films that exhibited selectivity/permeability balances in single gas permeation studies above the 2008 Robeson upper bound for the CO₂/N₂ gas pair. Indeed, a film cast from the highest colloidal network content sample surpassed the recently introduced 2019 CO₂/N₂ upper bound. After 143 days of aging, a 40μm self-standing membrane still exhibited a single gas CO₂ permeability of 4480 barrer and an ideal CO₂/N₂ selectivity of 45. The polymers produced in lower temperature reactions in DMF exhibited gas separation performances very similar to a structurally regular “normal” PIM-1 polymer, sitting on or around the 2008 Robeson upper bound line. Single gas permeation measurements to determine CO₂/CH₄ selectivity showed similar trends across the range of polymer samples, without generally reaching high selectivities as for the CO₂/N₂ pair. Mixed gas CO₂/CH₄ permeation measurements with aging were also completed for PIM-Py membranes, which indicated similar gas separation performance to a structurally regular PIM-1 polymer. This study would suggest that, like PIM-1, gas separation performance of PIM-Py is greatly influenced by the topol. balance toward branched and network material within the polymer sample.

Recommanded Product: Tetrafluoroterephthalonitrile, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , 1835-49-0.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Quality Control of 20099-89-2.

De-Zordo Banliat, Arnaud;Grollier, Kevin;Damond, Aurelie;Billard, Thierry;Dagousset, Guillaume;Magnier, Emmanuel;Pegot, Bruce research published 《 Solvent-free nucleophilic selenocyanation with [bmim][SeCN]. Direct access to perfluoroalkylselenide compounds》, the research content is summarized as follows. Available online-1-n-butyl-3-methylimidazolium selenocyanate ([bmim][SeCN]) proved to be a very efficient reagent for selenocyanation of alkyl halides RBr [R = n-decyl, 6-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)hexyl, 9H-fluoren-9-yl, etc.]. As part of an eco-friendly process, no organic solvents were used during the transformation and reaction times were reduced by using microwave as a heating source. The ionic liquid was carefully recycled in two different ways. Selenocyanate compounds RSeCN were successfully transformed into (trifluoromethyl or polyfluoro)selenides RSeR¹ (R¹ = CF₃, CF₂Br, C₂F₅) in a one-pot two step procedure.

Quality Control of 20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. COA of Formula: C9H6BrNO.

Dhanavath, Ramulu;Dharavath, Ravinder;Kothula, Devender;Bitla, Sampath;Yaku, Gugulothu;Birdaraju, Saritha;Puchakayala, Muralidhar Reddy;Atcha, Krishnam Raju research published 《 Synthesis and biological evaluation of novel 2-arylquinoline-3-fused thiazolo [2,3-c]1,2, 4-triazole heterocycles as potential antiproliferative and antimicrobial agents》, the research content is summarized as follows. A series of novel 2-arylquinoline-3-fused thiazolo[2,3-c]1,2,4-triazole heterocycles I [R = H, Me; R¹ = H, Cl, OMe; R² = H, Me; R³ = H, OMe; R⁴ = H, Cl, OMe, CN] were efficiently synthesized using simple conventional methods in good yields. The structure of newly synthesized mols. was characterized on the basis of their IR, ¹H NMR, ¹³C NMR and mass spectral data. Among compounds I, compounds I [R = R² = R³ = H ; R¹ = R⁴ = Cl], I [R = R² = R³ = H, Me; R¹ = R⁴ = OMe], I [R = R¹ = R² = R³ = H; R⁴ = Cl], I [R = R¹ = R² = R³ = H; R⁴ = OMe] exhibited highly significant antiproliferative activity against two cancer cell lines C6 (nerve cells) and MCF-7 (human breast adenocarcinoma cells) when compared with standard reference Doxorubicin. In vitro antimicrobial activities of target compounds compounds I [R = R² = R³ = H ; R¹ = R⁴ = Cl], I [R = R² = R³ = H, Me; R¹ = R⁴ = OMe], I [R = R¹ = R² = R³ = H; R⁴ = Cl], I [R = R¹ = R² = R³ = H; R⁴ = OMe], I [R = R² = R³ = H ; R¹ = OMe, R⁴ = Cl] were effectuated on Gram-pos. Staphylococcus aurus (ATCC 25923), Bacillus subtilis (ATCC 6633) and Gram-neg. strains Klebsiella Pneumonia (ATCC 31488) and Escherichia coli (ATCC 25966) strains and found to exhibit promising activity against standard Ciprofloxacin drug. Further, when in vitro antifungal activity was conducted on Aspergillus flavus and Aspergillus niger strains compounds I [R = R² = R³ = H ; R¹ = R⁴ = Cl], I [R = R² = R³ = H, Me; R¹ = R⁴ = OMe], I [R = R¹ = R² = R³ = H; R⁴ = Cl], I [R = R¹ = R² = R³ = H; R⁴ = OMe] were exhibited potent activity when compared with standard Fluconazole drug moiety.

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., COA of Formula: C9H6BrNO

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts