Sun, Kai published the artcileRadical annulation of a designed diene system: access to nitro-benzo[b]azepines, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks), the main research area is nitromethyl benzazepine preparation; allyl arylvinyl aniline chemoselective regioselective radical annulation.
Herein, a novel O2N·-triggered ordered addition/7-endo cyclization reaction of N-allylic o-(arylvinyl)anilines I (R1 = H, F, Cl, Br, Me, MeO, R2 = H; R1 = H, R2 = Cl, Me; R3 = Ts, PhCO, Cbz; R4 = H, Me; Ar = Ph, 2-ClC6H4, 4-MeC6H4, etc.) with excellent chemo- and regioselectivity is described. With such a strategy, 28 structurally diverse (nitromethyl)benzo[b]azepines II were prepared Large-scale operation and handy N-Ts and N-Cbz deprotection revealed the promising utility of this methodol. Mechanistic studies suggested that the reaction proceeds through a radical pathway.
Chemical Communications (Cambridge, United Kingdom) published new progress about Benzazepines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks).
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts