Reference of 26830-96-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 26830-96-6, name is 2-Amino-4-methylbenzonitrile, This compound has unique chemical properties. The synthetic route is as follows.
EXAMPLE 120 4-(2-Cyano-5-methylanilino)-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine The title compound was prepared from a mixture of 4-chloro-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.193 mmol) and 2-cyano-5-methylaniline (38 mg, 0.290 mmol) similar to Example 117 and isolated as a yellow solid (8 mg, 12%). 1H NMR (CDCl3): 9.62-9.61 (m, 1H), 8.75-8.69 (m, 2H), 8.08 (s, 1H), 7.62 (s, 1H), 7.60 (d, J=8.1 Hz, 1H), 7.46-7.41 (m, 1H), 7.12 (dd, J=0.9, 8.1 Hz, 1H), 7.00 (s, 1H), 2.52 (s, 3H).
The chemical industry reduces the impact on the environment during synthesis 2-Amino-4-methylbenzonitrile. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Cytovia, Inc.; US2003/69239; (2003); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts