Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 19924-43-7, name is 2-(3-Methoxyphenyl)acetonitrile, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C9H9NO
In a 10 mL single-neck round bottom flask under argon protection,A suspension of sodium dispersion in toluene (28.7% by weight, 5.00 mmol) was added followed by anhydrous tetrahydrofuran (1.0 mL),Dibenzo-18-crown-6 (5.00 mmol) was added at 0 C and stirred vigorously for 5 min. A solution of 1e (73.6 mg, 0.5 mmol) in anhydrous tetrahydrofuran (2.0 mL) was added, and the mixture was stirred vigorously at 0 C for 20 minutes. Then n-PrOH (5.00 mmol) was added. The reaction mixture was stirred vigorously at 0 C for 1 hour, and the reaction was quenched with a saturated aqueous sodium bicarbonate solution (2.0 mL). Anhydrous ether was added and the mixture was extracted with saturated sodium chloride solution. The organic phase was dried, concentrated, and separated by column chromatography to obtain 47.7 mg of the target compound 2e in a yield of 78%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 19924-43-7.
Reference:
Patent; China Agricultural University; An Jie; Luo Shihui; Ding Yuxuan; (13 pag.)CN110734414; (2020); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts