In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 29509-06-6, name is 4-Methyl-3-oxopentanenitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: 4-Methyl-3-oxopentanenitrile
Under nitrogen atmosphere, the compound of Example 2A (8.03g, 72mmol) was dissolved in alcohol (50 mL). Methylhydrazine (3.32g, 72mmol) was added. The resultant mixture was slowly warmed and refluxed with stirring. The reaction was kept for 3 hr. The reaction was stopped and cooled to room temperature. Alcohol was rotary-evaporated to obtain a crude product as oil. The crude product was purified with column chromatography (eluant: petroleum ether/ethyl acetate = 1: 1) to give 5.2 g of the title compound. MS (ESI): m/z 140 (M+H)+
The synthetic route of 29509-06-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Hande Starlake Bioscience Co., Ltd.; Hande Pharma Limited; LI, Chenxi; SHEN, Weisheng; FANG, Yang; LE, Xiaoyong; EP2578587; (2013); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts