Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 95-11-4, name is 5-Norbornene-2-carbonitrile, A new synthetic method of this compound is introduced below., name: 5-Norbornene-2-carbonitrile
Hydrogenation of nonborn-5-ene-2-carbonitrile 1d was performed similarly, using sodium borohydride (0.3 g, 0.008 mol), 15 mL of isopropanol, anhydrous nickel(II) chloride (0.5 g, 0.004 mol), and nitrile 1d (12 g, 0.1 mol). The reaction duration was 12 h, the temperature was 70C. 2-Aminomethylnorbornane 2d, content 5.5 wt %. Mass spectrum, m/e (Irel, %): 125 (27) [M], 108 (16), 95 (21), 79 (38), 66 (100), 56 (18). Bis(2-norbornylmethyl)amine 3d, content 89 wt %. Mass spectrum, m/e (Irel, %): 235 (13) [M+2], 234 (81) [M+1], 138 (100) [C7H11CH2NH=CH2]+, 109 (19), 67 (35), 44 (42). Tris(2-norbornylmethyl)amine 4d, content 2 wt %. Mass spectrum, m/e (Irel, %): 340 (1) [M-1], 246 (100) [M – C7H11], 152 (14), 109 (4), 79 (3), 67 (17).
The synthetic route of 95-11-4 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Mokhov; Popov; Shcherbakova; Russian Journal of General Chemistry; vol. 86; 2; (2016); p. 273 – 280; Zh. Obshch. Khim.; vol. 86; 2; (2016); p. 245 – 252,8;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts